guanidine has been researched along with Neuromuscular Diseases in 2 studies
Guanidine: A strong organic base existing primarily as guanidium ions at physiological pH. It is found in the urine as a normal product of protein metabolism. It is also used in laboratory research as a protein denaturant. (From Martindale, the Extra Pharmacopoeia, 30th ed and Merck Index, 12th ed) It is also used in the treatment of myasthenia and as a fluorescent probe in HPLC.
guanidine : An aminocarboxamidine, the parent compound of the guanidines.
Neuromuscular Diseases: A general term encompassing lower MOTOR NEURON DISEASE; PERIPHERAL NERVOUS SYSTEM DISEASES; and certain MUSCULAR DISEASES. Manifestations include MUSCLE WEAKNESS; FASCICULATION; muscle ATROPHY; SPASM; MYOKYMIA; MUSCLE HYPERTONIA, myalgias, and MUSCLE HYPOTONIA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Treatment with guanidine hydrochloride resulted in clinical improvement of the neuromuscular disease, but the patient died of refractory leukemia." | 2.37 | Eaton-Lambert syndrome in a patient with acute T cell lymphocytic leukemia. ( Clinton, ME; Manian, FA; Morrow, JD; Stein, RS, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Trojaborg, W | 1 |
| Flagstad, A | 1 |
| Morrow, JD | 1 |
| Manian, FA | 1 |
| Clinton, ME | 1 |
| Stein, RS | 1 |
1 review available for guanidine and Neuromuscular Diseases
| Article | Year |
|---|---|
Eaton-Lambert syndrome in a patient with acute T cell lymphocytic leukemia.
Topics: Aged; Electromyography; Female; Guanidine; Guanidines; Humans; Leukemia-Lymphoma, Adult T-Cell; Medi | 1988 |
1 other study available for guanidine and Neuromuscular Diseases
| Article | Year |
|---|---|
A hereditary neuromuscular disorder in dogs.
Topics: Animals; Dog Diseases; Dogs; Edrophonium; Electrophysiology; Evoked Potentials; Female; Guanidine; G | 1982 |