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guanidine and Muscular Dystrophy, Duchenne

guanidine has been researched along with Muscular Dystrophy, Duchenne in 2 studies

Guanidine: A strong organic base existing primarily as guanidium ions at physiological pH. It is found in the urine as a normal product of protein metabolism. It is also used in laboratory research as a protein denaturant. (From Martindale, the Extra Pharmacopoeia, 30th ed and Merck Index, 12th ed) It is also used in the treatment of myasthenia and as a fluorescent probe in HPLC.
guanidine : An aminocarboxamidine, the parent compound of the guanidines.

Muscular Dystrophy, Duchenne: An X-linked recessive muscle disease caused by an inability to synthesize DYSTROPHIN, which is involved with maintaining the integrity of the sarcolemma. Muscle fibers undergo a process that features degeneration and regeneration. Clinical manifestations include proximal weakness in the first few years of life, pseudohypertrophy, cardiomyopathy (see MYOCARDIAL DISEASES), and an increased incidence of impaired mentation. Becker muscular dystrophy is a closely related condition featuring a later onset of disease (usually adolescence) and a slowly progressive course. (Adams et al., Principles of Neurology, 6th ed, p1415)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Morcos, PA1
Li, Y1
Jiang, S1
Kang, JK1
Malerba, A1
Popplewell, L1
Foster, K1
Dickson, G1

Other Studies

2 other studies available for guanidine and Muscular Dystrophy, Duchenne

ArticleYear
Vivo-Morpholinos: a non-peptide transporter delivers Morpholinos into a wide array of mouse tissues.
    BioTechniques, 2008, Volume: 45, Issue:6

    Topics: Animals; Cells, Cultured; Disease Models, Animal; Drug Delivery Systems; Dystrophin; Fluorescent Ant

2008
Antisense-induced myostatin exon skipping leads to muscle hypertrophy in mice following octa-guanidine morpholino oligomer treatment.
    Molecular therapy : the journal of the American Society of Gene Therapy, 2011, Volume: 19, Issue:1

    Topics: Animals; Cell Proliferation; Cells, Cultured; Exons; Genetic Therapy; Guanidine; Hypertrophy; Mice;

2011