guanidine has been researched along with Malaria in 8 studies
Guanidine: A strong organic base existing primarily as guanidium ions at physiological pH. It is found in the urine as a normal product of protein metabolism. It is also used in laboratory research as a protein denaturant. (From Martindale, the Extra Pharmacopoeia, 30th ed and Merck Index, 12th ed) It is also used in the treatment of myasthenia and as a fluorescent probe in HPLC.
guanidine : An aminocarboxamidine, the parent compound of the guanidines.
Malaria: A protozoan disease caused in humans by four species of the PLASMODIUM genus: PLASMODIUM FALCIPARUM; PLASMODIUM VIVAX; PLASMODIUM OVALE; and PLASMODIUM MALARIAE; and transmitted by the bite of an infected female mosquito of the genus ANOPHELES. Malaria is endemic in parts of Asia, Africa, Central and South America, Oceania, and certain Caribbean islands. It is characterized by extreme exhaustion associated with paroxysms of high FEVER; SWEATING; shaking CHILLS; and ANEMIA. Malaria in ANIMALS is caused by other species of plasmodia.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Structural features associated with the antimalarial activity of the marine natural product crambescidin 800 were studied using synthetic analogues of the related compound ptilomycalin A." | 7.73 | Antimalarial activity of crambescidin 800 and synthetic analogues against liver and blood stage of Plasmodium sp. ( Black, GP; Concepcion, GP; Diquet, B; Howard-Jones, AG; Ibana, JA; Ireland, CM; Lazaro, JE; Mahmoudi, N; Mangalindan, GC; Mazier, D; Moore, CG; Murphy, PJ; Nitcheu, J; Thomas, DA, 2006) |
| "Structural features associated with the antimalarial activity of the marine natural product crambescidin 800 were studied using synthetic analogues of the related compound ptilomycalin A." | 3.73 | Antimalarial activity of crambescidin 800 and synthetic analogues against liver and blood stage of Plasmodium sp. ( Black, GP; Concepcion, GP; Diquet, B; Howard-Jones, AG; Ibana, JA; Ireland, CM; Lazaro, JE; Mahmoudi, N; Mangalindan, GC; Mazier, D; Moore, CG; Murphy, PJ; Nitcheu, J; Thomas, DA, 2006) |
| "Guanidine hydrochloride was found to selectively lyse trophozoite- and schizont-infected red blood cells, yielding highly synchronous and viable rings." | 1.51 | Efficient synchronization of Plasmodium knowlesi in vitro cultures using guanidine hydrochloride. ( Chim-Ong, A; Cui, L; Ngernna, S; Nguitragool, W; Roobsoong, W; Sattabongkot, J, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (62.50) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 2 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ngernna, S | 1 |
| Chim-Ong, A | 1 |
| Roobsoong, W | 1 |
| Sattabongkot, J | 1 |
| Cui, L | 1 |
| Nguitragool, W | 1 |
| Degardin, M | 1 |
| Wein, S | 1 |
| Duckert, JF | 1 |
| Maynadier, M | 1 |
| Guy, A | 1 |
| Durand, T | 1 |
| Escale, R | 1 |
| Vial, H | 1 |
| Vo-Hoang, Y | 1 |
| GUPTA, PR | 1 |
| GUGA, PC | 1 |
| MAY, EL | 1 |
| KING, H | 1 |
| TONKIN, IM | 1 |
| CURD, FH | 1 |
| DAVEY, DG | 1 |
| ROSE, FL | 1 |
| HUVE, P | 1 |
| Lazaro, JE | 1 |
| Nitcheu, J | 1 |
| Mahmoudi, N | 1 |
| Ibana, JA | 1 |
| Mangalindan, GC | 1 |
| Black, GP | 1 |
| Howard-Jones, AG | 1 |
| Moore, CG | 1 |
| Thomas, DA | 1 |
| Mazier, D | 1 |
| Ireland, CM | 1 |
| Concepcion, GP | 1 |
| Murphy, PJ | 1 |
| Diquet, B | 1 |
8 other studies available for guanidine and Malaria
| Article | Year |
|---|---|
Efficient synchronization of Plasmodium knowlesi in vitro cultures using guanidine hydrochloride.
Topics: Erythrocytes; Guanidine; Humans; Malaria; Parasitology; Plasmodium knowlesi; Schizonts; Sorbitol | 2019 |
Development of the first oral bioprecursors of bis-alkylguanidine antimalarial drugs.
Topics: Administration, Oral; Animals; Antimalarials; Female; Guanidine; Malaria; Mice; Plasmodium; Plasmodi | 2014 |
Studies in antimalarials; some R- and R'-disubstituted guanidines.
Topics: Antimalarials; Guanidine; Guanidines; Malaria | 1948 |
Attempts to find new antimalarials; guanidine and biguanide derivatives of phenanthrene.
Topics: Antimalarials; Biguanides; Guanidine; Guanidines; Malaria; Phenanthrenes | 1947 |
Antiplasmodial action and chemical constitution; guanidines and diguanides.
Topics: Antimalarials; Guanidine; Guanidines; Malaria | 1946 |
Studies on synthetic antimalarial drugs; some biguanide derivatives as new types of antimalarial substances with both therapeutic and causal prophylactic activity.
Topics: Antimalarials; Biguanides; Guanidine; Guanidines; Humans; Malaria | 1945 |
[Malaria and diguanyl].
Topics: Guanidine; Guanidines; Humans; Malaria | 1950 |
Antimalarial activity of crambescidin 800 and synthetic analogues against liver and blood stage of Plasmodium sp.
Topics: Animals; Antimalarials; Cells, Cultured; Disease Models, Animal; Erythrocytes; Guanidine; Hepatocyte | 2006 |