guanidine has been researched along with Liver Steatosis in 3 studies
Guanidine: A strong organic base existing primarily as guanidium ions at physiological pH. It is found in the urine as a normal product of protein metabolism. It is also used in laboratory research as a protein denaturant. (From Martindale, the Extra Pharmacopoeia, 30th ed and Merck Index, 12th ed) It is also used in the treatment of myasthenia and as a fluorescent probe in HPLC.
guanidine : An aminocarboxamidine, the parent compound of the guanidines.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Leptin, the product of the obese gene, is an adipocyte-secreted protein hormone playing a key role in the progression of obesity and hepatic steatosis." | 7.80 | Synthesis and biological evaluation of novel urea- and guanidine-based derivatives for the treatment of obesity-related hepatic steatosis. ( Chen, J; Chen, L; Liang, X; Ma, L; Pei, H; Ran, Y; Wang, G, 2014) |
| " The methylation of phosphatidylethanolamine to form choline has been extensively studied in the context of fatty liver disease." | 3.96 | Disruption of hepatic one-carbon metabolism impairs mitochondrial function and enhances macrophage activity in methionine-choline-deficient mice. ( da Silva, RP; Eudy, BJ; Fernandez, G; Lai, J; Mathews, CE; McDermott, CE, 2020) |
| "Leptin, the product of the obese gene, is an adipocyte-secreted protein hormone playing a key role in the progression of obesity and hepatic steatosis." | 3.80 | Synthesis and biological evaluation of novel urea- and guanidine-based derivatives for the treatment of obesity-related hepatic steatosis. ( Chen, J; Chen, L; Liang, X; Ma, L; Pei, H; Ran, Y; Wang, G, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Eudy, BJ | 1 |
| McDermott, CE | 1 |
| Fernandez, G | 1 |
| Mathews, CE | 1 |
| Lai, J | 1 |
| da Silva, RP | 1 |
| Liang, X | 1 |
| Pei, H | 1 |
| Ma, L | 1 |
| Ran, Y | 1 |
| Chen, J | 1 |
| Wang, G | 1 |
| Chen, L | 1 |
| MOHNIKE, G | 1 |
3 other studies available for guanidine and Liver Steatosis
| Article | Year |
|---|---|
Disruption of hepatic one-carbon metabolism impairs mitochondrial function and enhances macrophage activity in methionine-choline-deficient mice.
Topics: Adenosine; Animals; Carbon; Choline; Choline Deficiency; Diet; Disease Models, Animal; Fatty Liver; | 2020 |
Synthesis and biological evaluation of novel urea- and guanidine-based derivatives for the treatment of obesity-related hepatic steatosis.
Topics: 3T3-L1 Cells; Animals; Diet, High-Fat; Fatty Liver; Gene Expression Regulation; Guanidine; Humans; L | 2014 |
[STUDY OF THE MECHANISM OF ACTION OF GUANIDINE DERIVATIVES].
Topics: Animals; Antihypertensive Agents; Blood Glucose; Diabetes Mellitus; Dogs; Fatty Acids; Fatty Liver; | 1963 |