guanidine has been researched along with Leukemia in 4 studies
Guanidine: A strong organic base existing primarily as guanidium ions at physiological pH. It is found in the urine as a normal product of protein metabolism. It is also used in laboratory research as a protein denaturant. (From Martindale, the Extra Pharmacopoeia, 30th ed and Merck Index, 12th ed) It is also used in the treatment of myasthenia and as a fluorescent probe in HPLC.
guanidine : An aminocarboxamidine, the parent compound of the guanidines.
Leukemia: A progressive, malignant disease of the blood-forming organs, characterized by distorted proliferation and development of leukocytes and their precursors in the blood and bone marrow. Leukemias were originally termed acute or chronic based on life expectancy but now are classified according to cellular maturity. Acute leukemias consist of predominately immature cells; chronic leukemias are composed of more mature cells. (From The Merck Manual, 2006)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Amet, R | 1 |
| Previtali, V | 1 |
| Mihigo, HB | 1 |
| Sheridan, E | 1 |
| Brophy, S | 1 |
| Hante, NK | 1 |
| Santos-Martinez, MJ | 1 |
| Hayden, PJ | 1 |
| Browne, PV | 1 |
| Rozas, I | 1 |
| McElligott, AM | 1 |
| Zisterer, DM | 1 |
| BURCHENAL, JH | 1 |
| PURPLE, JR | 1 |
| BUCHOLZ, E | 1 |
| STRAUB, PW | 1 |
| Shammas, C | 1 |
| Menne, TF | 1 |
| Hilcenko, C | 1 |
| Michell, SR | 1 |
| Goyenechea, B | 1 |
| Boocock, GR | 1 |
| Durie, PR | 1 |
| Rommens, JM | 1 |
| Warren, AJ | 1 |
| Gamliel, H | 1 |
| Gurfel, D | 1 |
| Leizerowitz, R | 1 |
| Polliack, A | 1 |
4 other studies available for guanidine and Leukemia
| Article | Year |
|---|---|
A novel aryl-guanidinium derivative, VP79s, targets the signal transducer and activator of transcription 3 signaling pathway, downregulates myeloid cell leukaemia-1 and exhibits preclinical activity against multiple myeloma.
Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Survival; Gene Expression; Gene Expression | 2022 |
Potentiation of methylglyoxal bis(guanylhydrazone) by stilbamidine in transplanted mouse leukemia.
Topics: Animals; Antineoplastic Agents; Guanidine; Guanidines; Leukemia; Leukemia, Experimental; Mice; Mitog | 1963 |
Structural and mutational analysis of the SBDS protein family. Insight into the leukemia-associated Shwachman-Diamond Syndrome.
Topics: Alleles; Amino Acid Sequence; Archaeoglobus fulgidus; Blotting, Western; Cell Cycle; Crystallography | 2005 |
Air-drying of human leucocytes for scanning electron microscopy using the GTGO procedure.
Topics: Freeze Drying; Glutaral; Guanidine; Guanidines; Humans; Hydrolyzable Tannins; Leukemia; Leukocytes; | 1983 |