guanidine has been researched along with Herpes Simplex in 2 studies
Guanidine: A strong organic base existing primarily as guanidium ions at physiological pH. It is found in the urine as a normal product of protein metabolism. It is also used in laboratory research as a protein denaturant. (From Martindale, the Extra Pharmacopoeia, 30th ed and Merck Index, 12th ed) It is also used in the treatment of myasthenia and as a fluorescent probe in HPLC.
guanidine : An aminocarboxamidine, the parent compound of the guanidines.
Herpes Simplex: A group of acute infections caused by herpes simplex virus type 1 or type 2 that is characterized by the development of one or more small fluid-filled vesicles with a raised erythematous base on the skin or mucous membrane. It occurs as a primary infection or recurs due to a reactivation of a latent infection. (Dorland, 27th ed.)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Current therapy against herpes simplex viruses (HSV) relies on the use of a few nucleoside antivirals such as acyclovir, famciclovir and valacyclovir." | 8.02 | Synthesis and Biological Evaluation of Amidinourea Derivatives against Herpes Simplex Viruses. ( Anselmi, S; Biolatti, M; Castagnolo, D; Dell'Oste, V; Denaro, R; Pacheco, SFC; Toscani, A, 2021) |
| "Current therapy against herpes simplex viruses (HSV) relies on the use of a few nucleoside antivirals such as acyclovir, famciclovir and valacyclovir." | 4.02 | Synthesis and Biological Evaluation of Amidinourea Derivatives against Herpes Simplex Viruses. ( Anselmi, S; Biolatti, M; Castagnolo, D; Dell'Oste, V; Denaro, R; Pacheco, SFC; Toscani, A, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 2 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, W | 1 |
| Xu, C | 1 |
| Zhang, J | 1 |
| Wang, J | 1 |
| Yu, R | 1 |
| Wang, D | 1 |
| Yin, R | 1 |
| Li, W | 1 |
| Jiang, T | 1 |
| Toscani, A | 1 |
| Denaro, R | 1 |
| Pacheco, SFC | 1 |
| Biolatti, M | 1 |
| Anselmi, S | 1 |
| Dell'Oste, V | 1 |
| Castagnolo, D | 1 |
2 other studies available for guanidine and Herpes Simplex
| Article | Year |
|---|---|
Guanidine modifications enhance the anti-herpes simplex virus activity of (E,E)-4,6-bis(styryl)-pyrimidine derivatives in vitro and in vivo.
Topics: Animals; Antiviral Agents; Guanidine; Guanidines; Herpes Simplex; Herpesvirus 1, Human; Herpesvirus | 2020 |
Synthesis and Biological Evaluation of Amidinourea Derivatives against Herpes Simplex Viruses.
Topics: Acyclovir; Antiviral Agents; Drug Resistance, Viral; Guanidine; Herpes Simplex; Herpesvirus 1, Human | 2021 |