guanidine has been researched along with Fibrosarcoma in 6 studies
Guanidine: A strong organic base existing primarily as guanidium ions at physiological pH. It is found in the urine as a normal product of protein metabolism. It is also used in laboratory research as a protein denaturant. (From Martindale, the Extra Pharmacopoeia, 30th ed and Merck Index, 12th ed) It is also used in the treatment of myasthenia and as a fluorescent probe in HPLC.
guanidine : An aminocarboxamidine, the parent compound of the guanidines.
Fibrosarcoma: A sarcoma derived from deep fibrous tissue, characterized by bundles of immature proliferating fibroblasts with variable collagen formation, which tends to invade locally and metastasize by the bloodstream. (Stedman, 25th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| " To accomplish this, rat fibrosarcoma cells were cultured in the presence of [3H]-acetate to isotopically label the hyaluronate, and then fixed with glutaraldehyde, which cross-links proteins but does not react directly with hyaluronate." | 3.67 | Hyaluronate appears to be covalently linked to the cell surface. ( Green, SJ; Underhill, CB, 1988) |
| " Similar results were obtained by measuring PAI-1 activity in plasma and with trace amounts of 125I-rPAI-1, suggesting that the above pharmacokinetic behavior could also apply to endogenous PAI-1." | 1.28 | The pharmacokinetics of plasminogen activator inhibitor-1 in the rabbit. ( Fujita, T; Gardell, SJ; Mayer, EJ; Reilly, CF; Shebuski, RJ, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (50.00) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barsoum, AL | 1 |
| Liu, B | 1 |
| Rohrer, JW | 1 |
| Coggin, JH | 1 |
| Tucker, JA | 1 |
| Pannell, LK | 1 |
| Schwarzenberger, PO | 1 |
| Okada, F | 1 |
| Tazawa, H | 1 |
| Kobayashi, T | 1 |
| Kobayashi, M | 1 |
| Hosokawa, M | 1 |
| Mayer, EJ | 1 |
| Fujita, T | 1 |
| Gardell, SJ | 1 |
| Shebuski, RJ | 1 |
| Reilly, CF | 1 |
| Lindahl, T | 1 |
| Wiman, B | 1 |
| Hettle, JA | 1 |
| Balekjian, E | 1 |
| Tung, PS | 1 |
| Fritz, IB | 1 |
| Green, SJ | 1 |
| Underhill, CB | 1 |
6 other studies available for guanidine and Fibrosarcoma
| Article | Year |
|---|---|
Production, safety and antitumor efficacy of recombinant Oncofetal Antigen/immature laminin receptor protein.
Topics: Amino Acid Sequence; Animals; Antigens, Neoplasm; Cancer Vaccines; Cell Line, Tumor; Clinical Trials | 2009 |
Involvement of reactive nitrogen oxides for acquisition of metastatic properties of benign tumors in a model of inflammation-based tumor progression.
Topics: Animals; Cell Movement; Cell Proliferation; Disease Progression; Female; Fibrosarcoma; Gelatin Spong | 2006 |
The pharmacokinetics of plasminogen activator inhibitor-1 in the rabbit.
Topics: Animals; Fibrosarcoma; Glycosylation; Guanidine; Guanidines; Half-Life; Humans; Metabolic Clearance | 1990 |
Purification of high and low molecular weight plasminogen activator inhibitor 1 from fibrosarcoma cell-line HT 1080 conditioned medium.
Topics: Amino Acid Sequence; Antibodies, Monoclonal; Chromatography, Affinity; Chromatography, Gel; Electrop | 1989 |
Rat testicular peritubular cells in culture secrete an inhibitor of plasminogen activator activity.
Topics: Animals; Bucladesine; Cattle; Cells, Cultured; Chromatography, Gel; Culture Media; Endothelium, Vasc | 1988 |
Hyaluronate appears to be covalently linked to the cell surface.
Topics: Animals; Cell Membrane; Chromatography, Gel; Cross-Linking Reagents; Detergents; Fibrosarcoma; Gluta | 1988 |