guanidine has been researched along with Eaton-Lambert Myasthenic Syndrome in 10 studies
Guanidine: A strong organic base existing primarily as guanidium ions at physiological pH. It is found in the urine as a normal product of protein metabolism. It is also used in laboratory research as a protein denaturant. (From Martindale, the Extra Pharmacopoeia, 30th ed and Merck Index, 12th ed) It is also used in the treatment of myasthenia and as a fluorescent probe in HPLC.
guanidine : An aminocarboxamidine, the parent compound of the guanidines.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Guanidine hydrochloride is known to be highly effective in the symptomatic treatment of the Lambert-Eaton myasthenic syndrome (LEMS)." | 9.08 | Low-dose guanidine and pyridostigmine: relatively safe and effective long-term symptomatic therapy in Lambert-Eaton myasthenic syndrome. ( Claussen, GC; Head, TC; Kim, DS; Oh, SJ, 1997) |
| "Guanidine hydrochloride is known to be highly effective in the symptomatic treatment of the Lambert-Eaton myasthenic syndrome (LEMS)." | 5.08 | Low-dose guanidine and pyridostigmine: relatively safe and effective long-term symptomatic therapy in Lambert-Eaton myasthenic syndrome. ( Claussen, GC; Head, TC; Kim, DS; Oh, SJ, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 7 (70.00) | 18.2507 |
| 2000's | 1 (10.00) | 29.6817 |
| 2010's | 2 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Oh, SJ | 3 |
| Maddison, P | 1 |
| Verschuuren, JJ | 1 |
| Wirtz, PW | 1 |
| Titulaer, MJ | 1 |
| Willems, LN | 1 |
| van Gerven, J | 1 |
| Kim, DS | 2 |
| Head, TC | 1 |
| Claussen, GC | 2 |
| Kwon, KH | 1 |
| Tseng, A | 1 |
| Mussell, H | 1 |
| Jost, WH | 1 |
| Mielke, U | 1 |
| Schimrigk, K | 1 |
| Engler, F | 1 |
| Lundh, H | 1 |
| Nilsson, O | 1 |
| Rosén, I | 1 |
| Silbert, PL | 1 |
| Hankey, GJ | 1 |
| Barr, AL | 1 |
| Sahashi, K | 1 |
5 reviews available for guanidine and Eaton-Lambert Myasthenic Syndrome
| Article | Year |
|---|---|
Amifampridine for the treatment of Lambert-Eaton myasthenic syndrome.
Topics: Amifampridine; Cholinesterase Inhibitors; Drug and Narcotic Control; Guanidine; Humans; Lambert-Eato | 2019 |
Treatment in Lambert-Eaton myasthenic syndrome.
Topics: 4-Aminopyridine; Amifampridine; Antineoplastic Agents; Guanidine; Humans; Immunoglobulins, Intraveno | 2012 |
Available treatment options for the management of Lambert-Eaton myasthenic syndrome.
Topics: 4-Aminopyridine; Antineoplastic Agents; Carcinoma, Small Cell; Cholinesterase Inhibitors; Cisplatin; | 2006 |
[Lambert-Eaton myasthenia syndrome--review with case report].
Topics: Autonomic Nervous System Diseases; Carcinoma, Small Cell; Guanidine; Guanidines; Humans; Lambert-Eat | 1990 |
Current therapy of the Lambert-Eaton myasthenic syndrome.
Topics: Aminopyridines; Guanidine; Guanidines; Humans; Immunosuppressive Agents; Immunotherapy; Lambert-Eato | 1990 |
1 trial available for guanidine and Eaton-Lambert Myasthenic Syndrome
| Article | Year |
|---|---|
Low-dose guanidine and pyridostigmine: relatively safe and effective long-term symptomatic therapy in Lambert-Eaton myasthenic syndrome.
Topics: Adult; Aged; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Electrophysiology; Female; | 1997 |
4 other studies available for guanidine and Eaton-Lambert Myasthenic Syndrome
| Article | Year |
|---|---|
Wide spectrum of symptomatic treatment in Lambert-Eaton myasthenic syndrome.
Topics: 4-Aminopyridine; Adult; Aged; Amifampridine; Carcinoma, Small Cell; Female; Guanidine; Humans; Lambe | 1998 |
Therapeutic approaches to Lambert-Eaton myasthenic syndrome in the intra-individual comparison.
Topics: 4-Aminopyridine; Amifampridine; Combined Modality Therapy; Electromyography; Follow-Up Studies; Guan | 1991 |
Successful alternate day guanidine therapy following guanidine-induced neutropenia in the Lambert-Eaton myasthenic syndrome.
Topics: Agranulocytosis; Drug Administration Schedule; Electromyography; Female; Guanidine; Guanidines; Huma | 1990 |
[Lambert-Eaton myasthenic syndrome].
Topics: 4-Aminopyridine; Adolescent; Adult; Aged; Amifampridine; Antibodies, Antinuclear; Child; Electromyog | 1990 |