guanidine has been researched along with Disseminated Fungal Infection in 2 studies
Guanidine: A strong organic base existing primarily as guanidium ions at physiological pH. It is found in the urine as a normal product of protein metabolism. It is also used in laboratory research as a protein denaturant. (From Martindale, the Extra Pharmacopoeia, 30th ed and Merck Index, 12th ed) It is also used in the treatment of myasthenia and as a fluorescent probe in HPLC.
guanidine : An aminocarboxamidine, the parent compound of the guanidines.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Invasive fungal infections have become an important healthcare issue due in large part to high mortality rates under standard of care (SOC) therapies creating an urgent need for new and effective anti-fungal agents." | 1.62 | Highly potent, broadly active antifungal agents for the treatment of invasive fungal infections. ( Baugh, SDP; Chaly, A; Freeman, KB; Pelletier, JC; Reitz, AB; Scott, RW; Thanna, S; Weaver, DG, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 2 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Baugh, SDP | 1 |
| Chaly, A | 1 |
| Weaver, DG | 1 |
| Pelletier, JC | 1 |
| Thanna, S | 1 |
| Freeman, KB | 1 |
| Reitz, AB | 1 |
| Scott, RW | 1 |
| Kato, I | 1 |
| Ukai, Y | 1 |
| Kondo, N | 1 |
| Nozu, K | 1 |
| Kimura, C | 1 |
| Hashimoto, K | 1 |
| Mizusawa, E | 1 |
| Maki, H | 1 |
| Naito, A | 1 |
| Kawai, M | 1 |
2 other studies available for guanidine and Disseminated Fungal Infection
| Article | Year |
|---|---|
Highly potent, broadly active antifungal agents for the treatment of invasive fungal infections.
Topics: Antifungal Agents; Aspergillus; Candida; Dose-Response Relationship, Drug; Guanidine; Invasive Funga | 2021 |
Identification of Thiazoyl Guanidine Derivatives as Novel Antifungal Agents Inhibiting Ergosterol Biosynthesis for Treatment of Invasive Fungal Infections.
Topics: Antifungal Agents; Aspergillus fumigatus; Dose-Response Relationship, Drug; Ergosterol; Guanidine; H | 2021 |