guanidine has been researched along with Coxsackie Virus Infections in 4 studies
Guanidine: A strong organic base existing primarily as guanidium ions at physiological pH. It is found in the urine as a normal product of protein metabolism. It is also used in laboratory research as a protein denaturant. (From Martindale, the Extra Pharmacopoeia, 30th ed and Merck Index, 12th ed) It is also used in the treatment of myasthenia and as a fluorescent probe in HPLC.
guanidine : An aminocarboxamidine, the parent compound of the guanidines.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Median effective dose was interpolated from the triplicated experiments and the dose-response curves were generated for each drug-virus combination." | 1.56 | A preclinical assessment to repurpose drugs to target type 1 diabetes-associated type B coxsackieviruses. ( Honkimaa, A; Hyöty, H; Sioofy-Khojine, AB, 2020) |
| "When guanidine was reduced to 48 mg/kg per injection, 34 mg/kg per injection of LY122771-72 was required to produce a significant reduction in the death rate and no tremors were observed." | 1.26 | Prevention of death in mice infected with coxsackievirus A16 using guanidine HCl mixed with substituted benzimidazoles. ( Delong, DC; Herrmann, EC; Herrmann, JA, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sioofy-Khojine, AB | 1 |
| Honkimaa, A | 1 |
| Hyöty, H | 1 |
| Stoyanova, A | 1 |
| Nikolova, I | 1 |
| Galabov, AS | 2 |
| Vassileva-Pencheva, R | 1 |
| Herrmann, EC | 1 |
| Herrmann, JA | 1 |
| Delong, DC | 1 |
4 other studies available for guanidine and Coxsackie Virus Infections
| Article | Year |
|---|---|
A preclinical assessment to repurpose drugs to target type 1 diabetes-associated type B coxsackieviruses.
Topics: A549 Cells; Amides; Antiviral Agents; Azithromycin; Benzimidazoles; Coxsackievirus Infections; Diabe | 2020 |
Effect of consecutive alternating administration (CAA) of a triple anti-enteroviral combination on Coxsackievirus B1 neuroinfection in mice.
Topics: Animals; Antiviral Agents; Apomorphine; Brain; Central Nervous System Infections; Coxsackievirus Inf | 2015 |
Effectiveness of the Consecutive Alternating Administration Course of a Triple Antiviral Combination in Coxsackievirus B3 Infections in Mice.
Topics: Animals; Animals, Newborn; Antiviral Agents; Apomorphine; Coxsackievirus Infections; Drug Therapy, C | 2016 |
Prevention of death in mice infected with coxsackievirus A16 using guanidine HCl mixed with substituted benzimidazoles.
Topics: Animals; Antiviral Agents; Benzimidazoles; Coxsackievirus Infections; Drug Combinations; Drug Synerg | 1982 |