Page last updated: 2024-10-28

guanidine and Choriocarcinoma

guanidine has been researched along with Choriocarcinoma in 1 studies

Guanidine: A strong organic base existing primarily as guanidium ions at physiological pH. It is found in the urine as a normal product of protein metabolism. It is also used in laboratory research as a protein denaturant. (From Martindale, the Extra Pharmacopoeia, 30th ed and Merck Index, 12th ed) It is also used in the treatment of myasthenia and as a fluorescent probe in HPLC.
guanidine : An aminocarboxamidine, the parent compound of the guanidines.

Choriocarcinoma: A malignant metastatic form of trophoblastic tumors. Unlike the HYDATIDIFORM MOLE, choriocarcinoma contains no CHORIONIC VILLI but rather sheets of undifferentiated cytotrophoblasts and syncytiotrophoblasts (TROPHOBLASTS). It is characterized by the large amounts of CHORIONIC GONADOTROPIN produced. Tissue origins can be determined by DNA analyses: placental (fetal) origin or non-placental origin (CHORIOCARCINOMA, NON-GESTATIONAL).

Research Excerpts

ExcerptRelevanceReference
" The aim of this study was to determine the mechanisms of organic cation transport using the human choriocarcinoma cell line (JAR) as a model system with [14C]guanidine as a ligand."7.69Guanidine transport in a human choriocarcinoma cell line (JAR). ( Giacomini, KM; Illsley, NP; Schaner, ME; Zevin, S, 1997)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Zevin, S1
Schaner, ME1
Illsley, NP1
Giacomini, KM1

Other Studies

1 other study available for guanidine and Choriocarcinoma

ArticleYear
Guanidine transport in a human choriocarcinoma cell line (JAR).
    Pharmaceutical research, 1997, Volume: 14, Issue:4

    Topics: Biological Transport; Carbon Radioisotopes; Choriocarcinoma; Guanidine; Guanidines; Humans; Kinetics

1997