guanidine has been researched along with Chagas Disease in 1 studies
Guanidine: A strong organic base existing primarily as guanidium ions at physiological pH. It is found in the urine as a normal product of protein metabolism. It is also used in laboratory research as a protein denaturant. (From Martindale, the Extra Pharmacopoeia, 30th ed and Merck Index, 12th ed) It is also used in the treatment of myasthenia and as a fluorescent probe in HPLC.
guanidine : An aminocarboxamidine, the parent compound of the guanidines.
Chagas Disease: Infection with the protozoan parasite TRYPANOSOMA CRUZI, a form of TRYPANOSOMIASIS endemic in Central and South America. It is named after the Brazilian physician Carlos Chagas, who discovered the parasite. Infection by the parasite (positive serologic result only) is distinguished from the clinical manifestations that develop years later, such as destruction of PARASYMPATHETIC GANGLIA; CHAGAS CARDIOMYOPATHY; and dysfunction of the ESOPHAGUS or COLON.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Chagas' disease is an important parasitic illness caused by the flagellated protozoan Trypanosoma cruzi." | 1.34 | Activity of "reversed" diamidines against Trypanosoma cruzi "in vitro". ( Batista, MM; Boykin, DW; de Souza, EM; Mota, RA; Silva, CF; Soeiro, Mde N; Som, P; Stephens, CE, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Silva, CF | 1 |
| Batista, MM | 1 |
| Mota, RA | 1 |
| de Souza, EM | 1 |
| Stephens, CE | 1 |
| Som, P | 1 |
| Boykin, DW | 1 |
| Soeiro, Mde N | 1 |
1 other study available for guanidine and Chagas Disease
| Article | Year |
|---|---|
Activity of "reversed" diamidines against Trypanosoma cruzi "in vitro".
Topics: Animals; Chagas Disease; Chlorocebus aethiops; Dose-Response Relationship, Drug; Furans; Guanidine; | 2007 |