guanidine has been researched along with Cataract, Membranous in 7 studies
Guanidine: A strong organic base existing primarily as guanidium ions at physiological pH. It is found in the urine as a normal product of protein metabolism. It is also used in laboratory research as a protein denaturant. (From Martindale, the Extra Pharmacopoeia, 30th ed and Merck Index, 12th ed) It is also used in the treatment of myasthenia and as a fluorescent probe in HPLC.
guanidine : An aminocarboxamidine, the parent compound of the guanidines.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Cataract is a lens opacification disease prevalent worldwide." | 1.42 | Congenital Cataract-Causing Mutation G129C in γC-Crystallin Promotes the Accumulation of Two Distinct Unfolding Intermediates That Form Highly Toxic Aggregates. ( Chen, XJ; Xi, YB; Yan, YB; Zhao, WJ, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (42.86) | 29.6817 |
| 2010's | 2 (28.57) | 24.3611 |
| 2020's | 2 (28.57) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, H | 2 |
| Tian, Q | 1 |
| Xu, J | 3 |
| Xu, W | 1 |
| Yao, K | 2 |
| Chen, X | 2 |
| Wu, C | 1 |
| Wang, A | 1 |
| Wu, W | 1 |
| Luo, C | 1 |
| Ni, S | 1 |
| Xi, YB | 1 |
| Chen, XJ | 1 |
| Zhao, WJ | 1 |
| Yan, YB | 2 |
| Ma, Z | 1 |
| Piszczek, G | 1 |
| Wingfield, PT | 1 |
| Sergeev, YV | 1 |
| Hejtmancik, JF | 1 |
| Pang, M | 1 |
| Su, JT | 1 |
| Feng, S | 1 |
| Tang, ZW | 1 |
| Gu, F | 1 |
| Zhang, M | 1 |
| Ma, X | 1 |
| Meehan, S | 1 |
| Berry, Y | 1 |
| Luisi, B | 1 |
| Dobson, CM | 1 |
| Carver, JA | 1 |
| MacPhee, CE | 1 |
| Evans, P | 1 |
| Wyatt, K | 1 |
| Wistow, GJ | 1 |
| Bateman, OA | 1 |
| Wallace, BA | 1 |
| Slingsby, C | 1 |
7 other studies available for guanidine and Cataract, Membranous
| Article | Year |
|---|---|
Cataract-causing G91del mutant destabilised βA3 heteromers formation linking with structural stability and cellular viability.
Topics: beta-Crystallin A Chain; Cataract; Crystallins; Glycine; Guanidine; Humans; Lens, Crystalline | 2022 |
Pathogenic mechanism of congenital cataract caused by the CRYBA1/A3-G91del variant and related intervention strategies.
Topics: Apoptosis; beta-Crystallin A Chain; Cataract; Cell Line; Genetic Predisposition to Disease; Guanidin | 2021 |
Congenital Cataract-Causing Mutation G129C in γC-Crystallin Promotes the Accumulation of Two Distinct Unfolding Intermediates That Form Highly Toxic Aggregates.
Topics: Amyloid; Apoptosis; Cataract; Cell Line, Tumor; Cell Proliferation; gamma-Crystallins; Guanidine; He | 2015 |
The G18V CRYGS mutation associated with human cataracts increases gammaS-crystallin sensitivity to thermal and chemical stress.
Topics: Cataract; Circular Dichroism; gamma-Crystallins; Guanidine; Hot Temperature; Humans; Lens, Crystalli | 2009 |
Effects of congenital cataract mutation R116H on alphaA-crystallin structure, function and stability.
Topics: Amino Acid Substitution; Cataract; Circular Dichroism; Crystallins; Guanidine; Humans; In Vitro Tech | 2010 |
Amyloid fibril formation by lens crystallin proteins and its implications for cataract formation.
Topics: Aging; alpha-Crystallins; Amyloid; Animals; Benzothiazoles; beta-Crystallins; Cataract; Cattle; Dose | 2004 |
The P23T cataract mutation causes loss of solubility of folded gammaD-crystallin.
Topics: Amino Acid Sequence; Animals; Cataract; Circular Dichroism; gamma-Crystallins; Guanidine; Humans; Mo | 2004 |