Page last updated: 2024-10-28

guanidine and Cancer of Prostate

guanidine has been researched along with Cancer of Prostate in 4 studies

Guanidine: A strong organic base existing primarily as guanidium ions at physiological pH. It is found in the urine as a normal product of protein metabolism. It is also used in laboratory research as a protein denaturant. (From Martindale, the Extra Pharmacopoeia, 30th ed and Merck Index, 12th ed) It is also used in the treatment of myasthenia and as a fluorescent probe in HPLC.
guanidine : An aminocarboxamidine, the parent compound of the guanidines.

Research Excerpts

ExcerptRelevanceReference
"Nanog downregulation in prostate cancer cell line DU145 in serum containing media led to suppression of associated proteins such as KLF4, FAK and cMyc and also enhanced the chemosensitivity of Epirubicin, an anthracycline based drug, in DU145 cells by associated MDR-1 downregulation in vitro."1.72IGT mediated Nanog siRNA delivery in prostate cancer cells improves chemosensitization of Epirubicin in vitro. ( Das, U; Gupta, S; Sinha, S, 2022)
"Moreover, AR mutants in complete androgen insensitivity syndrome (CAIS) tend to have a greater effect on protein stability than in partial androgen insensitive syndrome (PAIS)."1.56Computational analysis of androgen receptor (AR) variants to decipher the relationship between protein stability and related-diseases. ( Chen, F; Chen, X; Gui, Y; Jiang, F; Leng, F; Liu, W; Yu, J, 2020)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's4 (100.00)2.80

Authors

AuthorsStudies
Gupta, S1
Das, U1
Sinha, S1
Dyshlovoy, SA1
Shubina, LK1
Makarieva, TN1
Guzii, AG1
Hauschild, J1
Strewinsky, N1
Berdyshev, DV1
Kudryashova, EK1
Menshov, AS1
Popov, RS1
Dmitrenok, PS1
Graefen, M1
Bokemeyer, C1
von Amsberg, G1
Killian, C1
Johnson, SL1
Ma, H1
McKeown, B1
McDougall, L1
Hurta, R1
Liu, Y1
Seeram, NP1
Chen, F1
Chen, X1
Jiang, F1
Leng, F1
Liu, W1
Gui, Y1
Yu, J1

Other Studies

4 other studies available for guanidine and Cancer of Prostate

ArticleYear
IGT mediated Nanog siRNA delivery in prostate cancer cells improves chemosensitization of Epirubicin in vitro.
    Bioorganic & medicinal chemistry letters, 2022, 11-15, Volume: 76

    Topics: Cell Line, Tumor; Drug Resistance, Neoplasm; Epirubicin; Guanidine; Humans; Male; Morpholinos; Nanog

2022
New Guanidine Alkaloids Batzelladines O and P from the Marine Sponge
    Marine drugs, 2022, Nov-25, Volume: 20, Issue:12

    Topics: Alkaloids; Animals; Antineoplastic Agents; Apoptosis; Autophagy; Cell Line, Tumor; Docetaxel; Guanid

2022
Celosiadines A and B, unusual guanidine alkaloids from
    Natural product research, 2022, Volume: 36, Issue:1

    Topics: Alkaloids; Amaranthaceae; Cell Line, Tumor; Guanidine; Guanidines; Humans; Male; Prostatic Neoplasms

2022
Computational analysis of androgen receptor (AR) variants to decipher the relationship between protein stability and related-diseases.
    Scientific reports, 2020, 07-21, Volume: 10, Issue:1

    Topics: Androgen-Insensitivity Syndrome; Computational Biology; Databases, Genetic; Genetic Association Stud

2020