guanidine has been researched along with Cancer of Ovary in 3 studies
Guanidine: A strong organic base existing primarily as guanidium ions at physiological pH. It is found in the urine as a normal product of protein metabolism. It is also used in laboratory research as a protein denaturant. (From Martindale, the Extra Pharmacopoeia, 30th ed and Merck Index, 12th ed) It is also used in the treatment of myasthenia and as a fluorescent probe in HPLC.
guanidine : An aminocarboxamidine, the parent compound of the guanidines.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Carriers of germ line mutations in breast cancer susceptibility gene BRCA1 have an increased risk of developing breast and ovarian cancers; missense mutations have, however, been difficult to assess for disease association." | 1.36 | Toward classification of BRCA1 missense variants using a biophysical approach. ( Cook, R; Itzhaki, LS; Rowling, PJ, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Vargas, JR | 1 |
| Stanzl, EG | 1 |
| Teng, NN | 1 |
| Wender, PA | 1 |
| Rowling, PJ | 1 |
| Cook, R | 1 |
| Itzhaki, LS | 1 |
| Modrzejewska, H | 1 |
| Brzezińska, E | 1 |
| Dramiński, M | 1 |
| Zgit-Wróblewska, A | 1 |
| Krzykowska, K | 1 |
| Rozpończyk, E | 1 |
| Greger, J | 1 |
1 review available for guanidine and Cancer of Ovary
| Article | Year |
|---|---|
Cell-penetrating, guanidinium-rich molecular transporters for overcoming efflux-mediated multidrug resistance.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Cell Line, T | 2014 |
2 other studies available for guanidine and Cancer of Ovary
| Article | Year |
|---|---|
Toward classification of BRCA1 missense variants using a biophysical approach.
Topics: Algorithms; Binding Sites; BRCA1 Protein; Breast Neoplasms; Escherichia coli; Female; Fluorescence P | 2010 |
A study of the influence of newly synthesized acyclonucleosides and 1,2,3,4-tetrahydroisoquinoline derivatives on deoxythymidine and deoxycytidine kinase activities in human neurofibrosarcoma and ovarian cancer.
Topics: Carbon Radioisotopes; Deoxycytidine Kinase; Female; Guanidine; Humans; Kinetics; Neurofibrosarcoma; | 2003 |