guanidine has been researched along with Botulism in 2 studies
Guanidine: A strong organic base existing primarily as guanidium ions at physiological pH. It is found in the urine as a normal product of protein metabolism. It is also used in laboratory research as a protein denaturant. (From Martindale, the Extra Pharmacopoeia, 30th ed and Merck Index, 12th ed) It is also used in the treatment of myasthenia and as a fluorescent probe in HPLC.
guanidine : An aminocarboxamidine, the parent compound of the guanidines.
Botulism: A disease caused by potent protein NEUROTOXINS produced by CLOSTRIDIUM BOTULINUM which interfere with the presynaptic release of ACETYLCHOLINE at the NEUROMUSCULAR JUNCTION. Clinical features include abdominal pain, vomiting, acute PARALYSIS (including respiratory paralysis), blurred vision, and DIPLOPIA. Botulism may be classified into several subtypes (e.g., food-borne, infant, wound, and others). (From Adams et al., Principles of Neurology, 6th ed, p1208)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Botulism is induced by botulinum toxin and the mechanism of the disease is unknown." | 1.27 | The mechanism of botulism. ( Chao, LP, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Roblot, P | 1 |
| Roblot, F | 1 |
| Fauchère, JL | 1 |
| Devilleger, A | 1 |
| Maréchaud, R | 1 |
| Breux, JP | 1 |
| Grollier, G | 1 |
| Becq-Giraudon, B | 1 |
| Chao, LP | 1 |
2 other studies available for guanidine and Botulism
| Article | Year |
|---|---|
Retrospective study of 108 cases of botulism in Poitiers, France.
Topics: Adolescent; Adult; Aged; Animals; Botulinum Antitoxin; Botulinum Toxins; Botulism; Child; Child, Pre | 1994 |
The mechanism of botulism.
Topics: Animals; Autoimmune Diseases; Botulinum Toxins; Botulism; Choline O-Acetyltransferase; Enzyme Activa | 1986 |