guanidine has been researched along with Benign Neoplasms in 17 studies
Guanidine: A strong organic base existing primarily as guanidium ions at physiological pH. It is found in the urine as a normal product of protein metabolism. It is also used in laboratory research as a protein denaturant. (From Martindale, the Extra Pharmacopoeia, 30th ed and Merck Index, 12th ed) It is also used in the treatment of myasthenia and as a fluorescent probe in HPLC.
guanidine : An aminocarboxamidine, the parent compound of the guanidines.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Guanidine hydrochloride is known to be highly effective in the symptomatic treatment of the Lambert-Eaton myasthenic syndrome (LEMS)." | 9.08 | Low-dose guanidine and pyridostigmine: relatively safe and effective long-term symptomatic therapy in Lambert-Eaton myasthenic syndrome. ( Claussen, GC; Head, TC; Kim, DS; Oh, SJ, 1997) |
| "Guanidine hydrochloride is known to be highly effective in the symptomatic treatment of the Lambert-Eaton myasthenic syndrome (LEMS)." | 5.08 | Low-dose guanidine and pyridostigmine: relatively safe and effective long-term symptomatic therapy in Lambert-Eaton myasthenic syndrome. ( Claussen, GC; Head, TC; Kim, DS; Oh, SJ, 1997) |
| "Out of 11 human cancer cell lines tested, GPL significantly inhibited proliferation of five lines viz." | 1.34 | Characterization of a lectin from Gonatanthus pumilus D. Don having anti-proliferative effect against human cancer cell lines. ( Bhide, SV; Dhuna, V; Kamboj, SS; Kaur, A; Saxena, AK; Singh, J, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (5.88) | 18.7374 |
| 1990's | 1 (5.88) | 18.2507 |
| 2000's | 3 (17.65) | 29.6817 |
| 2010's | 6 (35.29) | 24.3611 |
| 2020's | 6 (35.29) | 2.80 |
| Authors | Studies |
|---|---|
| Xu, H | 2 |
| Chang, J | 1 |
| Wu, H | 1 |
| Wang, H | 1 |
| Xie, W | 1 |
| Li, Y | 2 |
| Li, X | 2 |
| Zhang, Y | 1 |
| Fan, L | 1 |
| Xu, X | 1 |
| Wang, R | 1 |
| Li, D | 1 |
| Xiang, J | 1 |
| Zhang, W | 1 |
| Shi, X | 1 |
| Yao, S | 1 |
| Liu, J | 1 |
| Shao, S | 1 |
| Zhou, Z | 1 |
| Huang, F | 1 |
| Shen, Y | 1 |
| Tang, J | 1 |
| Gomes, AR | 1 |
| Varela, CL | 1 |
| Pires, AS | 1 |
| Tavares-da-Silva, EJ | 1 |
| Roleira, FMF | 1 |
| Del Campo-Balguerías, A | 1 |
| Parra-Cadenas, B | 1 |
| Nieto-Jimenez, C | 1 |
| Bravo, I | 1 |
| Ripoll, C | 1 |
| Poyatos-Racionero, E | 1 |
| Gancarski, P | 1 |
| Carrillo-Hermosilla, F | 1 |
| Alonso-Moreno, C | 1 |
| Ocaña, A | 1 |
| Dang, J | 1 |
| Ye, H | 1 |
| Liang, Q | 1 |
| Yin, L | 1 |
| Thomas, SJ | 1 |
| Balónová, B | 1 |
| Cinatl, J | 1 |
| Wass, MN | 1 |
| Serpell, CJ | 1 |
| Blight, BA | 1 |
| Michaelis, M | 1 |
| Cho, H | 1 |
| Cho, YY | 1 |
| Shim, MS | 1 |
| Lee, JY | 1 |
| Lee, HS | 1 |
| Kang, HC | 1 |
| Johansen, ML | 1 |
| Gao, Y | 1 |
| Hutnick, MA | 1 |
| Craig, SEL | 1 |
| Pokorski, JK | 1 |
| Flask, CA | 1 |
| Brady-Kalnay, SM | 1 |
| Brancaccio, D | 1 |
| Diana, D | 1 |
| Di Maro, S | 1 |
| Di Leva, FS | 1 |
| Tomassi, S | 1 |
| Fattorusso, R | 1 |
| Russo, L | 1 |
| Scala, S | 1 |
| Trotta, AM | 1 |
| Portella, L | 1 |
| Novellino, E | 1 |
| Marinelli, L | 1 |
| Carotenuto, A | 1 |
| Legin, AA | 1 |
| Jakupec, MA | 1 |
| Bokach, NA | 1 |
| Tyan, MR | 1 |
| Kukushkin, VY | 1 |
| Keppler, BK | 1 |
| Sidoryk, K | 1 |
| Świtalska, M | 1 |
| Jaromin, A | 1 |
| Cmoch, P | 1 |
| Bujak, I | 1 |
| Kaczmarska, M | 1 |
| Wietrzyk, J | 1 |
| Dominguez, EG | 1 |
| Żarnowski, R | 1 |
| Andes, DR | 1 |
| Bańkowski, K | 1 |
| Cybulski, M | 1 |
| Kaczmarek, Ł | 1 |
| Nair, JB | 1 |
| Joseph, MM | 1 |
| Mohapatra, S | 1 |
| Safeera, M | 1 |
| Ghosh, S | 1 |
| Sreelekha, TT | 1 |
| Maiti, KK | 1 |
| Lee, AS | 1 |
| Galea, C | 1 |
| DiGiammarino, EL | 1 |
| Jun, B | 1 |
| Murti, G | 1 |
| Ribeiro, RC | 1 |
| Zambetti, G | 1 |
| Schultz, CP | 1 |
| Kriwacki, RW | 1 |
| BAIOCCHI, F | 1 |
| CHENG, CC | 1 |
| HAGGERTY, WJ | 1 |
| LEWIS, LR | 1 |
| LIAO, TK | 1 |
| NYBERG, WH | 1 |
| O'BRIEN, DE | 1 |
| PODREBARAC, EG | 1 |
| Robertson, N | 1 |
| Leek, R | 1 |
| Dhuna, V | 1 |
| Kamboj, SS | 1 |
| Kaur, A | 1 |
| Saxena, AK | 1 |
| Bhide, SV | 1 |
| Singh, J | 1 |
| Oh, SJ | 1 |
| Kim, DS | 1 |
| Head, TC | 1 |
| Claussen, GC | 1 |
2 reviews available for guanidine and Benign Neoplasms
| Article | Year |
|---|---|
Synthetic and natural guanidine derivatives as antitumor and antimicrobial agents: A review.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Antihypertensive Agents; Antineoplastic Agents; Antivi | 2023 |
Mitochondria-targeted drug delivery in cancers.
Topics: Animals; Antineoplastic Agents; Drug Delivery Systems; Glutathione; Guanidine; Humans; Hydrogen-Ion | 2020 |
1 trial available for guanidine and Benign Neoplasms
| Article | Year |
|---|---|
Low-dose guanidine and pyridostigmine: relatively safe and effective long-term symptomatic therapy in Lambert-Eaton myasthenic syndrome.
Topics: Adult; Aged; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Electrophysiology; Female; | 1997 |
14 other studies available for guanidine and Benign Neoplasms
| Article | Year |
|---|---|
Carbon Dots with Guanidinium and Amino Acid Functional Groups for Targeted Small Interfering RNA Delivery toward Tumor Gene Therapy.
Topics: Amino Acids; Carbon; Genetic Therapy; Guanidine; Humans; Methadyl Acetate; Neoplasms; RNA, Small Int | 2023 |
Guanidine-modified nanoparticles as robust BTZ delivery carriers and activators of immune responses.
Topics: Antigens; Bortezomib; Cell Line, Tumor; Drug Carriers; Guanidine; Humans; Immunity; Immunotherapy; N | 2023 |
Guanylation Reactions for the Rational Design of Cancer Therapeutic Agents.
Topics: Apoptosis; Cell Death; Guanidine; Guanidines; Humans; Neoplasms | 2023 |
Multivalency-assisted membrane-penetrating siRNA delivery sensitizes photothermal ablation via inhibition of tumor glycolysis metabolism.
Topics: Animals; Antineoplastic Agents; Apoptosis; Carrier Proteins; Cell Line, Tumor; Drug Delivery Systems | 2019 |
Thiourea and Guanidine Compounds and Their Iridium Complexes in Drug-Resistant Cancer Cell Lines: Structure-Activity Relationships and Direct Luminescent Imaging.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Coordination Complexes; Dose-Response R | 2020 |
Quantitative Molecular Imaging with a Single Gd-Based Contrast Agent Reveals Specific Tumor Binding and Retention in Vivo.
Topics: Animals; Contrast Media; Glioma; Guanidine; Heterografts; Humans; Mice; Molecular Imaging; Neoplasms | 2017 |
Ligand-Based NMR Study of C-X-C Chemokine Receptor Type 4 (CXCR4)-Ligand Interactions on Living Cancer Cells.
Topics: Animals; Cell Line; Cell Line, Tumor; Cell Survival; Chemokine CXCL12; Cricetinae; Cricetulus; Epito | 2018 |
Guanidine platinum(II) complexes: synthesis, in vitro antitumor activity, and DNA interactions.
Topics: Antineoplastic Agents; Cell Line, Tumor; DNA; Guanidine; Humans; Ligands; Molecular Structure; Neopl | 2014 |
The synthesis of indolo[2,3-b]quinoline derivatives with a guanidine group: highly selective cytotoxic agents.
Topics: Antifungal Agents; Apoptosis; Biofilms; Candida albicans; Caspases; Cell Line, Tumor; Cell Prolifera | 2015 |
A Dual-Targeting Octaguanidine-Doxorubicin Conjugate Transporter for Inducing Caspase-Mediated Apoptosis on Folate-Expressing Cancer Cells.
Topics: Animals; Antibiotics, Antineoplastic; Apoptosis; Caspases; Cell Proliferation; Dose-Response Relatio | 2016 |
Reversible amyloid formation by the p53 tetramerization domain and a cancer-associated mutant.
Topics: Amyloid; Benzothiazoles; Circular Dichroism; Coloring Agents; Congo Red; Dose-Response Relationship, | 2003 |
STUDIES ON METHYLGLYOXAL BIS(GUANYLHYDRAZONE) ANALOGS. II. STRUCTURAL VARIATIONS ON METHYLGLYOXAL BIS(GUANYLHYDRAZONE).
Topics: Antineoplastic Agents; Chemistry, Pharmaceutical; Guanidine; Guanidines; Mitoguazone; Neoplasms; Neo | 1963 |
Isolation of RNA from tumor samples: single-step guanidinium acid-phenol method.
Topics: Guanidine; Humans; Neoplasms; Phenols; RNA, Neoplasm | 2006 |
Characterization of a lectin from Gonatanthus pumilus D. Don having anti-proliferative effect against human cancer cell lines.
Topics: Antifungal Agents; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Guanidine; Humans; I | 2007 |