guanidine has been researched along with Amyloidosis in 10 studies
Guanidine: A strong organic base existing primarily as guanidium ions at physiological pH. It is found in the urine as a normal product of protein metabolism. It is also used in laboratory research as a protein denaturant. (From Martindale, the Extra Pharmacopoeia, 30th ed and Merck Index, 12th ed) It is also used in the treatment of myasthenia and as a fluorescent probe in HPLC.
guanidine : An aminocarboxamidine, the parent compound of the guanidines.
Amyloidosis: A group of sporadic, familial and/or inherited, degenerative, and infectious disease processes, linked by the common theme of abnormal protein folding and deposition of AMYLOID. As the amyloid deposits enlarge they displace normal tissue structures, causing disruption of function. Various signs and symptoms depend on the location and size of the deposits.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Potassium permanganate reaction, immunohistochemical assay using immune sera, and autoclave method combined with alkaline guanidine one are considered to be the most effective methods among those designed for verifying forms (primary, secondary, hereditary, senile systemic) of systemic amyloidosis." | 3.67 | [Methods for verifying forms of amyloidosis by a pathologist]. ( Zykova, LD, 1989) |
| "The immunoperoxidase method, the autoclave method, and a newly developed alkaline-guanidine method were used to distinguish senile (SSA) and familial types (FAP) of prealbumin-related amyloidosis in formalin-fixed, paraffin-embedded tissue sections." | 3.67 | Novel histochemical approaches to the prealbumin-related senile and familial forms of systemic amyloidosis. ( Kitamoto, T; Tashima, T; Tateishi, J, 1986) |
| "Betaine was more effective than sorbitol." | 1.31 | Counteracting effects of renal solutes on amyloid fibril formation by immunoglobulin light chains. ( Cape, SP; Carpenter, JF; Chi, E; Kim, YS; Manning, MC; Raffen, R; Randolph, TW; Solomon, A; Stevens, FJ; Wilkins-Stevens, P, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (20.00) | 18.7374 |
| 1990's | 1 (10.00) | 18.2507 |
| 2000's | 7 (70.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Esposito, G | 1 |
| Garcia, J | 1 |
| Mangione, P | 1 |
| Giorgetti, S | 1 |
| Corazza, A | 1 |
| Viglino, P | 1 |
| Chiti, F | 1 |
| Andreola, A | 1 |
| Dumy, P | 1 |
| Booth, D | 1 |
| Hawkins, PN | 1 |
| Bellotti, V | 1 |
| Narimoto, T | 1 |
| Sakurai, K | 1 |
| Okamoto, A | 1 |
| Chatani, E | 1 |
| Hoshino, M | 1 |
| Hasegawa, K | 1 |
| Naiki, H | 1 |
| Goto, Y | 1 |
| Zhang, H | 1 |
| Sawashita, J | 1 |
| Fu, X | 1 |
| Korenaga, T | 1 |
| Yan, J | 1 |
| Mori, M | 1 |
| Higuchi, K | 1 |
| Mazhul', VM | 1 |
| Zaĭtseva, EM | 1 |
| Shavlovskiĭ, MM | 1 |
| Povarova, OI | 1 |
| Kuznetsova, IM | 1 |
| Turoverov, KK | 1 |
| Kim, YS | 1 |
| Cape, SP | 1 |
| Chi, E | 1 |
| Raffen, R | 1 |
| Wilkins-Stevens, P | 1 |
| Stevens, FJ | 1 |
| Manning, MC | 1 |
| Randolph, TW | 1 |
| Solomon, A | 1 |
| Carpenter, JF | 1 |
| Hammarström, P | 1 |
| Jiang, X | 1 |
| Deechongkit, S | 1 |
| Kelly, JW | 1 |
| Galani, D | 1 |
| Fersht, AR | 1 |
| Perrett, S | 1 |
| Nelson, SR | 1 |
| Lyon, M | 1 |
| Gallagher, JT | 1 |
| Johnson, EA | 1 |
| Pepys, MB | 1 |
| Zykova, LD | 1 |
| Kitamoto, T | 1 |
| Tashima, T | 1 |
| Tateishi, J | 1 |
10 other studies available for guanidine and Amyloidosis
| Article | Year |
|---|---|
Structural and folding dynamic properties of the T70N variant of human lysozyme.
Topics: Alleles; Amyloid; Amyloidosis; Catalysis; Circular Dichroism; Crystallography, X-Ray; Dose-Response | 2003 |
Conformational stability of amyloid fibrils of beta2-microglobulin probed by guanidine-hydrochloride-induced unfolding.
Topics: Ammonium Sulfate; Amyloidosis; beta 2-Microglobulin; Guanidine; Humans; Protein Conformation; Protei | 2004 |
Transmissibility of mouse AApoAII amyloid fibrils: inactivation by physical and chemical methods.
Topics: Amyloid; Amyloidosis; Animals; Apolipoprotein A-II; Formates; Guanidine; Mice; Mice, Mutant Strains; | 2006 |
[Room temperature phosphorescence of amorphous aggregates and amyloid fibrils resulting from protein misfolding].
Topics: Actins; Amyloid; Amyloidosis; Animals; Cattle; Guanidine; Insulin; Kinetics; Lactalbumin; Luminescen | 2005 |
Counteracting effects of renal solutes on amyloid fibril formation by immunoglobulin light chains.
Topics: Amyloid; Amyloidosis; Betaine; Chromatography, High Pressure Liquid; Guanidine; Humans; Immunoglobul | 2001 |
Anion shielding of electrostatic repulsions in transthyretin modulates stability and amyloidosis: insight into the chaotrope unfolding dichotomy.
Topics: Amino Acid Substitution; Amyloid; Amyloidosis; Anions; Binding Sites; Cross-Linking Reagents; Drug S | 2001 |
Folding of the yeast prion protein Ure2: kinetic evidence for folding and unfolding intermediates.
Topics: Amyloidosis; Dimerization; Fluorescence; Glutathione Peroxidase; Guanidine; Isomerism; Kinetics; Mod | 2002 |
Isolation and characterization of the integral glycosaminoglycan constituents of human amyloid A and monoclonal light-chain amyloid fibrils.
Topics: Amyloidosis; Carbohydrate Sequence; Centrifugation, Density Gradient; Chemical Precipitation; Dermat | 1991 |
[Methods for verifying forms of amyloidosis by a pathologist].
Topics: Amyloidosis; Diagnosis, Differential; Guanidine; Guanidines; Humans; Immunohistochemistry; Potassium | 1989 |
Novel histochemical approaches to the prealbumin-related senile and familial forms of systemic amyloidosis.
Topics: Aged; Aging; Alkalies; Amyloidosis; Guanidine; Guanidines; Histocytochemistry; Humans; Immunochemist | 1986 |