guanidine has been researched along with Aging in 15 studies
Guanidine: A strong organic base existing primarily as guanidium ions at physiological pH. It is found in the urine as a normal product of protein metabolism. It is also used in laboratory research as a protein denaturant. (From Martindale, the Extra Pharmacopoeia, 30th ed and Merck Index, 12th ed) It is also used in the treatment of myasthenia and as a fluorescent probe in HPLC.
guanidine : An aminocarboxamidine, the parent compound of the guanidines.
Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The immunoperoxidase method, the autoclave method, and a newly developed alkaline-guanidine method were used to distinguish senile (SSA) and familial types (FAP) of prealbumin-related amyloidosis in formalin-fixed, paraffin-embedded tissue sections." | 3.67 | Novel histochemical approaches to the prealbumin-related senile and familial forms of systemic amyloidosis. ( Kitamoto, T; Tashima, T; Tateishi, J, 1986) |
| "The four lenses from the renal failure patients were searched for evidence of carbamylation at lysyl or cysteinyl residues: carbamylation was not detected." | 1.29 | Glutathione adducts, not carbamylated lysines, are the major modification of lens alpha-crystallins from renal failure patients. ( Miesbauer, LR; Schwedler, J; Shun-Shin, GA; Smith, DL; Smith, JB; Sun, Y; Yang, Z; Zhou, X, 1995) |
| "Glutaraldehyde treatment of articular cartilage for 30 minutes decreased is wear rate." | 1.26 | Factors influencing articular cartilage wear in vitro. ( McGrath, PJ; Paul, IL; Radin, EL; Swann, DA, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (40.00) | 18.7374 |
| 1990's | 6 (40.00) | 18.2507 |
| 2000's | 3 (20.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| BERTOLINI, AM | 1 |
| QUARTO DI PALO, FM | 1 |
| MOMBELLI, L | 1 |
| Meehan, S | 1 |
| Berry, Y | 1 |
| Luisi, B | 1 |
| Dobson, CM | 1 |
| Carver, JA | 1 |
| MacPhee, CE | 1 |
| Kim, YJ | 1 |
| Yokozawa, T | 1 |
| Chung, HY | 1 |
| Paulsson, M | 1 |
| Inerot, S | 1 |
| Heinegård, D | 2 |
| Radin, EL | 1 |
| Swann, DA | 1 |
| Paul, IL | 1 |
| McGrath, PJ | 1 |
| Tziafas, D | 1 |
| Smith, JB | 1 |
| Shun-Shin, GA | 1 |
| Sun, Y | 1 |
| Miesbauer, LR | 1 |
| Yang, Z | 2 |
| Zhou, X | 1 |
| Schwedler, J | 1 |
| Smith, DL | 1 |
| Bergenhem, NC | 1 |
| Lee, SJ | 1 |
| Gafni, A | 2 |
| Caine, WR | 1 |
| Tamminga, S | 1 |
| Verstegen, MW | 1 |
| Sauer, WC | 1 |
| Schulze, H | 1 |
| Smith, RK | 1 |
| Zunino, L | 1 |
| Webbon, PM | 1 |
| Katoh-Semba, R | 1 |
| Semba, R | 1 |
| Kato, K | 1 |
| Morishima-Kawashima, M | 1 |
| Oshima, N | 1 |
| Ogata, H | 1 |
| Yamaguchi, H | 1 |
| Yoshimura, M | 1 |
| Sugihara, S | 1 |
| Ihara, Y | 1 |
| Pinto, MR | 1 |
| Gorski, JP | 1 |
| Penniston, JT | 1 |
| Kelly, PJ | 1 |
| Zúñiga, A | 1 |
| Kitamoto, T | 1 |
| Tashima, T | 1 |
| Tateishi, J | 1 |
15 other studies available for guanidine and Aging
| Article | Year |
|---|---|
[The metabolism of guanidine compounds in senescent individuals. I. Variations in normal subjects due to age and sex].
Topics: Aging; Amidines; Guanidine; Guanidines; Sex | 1962 |
Amyloid fibril formation by lens crystallin proteins and its implications for cataract formation.
Topics: Aging; alpha-Crystallins; Amyloid; Animals; Benzothiazoles; beta-Crystallins; Cataract; Cattle; Dose | 2004 |
Effects of energy restriction and fish oil supplementation on renal guanidino levels and antioxidant defences in aged lupus-prone B/W mice.
Topics: Acetic Acid; Aging; Animals; Antioxidants; Arginine; Catalase; Creatinine; Dietary Supplements; Ener | 2005 |
Variation in quantity and extractability of the 148-kilodalton cartilage protein with age.
Topics: Aging; Animals; Cattle; Chromatography, Gel; Collagen; Electrophoresis, Polyacrylamide Gel; Extracel | 1984 |
Factors influencing articular cartilage wear in vitro.
Topics: Aging; Animals; Bone and Bones; Cartilage, Articular; Cattle; Female; Glutaral; Guanidine; Guanidine | 1982 |
Induction of reparative dentinogenesis in vivo: a synthesis of experimental observations.
Topics: Aging; Animals; Cell Differentiation; Connective Tissue; Connective Tissue Cells; Dental Pulp; Denta | 1995 |
Glutathione adducts, not carbamylated lysines, are the major modification of lens alpha-crystallins from renal failure patients.
Topics: Aged; Aged, 80 and over; Aging; Carbamates; Crystallins; Female; Glutathione; Guanidine; Guanidines; | 1995 |
The stable, inactive but reactivatable, unfolding intermediate of rat muscle sarcoplasmic reticulum Ca(2+)-ATPase differs from the age-modified form of this protein.
Topics: Aging; Animals; Calcium-Transporting ATPases; Enzyme Activation; Guanidine; Guanidines; Muscle, Skel | 1997 |
Endogenous recoveries and true ileal digestibilities of amino acids in newly weaned pigs fed diets with protease-treated soybean meal.
Topics: Administration, Topical; Aging; Amino Acids; Animals; Caseins; Chromium Compounds; Diet; Dietary Pro | 1997 |
The distribution of cartilage oligomeric matrix protein (COMP) in tendon and its variation with tendon site, age and load.
Topics: Aging; Animals; Blotting, Northern; Blotting, Western; Cartilage; Cattle; Electrophoresis, Polyacryl | 1997 |
An enhanced conversion from tightly bound to loosely bound form of NGF in selected regions of brains from male mice.
Topics: Aging; Animals; Brain; Female; Guanidine; Hippocampus; Male; Mice; Mice, Inbred Strains; Nerve Growt | 1998 |
Effect of apolipoprotein E allele epsilon4 on the initial phase of amyloid beta-protein accumulation in the human brain.
Topics: Adult; Aged; Aged, 80 and over; Aging; Alleles; Alzheimer Disease; Amyloid beta-Peptides; Apolipopro | 2000 |
Age-related changes in composition and Ca2+-binding capacity of canine cortical bone extracts.
Topics: Aging; Animals; Binding Sites; Bone and Bones; Calcium; Chondroitinases and Chondroitin Lyases; Dogs | 1988 |
Age-related modifications in rat cardiac phosphoglycerate kinase. Rejuvenation of the old enzyme by unfolding-refolding.
Topics: Aging; Animals; Guanidine; Guanidines; Heart; Kinetics; Myocardium; Phosphoglycerate Kinase; Protein | 1988 |
Novel histochemical approaches to the prealbumin-related senile and familial forms of systemic amyloidosis.
Topics: Aged; Aging; Alkalies; Amyloidosis; Guanidine; Guanidines; Histocytochemistry; Humans; Immunochemist | 1986 |