guanidine has been researched along with ALS - Amyotrophic Lateral Sclerosis in 4 studies
Guanidine: A strong organic base existing primarily as guanidium ions at physiological pH. It is found in the urine as a normal product of protein metabolism. It is also used in laboratory research as a protein denaturant. (From Martindale, the Extra Pharmacopoeia, 30th ed and Merck Index, 12th ed) It is also used in the treatment of myasthenia and as a fluorescent probe in HPLC.
guanidine : An aminocarboxamidine, the parent compound of the guanidines.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 3 (75.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mulligan, VK | 1 |
| Kerman, A | 1 |
| Ho, S | 1 |
| Chakrabartty, A | 1 |
| Rumfeldt, JA | 2 |
| Lepock, JR | 2 |
| Meiering, EM | 2 |
| Stathopulos, PB | 1 |
| Chakrabarrty, A | 1 |
| Ono, S | 1 |
| Yamauchi, M | 1 |
4 other studies available for guanidine and ALS - Amyotrophic Lateral Sclerosis
| Article | Year |
|---|---|
Denaturational stress induces formation of zinc-deficient monomers of Cu,Zn superoxide dismutase: implications for pathogenesis in amyotrophic lateral sclerosis.
Topics: Amyotrophic Lateral Sclerosis; Copper; Dimerization; Guanidine; Humans; Kinetics; Models, Molecular; | 2008 |
Unfolding and folding kinetics of amyotrophic lateral sclerosis-associated mutant Cu,Zn superoxide dismutases.
Topics: Amyotrophic Lateral Sclerosis; Apoproteins; Copper; Enzyme Stability; Guanidine; Humans; Hydrogen-Io | 2009 |
Mechanism and thermodynamics of guanidinium chloride-induced denaturation of ALS-associated mutant Cu,Zn superoxide dismutases.
Topics: Amyotrophic Lateral Sclerosis; Dose-Response Relationship, Drug; Guanidine; Humans; Kinetics; Mutati | 2006 |
Amyotrophic lateral sclerosis: increased solubility of skin collagen.
Topics: Amyotrophic Lateral Sclerosis; Collagen; Cyanogen Bromide; Guanidine; Guanidines; Humans; Hydrochlor | 1992 |