guanfacine has been researched along with Morphine Dependence in 2 studies
Guanfacine: A centrally acting antihypertensive agent with specificity towards ADRENERGIC ALPHA-2 RECEPTORS.
Morphine Dependence: Strong dependence, both physiological and emotional, upon morphine.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Clonidine was about 12 times more potent than guanfacine in inhibiting this autonomic symptom of withdrawal." | 1.27 | A comparison of the inhibitory effects of clonidine and guanfacine on the behavioral and autonomic components of morphine withdrawal in rats. ( Buccafusco, JJ; Marshall, DC; Turner, RM, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zigun, JR | 1 |
| Bannon, MJ | 1 |
| Roth, RH | 1 |
| Buccafusco, JJ | 1 |
| Marshall, DC | 1 |
| Turner, RM | 1 |
2 other studies available for guanfacine and Morphine Dependence
| Article | Year |
|---|---|
Comparison of two alpha-noradrenergic agonists (clonidine and guanfacine) on norepinephrine turnover in the cortex of rats during morphine abstinence.
Topics: Adrenergic alpha-Agonists; Animals; Cerebral Cortex; Clonidine; Dose-Response Relationship, Drug; Gu | 1981 |
A comparison of the inhibitory effects of clonidine and guanfacine on the behavioral and autonomic components of morphine withdrawal in rats.
Topics: Adrenergic alpha-Agonists; Animals; Autonomic Nervous System; Behavior, Animal; Blood Pressure; Clon | 1984 |