guanfacine has been researched along with Kidney Failure, Chronic in 4 studies
Guanfacine: A centrally acting antihypertensive agent with specificity towards ADRENERGIC ALPHA-2 RECEPTORS.
Kidney Failure, Chronic: The end-stage of CHRONIC RENAL INSUFFICIENCY. It is characterized by the severe irreversible kidney damage (as measured by the level of PROTEINURIA) and the reduction in GLOMERULAR FILTRATION RATE to less than 15 ml per min (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002). These patients generally require HEMODIALYSIS or KIDNEY TRANSPLANTATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The principal pharmacokinetic parameters of guanfacine were greatly altered, with extended biotransformation and a decrease in the half-life compared to the values observed in other cases of severe renal insufficiency." | 1.27 | Pharmacokinetic aspects of guanfacine withdrawal syndrome in a hypertensive patient with chronic renal failure. ( Comoy, E; Fillastre, JP; Godin, M; Guerret, M; Kiechel, JR; Lavene, D, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kiechel, JR | 2 |
| Lavene, D | 2 |
| Guerret, M | 1 |
| Comoy, E | 1 |
| Godin, M | 2 |
| Fillastre, JP | 2 |
| Lifshits, NL | 1 |
| Ermolenko, VM | 1 |
| Rozhdestvenskaia, TM | 1 |
| Tatsievskiĭ, VA | 1 |
| Panasiuk, VV | 1 |
| Kirch, W | 1 |
| Köhler, H | 1 |
| Braun, W | 1 |
| Gurret, M | 1 |
| Coustenoble, J | 1 |
| Petrover, M | 1 |
4 other studies available for guanfacine and Kidney Failure, Chronic
| Article | Year |
|---|---|
Pharmacokinetic aspects of guanfacine withdrawal syndrome in a hypertensive patient with chronic renal failure.
Topics: Female; Guanfacine; Guanidines; Humans; Hypertension; Kidney Failure, Chronic; Kinetics; Middle Aged | 1983 |
[Labetalol and guanfacine in the treatment of arterial hypertension in patients with chronic renal failure].
Topics: Adolescent; Adult; Antihypertensive Agents; Drug Therapy, Combination; Ethanolamines; Female; Guanfa | 1984 |
Elimination of guanfacine in patients with normal and impaired renal function.
Topics: Absorption; Adult; Antihypertensive Agents; Glomerular Filtration Rate; Guanfacine; Guanidines; Huma | 1980 |
[Pharmacokinetic study of guanfacine in patients with renal insufficiency and in patients under chronic dialysis (author's transl)].
Topics: Antihypertensive Agents; Female; Guanfacine; Guanidines; Humans; Kidney Failure, Chronic; Kinetics; | 1980 |