guanfacine has been researched along with Hypotension in 6 studies
Guanfacine: A centrally acting antihypertensive agent with specificity towards ADRENERGIC ALPHA-2 RECEPTORS.
Hypotension: Abnormally low BLOOD PRESSURE that can result in inadequate blood flow to the brain and other vital organs. Common symptom is DIZZINESS but greater negative impacts on the body occur when there is prolonged depravation of oxygen and nutrients.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We describe a 4-year-old boy who presents to the emergency department with lethargy, bradycardia, and initial hypertension followed by hypotension due to guanfacine toxicity after ingestion of standard doses of the extended release formulation." | 3.78 | Treatment of guanfacine toxicity with naloxone. ( Dayan, PS; Tsze, DS, 2012) |
| "MK-912 and idazoxan dose-dependently reversed both clonidine and guanfacine-induced cognitive improvement and hypotension." | 3.71 | Actions of alpha-2 noradrenergic agonists on spatial working memory and blood pressure in rhesus monkeys appear to be mediated by the same receptor subtype. ( Arnsten, AF; Franowicz, JS, 2002) |
| "Clonidine was associated with the most respiratory (799, 2." | 1.40 | Unintentional pediatric exposures to central alpha-2 agonists reported to the National Poison Data System. ( Heard, K; Le Lait, MC; Wang, GS, 2014) |
| " B-HT920 was found to produce a dose-response profile qualitatively similar to, but weaker than, clonidine: low doses impaired memory and began to lower blood pressure and produce sedation, while high doses improved memory." | 1.27 | The alpha-2 adrenergic agonist guanfacine improves memory in aged monkeys without sedative or hypotensive side effects: evidence for alpha-2 receptor subtypes. ( Arnsten, AF; Cai, JX; Goldman-Rakic, PS, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (33.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 3 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, GS | 1 |
| Le Lait, MC | 1 |
| Heard, K | 1 |
| Walton, J | 1 |
| Byrum, M | 1 |
| Shumaker, A | 1 |
| Coury, DL | 1 |
| Tsze, DS | 1 |
| Dayan, PS | 1 |
| Franowicz, JS | 1 |
| Arnsten, AF | 2 |
| Granier, P | 1 |
| Arsac, P | 1 |
| Debru, JL | 1 |
| Cai, JX | 1 |
| Goldman-Rakic, PS | 1 |
6 other studies available for guanfacine and Hypotension
| Article | Year |
|---|---|
Unintentional pediatric exposures to central alpha-2 agonists reported to the National Poison Data System.
Topics: Adrenergic alpha-2 Receptor Agonists; Bradycardia; Child; Child, Preschool; Clonidine; Female; Guanf | 2014 |
Prolonged bradycardia and hypotension following guanfacine extended release overdose.
Topics: Adrenergic alpha-2 Receptor Agonists; Attention Deficit Disorder with Hyperactivity; Bradycardia; Ch | 2014 |
Treatment of guanfacine toxicity with naloxone.
Topics: Antihypertensive Agents; Attention Deficit Disorder with Hyperactivity; Blood Pressure; Child, Presc | 2012 |
Actions of alpha-2 noradrenergic agonists on spatial working memory and blood pressure in rhesus monkeys appear to be mediated by the same receptor subtype.
Topics: Adrenergic Agents; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Blood Pressure; | 2002 |
[Guanfacine poisoning].
Topics: Adult; Female; Guanfacine; Guanidines; Humans; Hypotension; Isoproterenol; Phenylacetates | 1982 |
The alpha-2 adrenergic agonist guanfacine improves memory in aged monkeys without sedative or hypotensive side effects: evidence for alpha-2 receptor subtypes.
Topics: Adrenergic alpha-Agonists; Aging; Animals; Azepines; Dioxanes; Dose-Response Relationship, Drug; Fem | 1988 |