guanfacine has been researched along with Hypertension, Renal in 6 studies
Guanfacine: A centrally acting antihypertensive agent with specificity towards ADRENERGIC ALPHA-2 RECEPTORS.
Hypertension, Renal: Persistent high BLOOD PRESSURE due to KIDNEY DISEASES, such as those involving the renal parenchyma, the renal vasculature, or tumors that secrete RENIN.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Effects of guanfacine, a centrally acting antihypertensive, on blood pressure, heart rate, plasma renin activity, serum aldosterone, plasma norepinephrine, and renal function were evaluated in 16 patients with hypertension with biopsy-proved chronic glomerulonephritis." | 7.67 | Effects of guanfacine monotherapy on blood pressure, heart rate, plasma renin activity, aldosterone, and catecholamines in hypertensive patients with chronic glomerulonephritis. ( Gomi, T; Ikeda, T; Nakayama, D; Sakurai, J; Yuhara, M, 1988) |
| "Efficacy of guanfacine was studied in 20 hypertensive patients and 20 patients with diabetes mellitus and hypertension in a 12-month follow-up." | 5.06 | Long-term clinical experience with guanfacine. ( Brimichová, G; Dzúrik, R; Fetkovská, N; Sebeková, K, 1987) |
| "Guanfacine, a new centrally acting alpha-mimetic antihypertensive drug, was given to two groups of 7 patients each, one with essential and the other with renal hypertension." | 5.05 | [Haemodynamic investigations with the new antihypertensive drug guanfacine (author's transl)]. ( Raschig, A; Rauh, J; Rosenthal, J; Schäfer, N, 1980) |
| "Effects of guanfacine, a centrally acting antihypertensive, on blood pressure, heart rate, plasma renin activity, serum aldosterone, plasma norepinephrine, and renal function were evaluated in 16 patients with hypertension with biopsy-proved chronic glomerulonephritis." | 3.67 | Effects of guanfacine monotherapy on blood pressure, heart rate, plasma renin activity, aldosterone, and catecholamines in hypertensive patients with chronic glomerulonephritis. ( Gomi, T; Ikeda, T; Nakayama, D; Sakurai, J; Yuhara, M, 1988) |
| "The centrally acting alphamimetic antihypertensive drug, guanfacine, was studied in normotensive volunteers and patients with essential and renal hypertension." | 3.67 | Hemodynamic and endocrine responses to guanfacine in normotensive volunteers and hypertensive patients. ( Rosenthal, JH, 1986) |
| " The vasodepressor effect of guanfacine was clearly dose-dependent, and was more marked when the initial level of the blood pressure was high, while that of clonidine was dose-dependent, only within a limited dosage range." | 1.26 | [Antihypertensive effect of guanfacine in rats]. ( Hamamura, M; Hashimoto, T; Imai, S; Kumada, M; Mitomi, A; Nakagawa, Y; Sakurai, H; Takeda, K, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nakagawa, Y | 1 |
| Takeda, K | 1 |
| Hashimoto, T | 1 |
| Sakurai, H | 1 |
| Mitomi, A | 1 |
| Imai, S | 1 |
| Hamamura, M | 1 |
| Kumada, M | 1 |
| Roeckel, A | 1 |
| Heidland, A | 1 |
| Rosenthal, J | 1 |
| Schäfer, N | 1 |
| Rauh, J | 1 |
| Raschig, A | 1 |
| Ikeda, T | 1 |
| Gomi, T | 1 |
| Yuhara, M | 1 |
| Sakurai, J | 1 |
| Nakayama, D | 1 |
| Fetkovská, N | 1 |
| Brimichová, G | 1 |
| Sebeková, K | 1 |
| Dzúrik, R | 1 |
| Rosenthal, JH | 1 |
2 trials available for guanfacine and Hypertension, Renal
| Article | Year |
|---|---|
[Haemodynamic investigations with the new antihypertensive drug guanfacine (author's transl)].
Topics: Adult; Antihypertensive Agents; Cardiac Output; Drug Evaluation; Female; Guanfacine; Guanidines; Hea | 1980 |
Long-term clinical experience with guanfacine.
Topics: Antihypertensive Agents; Blood Pressure; Clinical Trials as Topic; Diabetic Angiopathies; Follow-Up | 1987 |
4 other studies available for guanfacine and Hypertension, Renal
| Article | Year |
|---|---|
[Antihypertensive effect of guanfacine in rats].
Topics: Anesthesia; Animals; Antihypertensive Agents; Blood Pressure; Clonidine; Consciousness; Decerebrate | 1981 |
Acute and chronic renal effects of guanfacine in essential and renal hypertension.
Topics: Antihypertensive Agents; Blood Pressure; Creatinine; Drug Therapy, Combination; Electrolytes; Glomer | 1980 |
Effects of guanfacine monotherapy on blood pressure, heart rate, plasma renin activity, aldosterone, and catecholamines in hypertensive patients with chronic glomerulonephritis.
Topics: Adult; Aldosterone; Antihypertensive Agents; Blood Pressure; Catecholamines; Chronic Disease; Drug A | 1988 |
Hemodynamic and endocrine responses to guanfacine in normotensive volunteers and hypertensive patients.
Topics: Administration, Oral; Adult; Blood Pressure; Cardiac Output; Drug Evaluation; Female; Guanfacine; Gu | 1986 |