guanfacine has been researched along with Disease Models, Animal in 12 studies
Guanfacine: A centrally acting antihypertensive agent with specificity towards ADRENERGIC ALPHA-2 RECEPTORS.
Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Yohimbine had no effect on form-deprivation myopia, but 200 nmol reduced the myopia-inhibiting effect of goggle removal." | 3.91 | Alpha ( Carr, BJ; Nguyen, CT; Stell, WK, 2019) |
| "Guanfacine, which is an alpha-2 agonist with a higher affinity for the 2A, compared with 2B or 2C, subtypes, also blocked the ability of PCP to increase dopamine efflux in the prefrontal cortex." | 1.35 | Clonidine and guanfacine attenuate phencyclidine-induced dopamine overflow in rat prefrontal cortex: mediating influence of the alpha-2A adrenoceptor subtype. ( Elsworth, JD; Jentsch, JD; Roth, RH; Sanchez, D, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (16.67) | 29.6817 |
| 2010's | 7 (58.33) | 24.3611 |
| 2020's | 3 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Solinski, HJ | 1 |
| Dranchak, P | 1 |
| Oliphant, E | 1 |
| Gu, X | 1 |
| Earnest, TW | 1 |
| Braisted, J | 1 |
| Inglese, J | 1 |
| Hoon, MA | 1 |
| Abrams, RPM | 1 |
| Yasgar, A | 1 |
| Teramoto, T | 1 |
| Lee, MH | 1 |
| Dorjsuren, D | 1 |
| Eastman, RT | 1 |
| Malik, N | 1 |
| Zakharov, AV | 1 |
| Li, W | 1 |
| Bachani, M | 1 |
| Brimacombe, K | 1 |
| Steiner, JP | 1 |
| Hall, MD | 1 |
| Balasubramanian, A | 1 |
| Jadhav, A | 1 |
| Padmanabhan, R | 1 |
| Simeonov, A | 1 |
| Nath, A | 1 |
| Ji, Y | 1 |
| Shi, W | 1 |
| Yang, J | 1 |
| Ma, B | 1 |
| Jin, T | 1 |
| Cao, B | 1 |
| Liu, X | 1 |
| Ma, K | 1 |
| Jogamoto, T | 1 |
| Utsunomiya, R | 1 |
| Sato, A | 1 |
| Kihara, N | 1 |
| Choudhury, ME | 1 |
| Miyanishi, K | 1 |
| Kubo, M | 1 |
| Nagai, M | 1 |
| Nomoto, M | 1 |
| Yano, H | 1 |
| Shimizu, YI | 1 |
| Fukuda, M | 1 |
| Ishii, E | 1 |
| Eguchi, M | 1 |
| Tanaka, J | 1 |
| Carr, BJ | 1 |
| Nguyen, CT | 1 |
| Stell, WK | 1 |
| Kawaura, K | 1 |
| Karasawa, J | 1 |
| Chaki, S | 1 |
| Hikichi, H | 1 |
| Pillidge, K | 1 |
| Porter, AJ | 1 |
| Dudley, JA | 1 |
| Tsai, YC | 1 |
| Heal, DJ | 1 |
| Stanford, SC | 1 |
| Fredriksson, I | 1 |
| Jayaram-Lindström, N | 1 |
| Wirf, M | 1 |
| Nylander, E | 1 |
| Nyström, E | 1 |
| Jardemark, K | 1 |
| Steensland, P | 1 |
| Freeman, ZT | 1 |
| Rice, KA | 1 |
| Soto, PL | 1 |
| Pate, KA | 1 |
| Weed, MR | 1 |
| Ator, NA | 1 |
| DeLeon, IG | 1 |
| Wong, DF | 1 |
| Zhou, Y | 1 |
| Mankowski, JL | 1 |
| Zink, MC | 1 |
| Adams, RJ | 1 |
| Hutchinson, EK | 1 |
| Jentsch, JD | 2 |
| Sanchez, D | 1 |
| Elsworth, JD | 1 |
| Roth, RH | 1 |
| Uzsoki, B | 1 |
| Tóth, M | 1 |
| Hernádi, I | 1 |
12 other studies available for guanfacine and Disease Models, Animal
| Article | Year |
|---|---|
Inhibition of natriuretic peptide receptor 1 reduces itch in mice.
Topics: Animals; Behavior, Animal; Cell-Free System; Dermatitis, Contact; Disease Models, Animal; Ganglia, S | 2019 |
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Dr | 2020 |
Effect of sympathetic sprouting on the excitability of dorsal root ganglion neurons and afferents in a rat model of neuropathic pain.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic Fibers; An | 2022 |
Lister hooded rats as a novel animal model of attention-deficit/hyperactivity disorder.
Topics: Animals; Atomoxetine Hydrochloride; Attention; Attention Deficit Disorder with Hyperactivity; Diseas | 2020 |
Alpha
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Animals; Axial Length | 2019 |
Stimulation of postsynapse adrenergic α2A receptor improves attention/cognition performance in an animal model of attention deficit hyperactivity disorder.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Animals; Attention; Attention Defic | 2014 |
The behavioural response of mice lacking NK₁ receptors to guanfacine resembles its clinical profile in treatment of ADHD.
Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Anxiety; Attention; Attention Deficit Disorder with H | 2014 |
Evaluation of guanfacine as a potential medication for alcohol use disorder in long-term drinking rats: behavioral and electrophysiological findings.
Topics: Alcohol Deterrents; Alcohol Drinking; Alcohol-Related Disorders; Animals; Central Nervous System Dep | 2015 |
Neurocognitive dysfunction and pharmacological intervention using guanfacine in a rhesus macaque model of self-injurious behavior.
Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Attention; Behavior, Animal; Carbon Radioisotopes; Co | 2015 |
Clonidine and guanfacine attenuate phencyclidine-induced dopamine overflow in rat prefrontal cortex: mediating influence of the alpha-2A adrenoceptor subtype.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agon | 2008 |
Novelty response of rats determines the effect of prefrontal alpha-2 adrenoceptor modulation on anxiety.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Animals; Anxiety; Dis | 2011 |
Impaired visuospatial divided attention in the spontaneously hypertensive rat.
Topics: Adrenergic alpha-Agonists; Analysis of Variance; Animals; Attention; Attention Deficit and Disruptiv | 2005 |