guanfacine has been researched along with Chronic Motor and Vocal Tic Disorder in 12 studies
Guanfacine: A centrally acting antihypertensive agent with specificity towards ADRENERGIC ALPHA-2 RECEPTORS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A 16-year-old female with Tourette's syndrome presented with diaphoresis, dry mouth, and hypertension 8 h after ingesting 25 mg of guanfacine." | 7.76 | Guanfacine overdose resulting in initial hypertension and subsequent delayed, persistent orthostatic hypotension. ( Clark, RF; Minns, AB; Schneir, A, 2010) |
| "A 16-year-old female with Tourette's syndrome presented with diaphoresis, dry mouth, and hypertension 8 h after ingesting 25 mg of guanfacine." | 3.76 | Guanfacine overdose resulting in initial hypertension and subsequent delayed, persistent orthostatic hypotension. ( Clark, RF; Minns, AB; Schneir, A, 2010) |
| "Risperidone and clonidine were the most commonly recommended medications for tic disorders over the study period, with 36,868 and 35,500 recommendations in 2016, respectively." | 1.51 | Prescriptions for Alpha Agonists and Antipsychotics in Children and Youth with Tic Disorders: A Pharmacoepidemiologic Study. ( Cothros, N; Martino, D; McMorris, C; Pringsheim, T; Stewart, D; Tehrani, A, 2019) |
| "Guanfacine hydrochloride is an alpha-2 adrenergic agonist, which has gained recent attention in the field of child and adolescent psychiatry." | 1.30 | Guanfacine and secondary mania in children. ( Barnhill, LJ; Horrigan, JP, 1999) |
| "Guanfacine is an alpha 2-adrenergic agonist that may have beneficial effects on attention, without the hypotensive or sedative effects of clonidine, which is often used as an alternative to stimulants." | 1.29 | Guanfacine treatment of comorbid attention-deficit hyperactivity disorder and Tourette's syndrome: preliminary clinical experience. ( Arnsten, A; Chappell, PB; Cohen, DJ; Leckman, JF; Lynch, KA; Riddle, MA; Scahill, L; Schultz, R, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (41.67) | 18.2507 |
| 2000's | 2 (16.67) | 29.6817 |
| 2010's | 4 (33.33) | 24.3611 |
| 2020's | 1 (8.33) | 2.80 |
| Authors | Studies |
|---|---|
| Roessner, V | 1 |
| Eichele, H | 1 |
| Stern, JS | 1 |
| Skov, L | 1 |
| Rizzo, R | 1 |
| Debes, NM | 1 |
| Nagy, P | 1 |
| Cavanna, AE | 1 |
| Termine, C | 1 |
| Ganos, C | 1 |
| Münchau, A | 1 |
| Szejko, N | 1 |
| Cath, D | 1 |
| Müller-Vahl, KR | 1 |
| Verdellen, C | 1 |
| Hartmann, A | 1 |
| Rothenberger, A | 1 |
| Hoekstra, PJ | 1 |
| Plessen, KJ | 1 |
| Cothros, N | 1 |
| Martino, D | 1 |
| McMorris, C | 1 |
| Stewart, D | 1 |
| Tehrani, A | 1 |
| Pringsheim, T | 2 |
| Kawabe, K | 1 |
| Horiuchi, F | 1 |
| Ueno, SI | 1 |
| Minns, AB | 1 |
| Clark, RF | 1 |
| Schneir, A | 1 |
| Doja, A | 1 |
| Gorman, D | 1 |
| McKinlay, D | 1 |
| Day, L | 1 |
| Billinghurst, L | 1 |
| Carroll, A | 1 |
| Dion, Y | 1 |
| Luscombe, S | 1 |
| Steeves, T | 1 |
| Sandor, P | 1 |
| Castellanos, FX | 1 |
| Acosta, MT | 1 |
| King, A | 1 |
| Harris, P | 1 |
| Fritzell, J | 1 |
| Kurlan, R | 1 |
| Chappell, PB | 1 |
| Riddle, MA | 2 |
| Scahill, L | 1 |
| Lynch, KA | 1 |
| Schultz, R | 1 |
| Arnsten, A | 1 |
| Leckman, JF | 1 |
| Cohen, DJ | 1 |
| Walkup, JT | 1 |
| Scahill, LD | 1 |
| Fras, I | 1 |
| Horrigan, JP | 2 |
| Barnhill, LJ | 2 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Finalizing and Testing an Online Therapist Training and Assistance Program to Facilitate Implementation of Comprehensive Behavioral Intervention for Tic Disorders[NCT05547854] | 234 participants (Anticipated) | Interventional | 2023-06-27 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 reviews available for guanfacine and Chronic Motor and Vocal Tic Disorder
| Article | Year |
|---|---|
European clinical guidelines for Tourette syndrome and other tic disorders-version 2.0. Part III: pharmacological treatment.
Topics: Adult; Attention Deficit Disorder with Hyperactivity; Child; Female; Guanfacine; Humans; Male; Rispe | 2022 |
Canadian guidelines for the evidence-based treatment of tic disorders: pharmacotherapy.
Topics: Adrenergic alpha-2 Receptor Agonists; Adult; Antipsychotic Agents; Canada; Child; Clonidine; Evidenc | 2012 |
Syncope in children with Tourette's syndrome treated with guanfacine.
Topics: Child; Electrocardiography; Guanfacine; Humans; Sympathomimetics; Syncope; Tourette Syndrome | 2006 |
Disruptive behavior, hyperactivity, and learning disabilities in children with Tourette's syndrome.
Topics: Adolescent; Antidepressive Agents, Tricyclic; Attention Deficit Disorder with Hyperactivity; Child; | 1995 |
8 other studies available for guanfacine and Chronic Motor and Vocal Tic Disorder
| Article | Year |
|---|---|
Prescriptions for Alpha Agonists and Antipsychotics in Children and Youth with Tic Disorders: A Pharmacoepidemiologic Study.
Topics: Adolescent; Antipsychotic Agents; Aripiprazole; Child; Child, Preschool; Female; Guanfacine; Humans; | 2019 |
Combination treatment with guanfacine extended release and blonanserin for Tourette's syndrome comorbid with attention deficit hyperactivity disorder.
Topics: Adrenergic alpha-2 Receptor Agonists; Attention Deficit Disorder with Hyperactivity; Child; Comorbid | 2019 |
Guanfacine overdose resulting in initial hypertension and subsequent delayed, persistent orthostatic hypotension.
Topics: Adolescent; Adrenergic alpha-Agonists; Blood Pressure; Drug Overdose; Electrocardiography; Female; G | 2010 |
[Tourette syndrome: an analysis of its comorbidity and specific treatment].
Topics: Adrenergic alpha-Agonists; Antipsychotic Agents; Atomoxetine Hydrochloride; Attention Deficit Disord | 2004 |
Guanfacine treatment of comorbid attention-deficit hyperactivity disorder and Tourette's syndrome: preliminary clinical experience.
Topics: Adolescent; Adrenergic Agonists; Attention Deficit Disorder with Hyperactivity; Child; Female; Follo | 1995 |
Guanfacine for Tourette's disorder.
Topics: Adrenergic alpha-Agonists; Child; Dose-Response Relationship, Drug; Drug Administration Schedule; Gu | 1996 |
Does guanfacine trigger mania in children?
Topics: Adolescent; Adrenergic alpha-Agonists; Attention Deficit Disorder with Hyperactivity; Bipolar Disord | 1998 |
Guanfacine and secondary mania in children.
Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Bipolar Disorder; Child; Female; Guanfaci | 1999 |