guanfacine has been researched along with Anesthesia in 3 studies
Guanfacine: A centrally acting antihypertensive agent with specificity towards ADRENERGIC ALPHA-2 RECEPTORS.
Anesthesia: A state characterized by loss of feeling or sensation. This depression of nerve function is usually the result of pharmacologic action and is induced to allow performance of surgery or other painful procedures.
| Excerpt | Relevance | Reference |
|---|---|---|
| " With guanfacine the maximal fall of blood pressure was comparable to that obtained with the 5-HT1A receptor ligands; however, in contrast to the latter, the dose-response curve was U-shaped, the highest dose eliciting a pressor effect with reversal of the vasodilatation." | 1.28 | 8-OH-DPAT, flesinoxan and guanfacine: systemic and regional haemodynamic effects of centrally acting antihypertensive agents in anaesthetized rabbits. ( Fozard, JR; Hof, RP, 1989) |
| " The vasodepressor effect of guanfacine was clearly dose-dependent, and was more marked when the initial level of the blood pressure was high, while that of clonidine was dose-dependent, only within a limited dosage range." | 1.26 | [Antihypertensive effect of guanfacine in rats]. ( Hamamura, M; Hashimoto, T; Imai, S; Kumada, M; Mitomi, A; Nakagawa, Y; Sakurai, H; Takeda, K, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (66.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shimizu, S | 1 |
| Kawada, T | 1 |
| Akiyama, T | 1 |
| Turner, MJ | 1 |
| Shishido, T | 1 |
| Kamiya, A | 1 |
| Shirai, M | 1 |
| Sugimachi, M | 1 |
| Nakagawa, Y | 1 |
| Takeda, K | 1 |
| Hashimoto, T | 1 |
| Sakurai, H | 1 |
| Mitomi, A | 1 |
| Imai, S | 1 |
| Hamamura, M | 1 |
| Kumada, M | 1 |
| Hof, RP | 1 |
| Fozard, JR | 1 |
3 other studies available for guanfacine and Anesthesia
| Article | Year |
|---|---|
Guanfacine enhances cardiac acetylcholine release with little effect on norepinephrine release in anesthetized rabbits.
Topics: Acetylcholine; Adrenergic alpha-2 Receptor Agonists; Anesthesia; Animals; Dose-Response Relationship | 2015 |
[Antihypertensive effect of guanfacine in rats].
Topics: Anesthesia; Animals; Antihypertensive Agents; Blood Pressure; Clonidine; Consciousness; Decerebrate | 1981 |
8-OH-DPAT, flesinoxan and guanfacine: systemic and regional haemodynamic effects of centrally acting antihypertensive agents in anaesthetized rabbits.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic beta-Antagonists; Anesthesia; Animals; Antihypert | 1989 |