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guanfacine and Anesthesia

guanfacine has been researched along with Anesthesia in 3 studies

Guanfacine: A centrally acting antihypertensive agent with specificity towards ADRENERGIC ALPHA-2 RECEPTORS.

Anesthesia: A state characterized by loss of feeling or sensation. This depression of nerve function is usually the result of pharmacologic action and is induced to allow performance of surgery or other painful procedures.

Research Excerpts

ExcerptRelevanceReference
" With guanfacine the maximal fall of blood pressure was comparable to that obtained with the 5-HT1A receptor ligands; however, in contrast to the latter, the dose-response curve was U-shaped, the highest dose eliciting a pressor effect with reversal of the vasodilatation."1.288-OH-DPAT, flesinoxan and guanfacine: systemic and regional haemodynamic effects of centrally acting antihypertensive agents in anaesthetized rabbits. ( Fozard, JR; Hof, RP, 1989)
" The vasodepressor effect of guanfacine was clearly dose-dependent, and was more marked when the initial level of the blood pressure was high, while that of clonidine was dose-dependent, only within a limited dosage range."1.26[Antihypertensive effect of guanfacine in rats]. ( Hamamura, M; Hashimoto, T; Imai, S; Kumada, M; Mitomi, A; Nakagawa, Y; Sakurai, H; Takeda, K, 1981)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19902 (66.67)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Shimizu, S1
Kawada, T1
Akiyama, T1
Turner, MJ1
Shishido, T1
Kamiya, A1
Shirai, M1
Sugimachi, M1
Nakagawa, Y1
Takeda, K1
Hashimoto, T1
Sakurai, H1
Mitomi, A1
Imai, S1
Hamamura, M1
Kumada, M1
Hof, RP1
Fozard, JR1

Other Studies

3 other studies available for guanfacine and Anesthesia

ArticleYear
Guanfacine enhances cardiac acetylcholine release with little effect on norepinephrine release in anesthetized rabbits.
    Autonomic neuroscience : basic & clinical, 2015, Volume: 187

    Topics: Acetylcholine; Adrenergic alpha-2 Receptor Agonists; Anesthesia; Animals; Dose-Response Relationship

2015
[Antihypertensive effect of guanfacine in rats].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1981, Volume: 77, Issue:3

    Topics: Anesthesia; Animals; Antihypertensive Agents; Blood Pressure; Clonidine; Consciousness; Decerebrate

1981
8-OH-DPAT, flesinoxan and guanfacine: systemic and regional haemodynamic effects of centrally acting antihypertensive agents in anaesthetized rabbits.
    British journal of pharmacology, 1989, Volume: 96, Issue:4

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic beta-Antagonists; Anesthesia; Animals; Antihypert

1989