guanfacine has been researched along with Alcoholism in 2 studies
Guanfacine: A centrally acting antihypertensive agent with specificity towards ADRENERGIC ALPHA-2 RECEPTORS.
Alcoholism: A primary, chronic disease with genetic, psychosocial, and environmental factors influencing its development and manifestations. The disease is often progressive and fatal. It is characterized by impaired control over drinking, preoccupation with the drug alcohol, use of alcohol despite adverse consequences, and distortions in thinking, most notably denial. Each of these symptoms may be continuous or periodic. (Morse & Flavin for the Joint Commission of the National Council on Alcoholism and Drug Dependence and the American Society of Addiction Medicine to Study the Definition and Criteria for the Diagnosis of Alcoholism: in JAMA 1992;268:1012-4)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Our key findings are that alcohol dependence induced by gavage produces sex-specific effects on reinstatement." | 1.72 | Role of alpha-2 adrenergic and kappa opioid receptors in the effects of alcohol gavage-induced dependence on alcohol seeking. ( Coen, K; Funk, D; Lê, AD; Mak, D, 2022) |
| "High rates of comorbidity between alcohol use disorder (AUD) and major depressive disorder (MDD) are reported." | 1.40 | A sustained depressive state promotes a guanfacine reversible susceptibility to alcohol seeking in rats. ( De Vries, TJ; Hoogendijk, WJ; Riga, D; Schmitz, LJ; Smit, AB; Spijker, S; van der Harst, JE; van Mourik, Y, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Funk, D | 1 |
| Mak, D | 1 |
| Coen, K | 1 |
| Lê, AD | 1 |
| Riga, D | 1 |
| Schmitz, LJ | 1 |
| van der Harst, JE | 1 |
| van Mourik, Y | 1 |
| Hoogendijk, WJ | 1 |
| Smit, AB | 1 |
| De Vries, TJ | 1 |
| Spijker, S | 1 |
2 other studies available for guanfacine and Alcoholism
| Article | Year |
|---|---|
Role of alpha-2 adrenergic and kappa opioid receptors in the effects of alcohol gavage-induced dependence on alcohol seeking.
Topics: Adrenergic Agents; Alcoholism; Animals; Ethanol; Female; Guanfacine; Male; Rats; Rats, Long-Evans; R | 2022 |
A sustained depressive state promotes a guanfacine reversible susceptibility to alcohol seeking in rats.
Topics: Adrenergic alpha-2 Receptor Agonists; Alcohol Drinking; Alcoholism; Animals; Central Nervous System | 2014 |