guanethidine has been researched along with Syncope in 5 studies
Guanethidine: An antihypertensive agent that acts by inhibiting selectively transmission in post-ganglionic adrenergic nerves. It is believed to act mainly by preventing the release of norepinephrine at nerve endings and causes depletion of norepinephrine in peripheral sympathetic nerve terminals as well as in tissues.
guanethidine : A member of the class of guanidines in which one of the hydrogens of the amino group has been replaced by a 2-azocan-1-ylethyl group.
guanethidine sulfate : A organic sulfate salt composed of two molecules of guanethidine and one of sulfuric acid.
Syncope: A transient loss of consciousness and postural tone caused by diminished blood flow to the brain (i.e., BRAIN ISCHEMIA). Presyncope refers to the sensation of lightheadedness and loss of strength that precedes a syncopal event or accompanies an incomplete syncope. (From Adams et al., Principles of Neurology, 6th ed, pp367-9)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Eighteen patients with essential hypertension uncontrolled by hydrochlorothiazide alone were randomly assigned to receive additional therapy with either guanadrel sulfate or guanethidine sulfate." | 5.05 | Comparison of guanadrel and guanethidine efficacy and side effects. ( Malinow, SH, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| STEWART, IM | 1 |
| Malinow, SH | 1 |
| Woo, R | 1 |
| McQueen, J | 1 |
| Ekbom, KA | 1 |
| Cuningham, JA | 1 |
1 trial available for guanethidine and Syncope
| Article | Year |
|---|---|
Comparison of guanadrel and guanethidine efficacy and side effects.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Diarrhea; Guanethidine; Guanidines; Humans; Hyperten | 1983 |
4 other studies available for guanethidine and Syncope
| Article | Year |
|---|---|
MECHANISMS OF SIMPLE FAINTING IN UNCOMPLICATED HYPERTENSION.
Topics: Blood Pressure Determination; Diagnosis; Drug Therapy; Guanethidine; Hypertension; Physiology; Synco | 1965 |
Apnea and syncope following intravenous guanethidine Bier block in the same patient on two different occasions.
Topics: Adult; Anesthesia, Conduction; Apnea; Autonomic Nerve Block; Female; Guanethidine; Humans; Syncope | 1987 |
Scotoma due to arterial hypotension.
Topics: Guanethidine; Humans; Hydrochlorothiazide; Hypertension; Hypotension; Male; Middle Aged; Scotoma; Sy | 1973 |
Hypertension and cerebrovascular disease, adverse effects of guanethidine.
Topics: Aged; Arteriosclerosis; Cerebrovascular Disorders; Female; Guanethidine; Humans; Hypertension; Hypot | 1967 |