guanethidine has been researched along with Scleroderma, Systemic in 2 studies
Guanethidine: An antihypertensive agent that acts by inhibiting selectively transmission in post-ganglionic adrenergic nerves. It is believed to act mainly by preventing the release of norepinephrine at nerve endings and causes depletion of norepinephrine in peripheral sympathetic nerve terminals as well as in tissues.
guanethidine : A member of the class of guanidines in which one of the hydrogens of the amino group has been replaced by a 2-azocan-1-ylethyl group.
guanethidine sulfate : A organic sulfate salt composed of two molecules of guanethidine and one of sulfuric acid.
Scleroderma, Systemic: A chronic multi-system disorder of CONNECTIVE TISSUE. It is characterized by SCLEROSIS in the SKIN, the LUNGS, the HEART, the GASTROINTESTINAL TRACT, the KIDNEYS, and the MUSCULOSKELETAL SYSTEM. Other important features include diseased small BLOOD VESSELS and AUTOANTIBODIES. The disorder is named for its most prominent feature (hard skin), and classified into subsets by the extent of skin thickening: LIMITED SCLERODERMA and DIFFUSE SCLERODERMA.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Blunt, RJ | 1 |
| Porter, JM | 1 |
| LeRoy, EC | 1 |
| Downey, JA | 1 |
| Cannon, PJ | 1 |
1 review available for guanethidine and Scleroderma, Systemic
| Article | Year |
|---|---|
Raynaud syndrome.
Topics: Adrenergic beta-Antagonists; Adult; Angiography; Antibodies, Antinuclear; Arterial Occlusive Disease | 1981 |
1 other study available for guanethidine and Scleroderma, Systemic
| Article | Year |
|---|---|
Skin capillary blood flow in scleroderma.
Topics: Adult; Body Temperature; Capillaries; Cold Temperature; Female; Guanethidine; Hot Temperature; Human | 1971 |