guanethidine has been researched along with Pregnancy in 50 studies
Guanethidine: An antihypertensive agent that acts by inhibiting selectively transmission in post-ganglionic adrenergic nerves. It is believed to act mainly by preventing the release of norepinephrine at nerve endings and causes depletion of norepinephrine in peripheral sympathetic nerve terminals as well as in tissues.
guanethidine : A member of the class of guanidines in which one of the hydrogens of the amino group has been replaced by a 2-azocan-1-ylethyl group.
guanethidine sulfate : A organic sulfate salt composed of two molecules of guanethidine and one of sulfuric acid.
Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We previously demonstrated that 7-d-old rat pups exposed to hypoxia from birth exhibit ACTH-independent increases in corticosterone associated with an increase in steroidogenic acute regulatory (StAR) and peripheral-type benzodiazepine receptor (PBR) proteins." | 7.72 | Basal and adrenocorticotropin-stimulated corticosterone in the neonatal rat exposed to hypoxia from birth: modulation by chemical sympathectomy. ( Engeland, WC; Lee, JJ; Oaks, MK; Raff, H; Widmaier, EP, 2004) |
| "We previously demonstrated that 7-d-old rat pups exposed to hypoxia from birth exhibit ACTH-independent increases in corticosterone associated with an increase in steroidogenic acute regulatory (StAR) and peripheral-type benzodiazepine receptor (PBR) proteins." | 3.72 | Basal and adrenocorticotropin-stimulated corticosterone in the neonatal rat exposed to hypoxia from birth: modulation by chemical sympathectomy. ( Engeland, WC; Lee, JJ; Oaks, MK; Raff, H; Widmaier, EP, 2004) |
| " Guanethidine, which like 6-OHDA, causes a prolonged sympathectomy did not interfere with the course of the pregnancy nor did bethanidine which interferes with sympathetic transmission without causing ultrastructural damage." | 3.66 | Studies on the mechanism of action of the abortive effect of 6-hydroxydopamine in rats. ( Airaksinen, MM; MacDonald, E, 1981) |
| "Guanethidine treatment attenuated the hypoxia-induced increase in cholesterol ester-bound arachidonic and adrenic acids." | 1.33 | Adrenal lipid profiles of chemically sympathectomized normoxic and hypoxic neonatal rats. ( Bruder, ED; Henderson, LM; Raff, H, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 47 (94.00) | 18.7374 |
| 1990's | 1 (2.00) | 18.2507 |
| 2000's | 2 (4.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| D'INCERTI BONINI, L | 1 |
| LAURICELLA, E | 1 |
| MAGGIORA-VERGANO, T | 1 |
| VILLAGRA, DR | 1 |
| ROSENVASSER, E | 1 |
| WIMHOEFER, H | 1 |
| JUNG, H | 1 |
| DAFTARY, SN | 1 |
| DESASOUZA, M | 1 |
| KUMAR, A | 1 |
| MANDREKAR, SS | 1 |
| LOTLIKAR, KD | 1 |
| SHETH, UK | 1 |
| WEST, GB | 1 |
| URSI, R | 1 |
| CORNELI, O | 1 |
| VERDINI, JE | 1 |
| URANGAIMAZ, FA | 3 |
| TONNELIER, E | 2 |
| KLAUER, D | 2 |
| CHEKHERDEMIAN, M | 1 |
| DEGROOT, LJ | 1 |
| CHEKERDEMIAN, M | 1 |
| DZOLJIC, M | 1 |
| SMITH, AJ | 2 |
| Raff, H | 2 |
| Lee, JJ | 1 |
| Widmaier, EP | 1 |
| Oaks, MK | 1 |
| Engeland, WC | 1 |
| Bruder, ED | 1 |
| Henderson, LM | 1 |
| Maughan, GB | 1 |
| Shabanah, EH | 1 |
| Toth, A | 1 |
| Cantor, EH | 1 |
| Greenberg, LH | 1 |
| Weiss, B | 1 |
| Wikland, M | 1 |
| Lindblom, B | 2 |
| Dahlström, A | 1 |
| Haglid, KG | 1 |
| Berkowitz, RL | 1 |
| MacDonald, E | 1 |
| Airaksinen, MM | 1 |
| Aloe, L | 1 |
| Levi-Montalcini, R | 1 |
| Johnson, EM | 2 |
| O'Brien, F | 1 |
| Werbitt, R | 1 |
| Culver, NG | 1 |
| Fischman, DA | 1 |
| Cantor, E | 1 |
| Douglas, JR | 1 |
| Shekhtman, MM | 1 |
| Volpin, EA | 1 |
| Turenko, AI | 1 |
| Zamanskaia, EM | 1 |
| Evans, BK | 1 |
| Burnstock, G | 1 |
| Bartolomé, J | 1 |
| Bartolomé, M | 1 |
| Seidler, J | 1 |
| Anderson, TR | 1 |
| Slotkin, TA | 1 |
| Finnerty, FA | 1 |
| Hodgson, BJ | 1 |
| Fremming, BD | 1 |
| Daly, S | 1 |
| Buchanan, GD | 1 |
| Garfield, RE | 1 |
| Jones, CT | 2 |
| Roebuck, MM | 2 |
| Walker, DW | 2 |
| Johnston, BM | 2 |
| Donnerer, J | 1 |
| Schuligoi, R | 1 |
| Lembeck, F | 1 |
| Bryman, I | 1 |
| Norström, A | 1 |
| Lagercrantz, H | 1 |
| Zander, J | 1 |
| Goebel, R | 1 |
| Kuhn, W | 1 |
| Abella, R | 1 |
| Blondeel, NJ | 1 |
| Roguska, J | 1 |
| Walker, C | 1 |
| Simon, NM | 1 |
| Del Greco, F | 1 |
| Kendle, KE | 1 |
| Bennett, JP | 1 |
| Breslin, DJ | 1 |
| Swinton, NW | 1 |
| Ryan, MJ | 1 |
| Clark, KE | 1 |
| Brody, MJ | 1 |
| Martin, JD | 1 |
| Haller, J | 1 |
| Restall, BJ | 1 |
| Hearnshaw, HR | 1 |
| Gleeson, AR | 1 |
| Thorburn, GD | 1 |
| Peretti, PO | 1 |
| Tucker, RM | 1 |
| Hunt, JC | 1 |
| Ratnam, SS | 1 |
| Lean, TH | 1 |
| Sivasamboo, R | 1 |
| Adler, NT | 1 |
| Heinrich, F | 1 |
| Schultis, K | 1 |
| Vorburger, C | 1 |
| Coppola, JA | 1 |
| Leonardi, RG | 1 |
| Lippmann, W | 1 |
| Perrine, JW | 1 |
| Ringler, I | 1 |
| Athanassiadis, D | 1 |
| Cranston, WI | 1 |
| Juel-Jensen, BE | 1 |
| Oliver, DO | 1 |
3 reviews available for guanethidine and Pregnancy
| Article | Year |
|---|---|
Anti-hypertensive drugs in the pregnant patient.
Topics: Antihypertensive Agents; Chronic Disease; Clonidine; Diazoxide; Diuretics; Female; Fetus; Furosemide | 1980 |
Elective surgery in hypertensive patients--preoperative considerations.
Topics: Diuretics; Female; Ganglionic Blockers; Guanethidine; Humans; Hypertension; Infant, Newborn; Methyld | 1970 |
Recent advances in the medical and surgical treatment of hypertension.
Topics: Adrenocortical Hyperfunction; Antihypertensive Agents; Diet, Sodium-Restricted; Diuretics; Ethacryni | 1968 |
1 trial available for guanethidine and Pregnancy
| Article | Year |
|---|---|
[Treatment of the hypertensive syndrome with hemiton and isobarin in certain diseases of pregnant women].
Topics: Blood Pressure; Clinical Trials as Topic; Clonidine; Drug Evaluation; Female; Guanethidine; Humans; | 1977 |
46 other studies available for guanethidine and Pregnancy
| Article | Year |
|---|---|
[Guanethidine: a new antihypertensive substance applied in obstetrics and gynecology].
Topics: Amidines; Antihypertensive Agents; Female; Guanethidine; Gynecology; Obstetrics; Pregnancy; Pregnanc | 1960 |
[The hypotensive action of a guanethidine derivative in hypertensive gestoses].
Topics: Amidines; Antihypertensive Agents; Female; Guanethidine; Hypertension; Hypotension; Pre-Eclampsia; P | 1960 |
[Our experience in the treatment of hypertensive gestosis with guanethidine and protoveratrine A. (Preliminary report)].
Topics: Female; Guanethidine; Hypertension; Pre-Eclampsia; Pregnancy; Protoveratrines; Toxemia; Veratrum; Ve | 1963 |
[Treatment of hypertension in eclampsia and pre-eclampsia with guanethidin "Ismelin"].
Topics: Amidines; Antihypertensive Agents; Eclampsia; Female; Guanethidine; Hypertension; Pre-Eclampsia; Pre | 1961 |
A CONTROLLED CLINICAL TRIAL OF GUANETHIDINE IN TOXEMIA OF PREGNANCY.
Topics: Blood Pressure; Blood Pressure Determination; Female; Guanethidine; Heart Rate; Humans; Infant; Infa | 1963 |
TERATOGENIC ACTIVITY OF DRUGS.
Topics: Abnormalities, Drug-Induced; Fetal Death; Guanethidine; Pregnancy; Rats; Research; Reserpine; Thalid | 1964 |
[TREATMENT OF HYPERTENSIVE GESTOSIS WITH GUANETHIDINE].
Topics: Female; Guanethidine; Humans; Hypertension; Pre-Eclampsia; Pregnancy | 1964 |
[DIURETIC DRUGS IN THE EDEMAS OF PREGNANCY].
Topics: Acetazolamide; Benzothiadiazines; Blood Pressure; Body Weight; Chlorothiazide; Diuretics; Edema; Fem | 1964 |
THERAPY OF THYROTOXICOSIS.
Topics: Adolescent; Antithyroid Agents; Child; Female; Goiter; Graves Disease; Guanethidine; Heart Diseases; | 1964 |
[THERAPEUTICS OF ARTERIAL HYPERTENSION IN PREGNANCY].
Topics: Female; Guanethidine; Hibernation; Humans; Hydralazine; Hypertension; Hypothermia, Induced; Maternal | 1964 |
ACTION OF GUANETHIDINE ON SMOOTH MUSCLE OF GUINEA PIG, RAT, RABBIT, AND LEECH DORSAL MUSCLE.
Topics: Acetylcholine; Animals; Barium; Bradykinin; Carbachol; Epinephrine; Female; Guanethidine; Guinea Pig | 1964 |
CLINICAL FEATURES OF FLUID RETENTION COMPLICATING TREATMENT WITH GUANETHIDINE.
Topics: Body Weight; Drug Therapy; Edema; Electrocardiography; Female; Geriatrics; Guanethidine; Hypertensio | 1965 |
Basal and adrenocorticotropin-stimulated corticosterone in the neonatal rat exposed to hypoxia from birth: modulation by chemical sympathectomy.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Aldosterone; Animals; Animals, Newborn; Body Weight; Ca | 2004 |
Adrenal lipid profiles of chemically sympathectomized normoxic and hypoxic neonatal rats.
Topics: Adrenal Glands; Animals; Animals, Newborn; Corticosterone; Female; Guanethidine; Hypoxia; Lipids; Pr | 2006 |
Experiments with pharmacologic sympatholysis in the gravid.
Topics: Adult; Animals; Dogs; Female; Guanethidine; Humans; Hydrochlorothiazide; Methyldopa; Obstetric Labor | 1967 |
Effect of long-term changes in sympathetic nervous activity on the beta-adrenergic receptor-adenylate cyclase complex of rat pineal gland.
Topics: Adenylyl Cyclases; Animals; Blindness; Female; Ganglia, Sympathetic; Guanethidine; Kinetics; Light; | 1981 |
Structural and functional evidence for the denervation of human myometrium during pregnancy.
Topics: Adult; Atropine; Autonomic Nervous System; Biopsy; Cesarean Section; Cytoplasm; Electric Stimulation | 1984 |
Studies on the mechanism of action of the abortive effect of 6-hydroxydopamine in rats.
Topics: Abortifacient Agents; Animals; Bethanidine; Catecholamines; Female; Fertility; Fetal Death; Fetal Re | 1981 |
Comparative studies on the effects elicited by pre- and postnatal injections of anti-NGF, guanethidine, and 6-hydroxydopamine in chromaffin and ganglion cells of the adrenal medulla and carotid body in infant rats.
Topics: Adrenal Medulla; Animals; Animals, Newborn; Antibodies; Carotid Body; Chromaffin System; Female; Fet | 1980 |
Modification and characterization of the permanent sympathectomy produced by the administration of guanethidine to newborn rats.
Topics: Adrenal Glands; Adrenal Medulla; Age Factors; Animals; Animals, Newborn; Blood Vessels; Brain Chemis | 1976 |
Pharmacological analysis of sympathetic function in the embryonic chick heart.
Topics: Animals; Autonomic Agents; Chick Embryo; Dimethylphenylpiperazinium Iodide; Dose-Response Relationsh | 1977 |
Biochemical and functional evaluation of the sympathectomy produced by the administration of guanethidine to newborn rats.
Topics: Adrenal Glands; Adrenalectomy; Animals; Animals, Newborn; Body Weight; Brain Chemistry; Epinephrine; | 1975 |
Management of hypertension.
Topics: Adrenergic beta-Antagonists; Age Factors; Bethanidine; Clonidine; Debrisoquin; Decision Making; Diur | 1975 |
Chronic guanethidine treatment of female rats including effects on the fetus.
Topics: Adrenergic Fibers; Animals; Electric Stimulation; Female; Guanethidine; In Vitro Techniques; Male; M | 1979 |
Effects of early postnatal guanethidine administration on adrenal medulla and brain of developing rats.
Topics: Adrenal Medulla; Aging; Animals; Animals, Newborn; Brain; Chlorisondamine; Female; Guanethidine; Org | 1976 |
Hypertension in pregnancy.
Topics: Abortion, Therapeutic; Adult; Blood Pressure; Diazoxide; Diuretics; Female; Furosemide; Guanethidine | 1975 |
Effects of adrenergic drugs administered during ovum transport and chemical sympathectomy of the oviduct on fertility in rabbits.
Topics: Animals; Ascorbic Acid; Atenolol; Autonomic Agents; Embryo Implantation; Fallopian Tubes; Female; Fe | 1975 |
Functional innervation of the myometrium of Myotis lucifugus, the little brown bat.
Topics: Animals; Atropine; Autonomic Agents; Carbachol; Cervix Uteri; Chiroptera; Electric Stimulation; Fema | 1990 |
Modulation of the responses of fetal sheep to adrenergic stimulation by adrenal demedullation and chemical sympathectomy.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Androgens; Animals; Blood Glucose; Blood Pressure; Epin | 1989 |
Influence of capsaicin-induced denervation on neurogenic and humoral control of arterial pressure.
Topics: Anesthesia; Animals; Blood Pressure; Capsaicin; Denervation; Female; Guanethidine; Neurons, Afferent | 1989 |
Response of isolated muscle of the human cervix to electrofield stimulation.
Topics: Cervix Uteri; Electric Stimulation; Female; Guanethidine; Humans; In Vitro Techniques; Muscle Contra | 1988 |
Cardiovascular, metabolic and endocrine effects of chemical sympathectomy and of adrenal demedullation in fetal sheep.
Topics: Adrenal Medulla; Animals; Cardiovascular Physiological Phenomena; Cardiovascular System; Catecholami | 1987 |
[Hypertension in pregnancy (author's transl)].
Topics: Alkaline Phosphatase; Estriol; Female; Fetal Diseases; Fetal Heart; Fetoscopy; Guanethidine; Humans; | 1974 |
Periodic dialysis in terminal uremia.
Topics: Adolescent; Adult; Anemia; Arthritis; Child; Female; Gastrointestinal Hemorrhage; Glaucoma; Glomerul | 1967 |
Studies upon the mechanism of reserpine-induced arrest in egg transport in the mouse oviduct. II. Comparative effects of some agents with actions on smooth muscle and tissue amines.
Topics: Amphetamine; Animals; Atropine; Catecholamines; Chlorpromazine; Ethanolamines; Female; Guanethidine; | 1969 |
Neurogenic and mechanical control of canine uterine vascular resistance.
Topics: Animals; Atropine; Cholinesterase Inhibitors; Constriction; Dilatation; Dimethylphenylpiperazinium I | 1974 |
The management of hypertensive disease of pregnancy.
Topics: Blood Pressure; Diazoxide; Eclampsia; Edema; Estrogens; Female; Guanethidine; Humans; Hypertension; | 1974 |
[Therapy of EPH gestosis].
Topics: Chlorthalidone; Diazepam; Diet Therapy; Eclampsia; Edema; Female; Furosemide; Guanethidine; Humans; | 1973 |
Observations on the luteolytic action of prostaglandin F 2 in the ewe.
Topics: Animals; Corpus Luteum; Estrus; Female; Guanethidine; Lidocaine; Pregnancy; Progesterone; Prostaglan | 1973 |
Effects of external genital sensory feedback on copulatory behavior of rats.
Topics: Anesthesia, Local; Animals; Copulation; Ejaculation; Estrus; Feedback; Female; Genitalia; Guanethidi | 1973 |
A comparison of hypotensive drugs in patients with hypertensive disorders in late pregnancy.
Topics: Antihypertensive Agents; Drug Synergism; Female; Guanethidine; Humans; Hypertension; Pre-Eclampsia; | 1971 |
Effects of the male's copulatory behavior on successful pregnancy of the female rat.
Topics: Animals; Copulation; Ejaculation; Estrus; Female; Fertilization; Guanethidine; Insemination; Insemin | 1969 |
[Therapy of hypertension].
Topics: Adrenal Gland Neoplasms; Aniline Compounds; Antihypertensive Agents; Diuretics; Female; Guanethidine | 1971 |
[The hypertensive crisis. Urgent therapeutic measures].
Topics: Antihypertensive Agents; Diazoxide; Drug Synergism; Female; Guanethidine; Humans; Hypertension; Male | 1967 |
Induction of pseudopregnancy in rats by depletors of endogenous catecholamines.
Topics: Aminocaproates; Amphetamine; Animals; Brain; Dihydroxyphenylalanine; Estrus; Female; Guanethidine; I | 1965 |
Clinical observations on the effects of debrisoquine sulphate in patients with high blood-pressure.
Topics: Adolescent; Adult; Aged; Amidines; Antihypertensive Agents; Female; Guanethidine; Humans; Hypertensi | 1966 |