guanethidine has been researched along with Peripheral Nerve Diseases in 8 studies
Guanethidine: An antihypertensive agent that acts by inhibiting selectively transmission in post-ganglionic adrenergic nerves. It is believed to act mainly by preventing the release of norepinephrine at nerve endings and causes depletion of norepinephrine in peripheral sympathetic nerve terminals as well as in tissues.
guanethidine : A member of the class of guanidines in which one of the hydrogens of the amino group has been replaced by a 2-azocan-1-ylethyl group.
guanethidine sulfate : A organic sulfate salt composed of two molecules of guanethidine and one of sulfuric acid.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The putative antinociceptive action of guanethidine and calcitonin systemically injected has been compared in 2 rat models of persistent experimental pain: Freund's adjuvant-induced arthritis (n = 29) and mononeuropathy induced by 4 loose ligatures around the sciatic nerve (n = 24)." | 3.68 | Are mechanical and cold allodynia in mononeuropathic and arthritic rats relieved by systemic treatment with calcitonin or guanethidine? ( Ardid, D; Attal, N; Guilbaud, G; Perrot, S, 1993) |
| "Treatment with guanethidine diminished heat and cold sensitization considerably, but had less effect on mechanical sensitization and, if administered before surgery, rather increased the severity of self-mutilating behaviour." | 1.28 | Effects of guanethidine on sensitization to natural stimuli and self-mutilating behaviour in rats with a peripheral neuropathy. ( Attal, N; Guilbaud, G; Neil, A, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (37.50) | 18.7374 |
| 1990's | 4 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (12.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kennedy, R | 1 |
| Hester, J | 1 |
| Simon, DW | 1 |
| Parry, CB | 1 |
| Kim, SH | 1 |
| Na, HS | 1 |
| Kwangsup, S | 1 |
| Jin, MC | 1 |
| Perrot, S | 1 |
| Attal, N | 2 |
| Ardid, D | 1 |
| Guilbaud, G | 2 |
| Breivik, H | 1 |
| Neil, A | 1 |
| Winkelmann, RK | 1 |
| Schroeter, AL | 1 |
| Kierland, RR | 1 |
| Ryan, TM | 1 |
| Abella, R | 1 |
| Blondeel, NJ | 1 |
| Roguska, J | 1 |
| Walker, C | 1 |
| Simon, NM | 1 |
| Del Greco, F | 1 |
8 other studies available for guanethidine and Peripheral Nerve Diseases
| Article | Year |
|---|---|
Malignancy as a possible complication of complex regional pain syndrome: a case report.
Topics: Adult; Amputation, Surgical; Arthralgia; Bone Neoplasms; Complex Regional Pain Syndromes; Drug Resis | 2010 |
Painful conditions of peripheral nerves.
Topics: Autonomic Nerve Block; Causalgia; Electric Stimulation; Female; Guanethidine; Humans; Median Nerve; | 1980 |
Effects of sympathectomy on a rat model of peripheral neuropathy.
Topics: Animals; Disease Models, Animal; Guanethidine; Hot Temperature; Male; Pain; Pain Measurement; Periph | 1993 |
Are mechanical and cold allodynia in mononeuropathic and arthritic rats relieved by systemic treatment with calcitonin or guanethidine?
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antidepressive Agents; Arthritis, Experimental; Be | 1993 |
Chronic pain and the sympathetic nervous system.
Topics: Autonomic Nervous System Diseases; Causalgia; Chronic Disease; Clinical Trials as Topic; Double-Blin | 1997 |
Effects of guanethidine on sensitization to natural stimuli and self-mutilating behaviour in rats with a peripheral neuropathy.
Topics: Animals; Cold Temperature; Guanethidine; Hot Temperature; Male; Peripheral Nervous System Diseases; | 1991 |
Clinical studies of livedoid vasculitis: (segmental hyalinizing vasculitis).
Topics: Adolescent; Adult; Aged; Blood Coagulation Tests; Blood Protein Electrophoresis; Child; Chronic Dise | 1974 |
Periodic dialysis in terminal uremia.
Topics: Adolescent; Adult; Anemia; Arthritis; Child; Female; Gastrointestinal Hemorrhage; Glaucoma; Glomerul | 1967 |