guanethidine has been researched along with Obesity in 10 studies
Guanethidine: An antihypertensive agent that acts by inhibiting selectively transmission in post-ganglionic adrenergic nerves. It is believed to act mainly by preventing the release of norepinephrine at nerve endings and causes depletion of norepinephrine in peripheral sympathetic nerve terminals as well as in tissues.
guanethidine : A member of the class of guanidines in which one of the hydrogens of the amino group has been replaced by a 2-azocan-1-ylethyl group.
guanethidine sulfate : A organic sulfate salt composed of two molecules of guanethidine and one of sulfuric acid.
Obesity: A status with BODY WEIGHT that is grossly above the recommended standards, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY).
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effect of neonatal sympathectomy with guanethidine (50 mg/kg for 3 wk) on the development of diet-induced obesity (DIO) was assessed by raising guanethidine-(G) or saline-treated (S) Sprague-Dawley rats in small litters (4-5 pups/dam) and feeding a high-calorie diet from weaning (n = 29-30) or by raising similarly treated rats in normal litters (10 pups/dam) and feeding chow from weaning (n = 29-30)." | 3.67 | Dietary obesity and neonatal sympathectomy. I. Effects on body composition and brown adipose. ( Levin, BE; Marquet, E; Sullivan, AC; Triscari, J, 1984) |
| "Current therapeutic strategies for the treatment of obesity are unsatisfactory." | 1.37 | Colon electrical stimulation: potential use for treatment of obesity. ( Chen, JD; Sallam, HS, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (80.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sánchez, A | 1 |
| Contreras, C | 1 |
| Martínez, P | 1 |
| Muñoz, M | 1 |
| Martínez, AC | 1 |
| García-Sacristán, A | 1 |
| Hernández, M | 1 |
| Prieto, D | 1 |
| Sallam, HS | 1 |
| Chen, JD | 1 |
| TURNER, RW | 1 |
| MILLIGAN, J | 1 |
| Levin, BE | 1 |
| Triscari, J | 1 |
| Marquet, E | 1 |
| Sullivan, AC | 1 |
| Powley, TL | 1 |
| Walgren, MC | 1 |
| Laughton, WB | 1 |
| Hickler, RB | 1 |
| Waal-Manning, HJ | 1 |
| Simpson, FO | 1 |
| Negoita, CJ | 1 |
| Cranston, WI | 1 |
| Moyer, JH | 1 |
1 review available for guanethidine and Obesity
| Article | Year |
|---|---|
Advances in medicine.
Topics: Acute Kidney Injury; Asthma; Blindness; Catecholamines; Contraceptives, Oral; Coronary Disease; Guan | 1968 |
1 trial available for guanethidine and Obesity
| Article | Year |
|---|---|
Fenfluramine in obese patients on various antihypertensive drugs. Double-blind controlled trial.
Topics: Antihypertensive Agents; Appetite Depressants; Blood Glucose; Blood Pressure; Body Weight; Cholester | 1969 |
8 other studies available for guanethidine and Obesity
| Article | Year |
|---|---|
Endothelin A (ET(A)) receptors are involved in augmented adrenergic vasoconstriction and blunted nitric oxide-mediated relaxation of penile arteries from insulin-resistant obese zucker rats.
Topics: Adrenergic Agents; Animals; Arteries; Endothelin A Receptor Antagonists; Endothelin-1; Erectile Dysf | 2014 |
Colon electrical stimulation: potential use for treatment of obesity.
Topics: Adrenergic Antagonists; Animals; Appetite Regulation; Autonomic Nervous System; Cecum; Colon; Dogs; | 2011 |
HYPERTENSION AND ITS COMPLICATIONS. 2.
Topics: Amobarbital; Antihypertensive Agents; Blood Pressure; Blood Pressure Determination; Cold Temperature | 1964 |
Dietary obesity and neonatal sympathectomy. I. Effects on body composition and brown adipose.
Topics: Adipose Tissue; Adipose Tissue, Brown; Animals; Animals, Newborn; Blood Glucose; Body Composition; B | 1984 |
Effects of guanethidine sympathectomy on ventromedial hypothalamic obesity.
Topics: Animals; Body Composition; Body Weight; Fatty Acids, Nonesterified; Ganglia, Sympathetic; Guanethidi | 1983 |
The office management of hypertension.
Topics: Adult; Age Factors; Ambulatory Care; Antihypertensive Agents; Benzothiadiazines; Black or African Am | 1975 |
[Present status in pathogenesis, diagnosis and therapy of arterial hypertension].
Topics: Arteriosclerosis; Guanethidine; Hemodynamics; Humans; Hypertension; Obesity; Reserpine | 1972 |
Optimum therapy for essential hypertension.
Topics: Antihypertensive Agents; Arteriosclerosis; Autonomic Nervous System; Blood Pressure; Chlorothiazide; | 1972 |