guanethidine has been researched along with Neuralgia in 16 studies
Guanethidine: An antihypertensive agent that acts by inhibiting selectively transmission in post-ganglionic adrenergic nerves. It is believed to act mainly by preventing the release of norepinephrine at nerve endings and causes depletion of norepinephrine in peripheral sympathetic nerve terminals as well as in tissues.
guanethidine : A member of the class of guanidines in which one of the hydrogens of the amino group has been replaced by a 2-azocan-1-ylethyl group.
guanethidine sulfate : A organic sulfate salt composed of two molecules of guanethidine and one of sulfuric acid.
Neuralgia: Intense or aching pain that occurs along the course or distribution of a peripheral or cranial nerve.
| Excerpt | Relevance | Reference |
|---|---|---|
| ") guanethidine blockade (RGB) was done over a 10 years period in patients with post-traumatic neuralgia." | 9.08 | Effects of regional intravenous guanethidine in patients with neuralgia in the hand; a follow-up study over a decade. ( Gordh, T; Torebjörk, E; Wahren, LK, 1995) |
| "A 25-year-old female developed causalgia following a nerve injury in the left hand, and this was treated successfully with a series of intravenous guanethidine blocks." | 7.67 | A case of prolonged hypotension following intravenous guanethidine block. ( Carli, F; Milaszkiewicz, R; Sharpe, E, 1987) |
| "Two cases of the causalgia syndrome have been presented, one probably related to a mild peripheral neuropathy and the second, more classically, following trauma." | 5.26 | The causalgia syndrome treated with regional intravenous guanethidine. ( Holland, JT, 1978) |
| ") guanethidine blockade (RGB) was done over a 10 years period in patients with post-traumatic neuralgia." | 5.08 | Effects of regional intravenous guanethidine in patients with neuralgia in the hand; a follow-up study over a decade. ( Gordh, T; Torebjörk, E; Wahren, LK, 1995) |
| " Sympathectomy using guanethidine significantly alleviated mechanical allodynia 6 weeks after cuff, when peak sympathetic sprouting was observed, having no effect at 2 weeks, when fibres were absent." | 3.81 | Sympathetic fibre sprouting in the skin contributes to pain-related behaviour in spared nerve injury and cuff models of neuropathic pain. ( Magnussen, C; Nascimento, FP; Ribeiro-da-Silva, A; Yousefpour, N, 2015) |
| "Intravenous regional sympathetic block with guanethidine caused only limited improvement in a patient with longstanding causalgia." | 3.67 | An unusual case of causalgia. Relevance to recent hypothesis on mechanism of causalgia. ( Charter, P; Hopkins, CS, 1989) |
| "A 25-year-old female developed causalgia following a nerve injury in the left hand, and this was treated successfully with a series of intravenous guanethidine blocks." | 3.67 | A case of prolonged hypotension following intravenous guanethidine block. ( Carli, F; Milaszkiewicz, R; Sharpe, E, 1987) |
| "Clinical and experimental studies of neuropathic pain support the hypothesis that a functional coupling between postganglionic sympathetic efferent and sensory afferent fibers contributes to the pain." | 1.34 | Delayed sympathetic dependence in the spared nerve injury (SNI) model of neuropathic pain. ( Allchorne, AJ; Beggah, AT; Decosterd, I; Pertin, M; Woolf, CJ, 2007) |
| "Two cases of the causalgia syndrome have been presented, one probably related to a mild peripheral neuropathy and the second, more classically, following trauma." | 1.26 | The causalgia syndrome treated with regional intravenous guanethidine. ( Holland, JT, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (75.00) | 18.7374 |
| 1990's | 2 (12.50) | 18.2507 |
| 2000's | 1 (6.25) | 29.6817 |
| 2010's | 1 (6.25) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nascimento, FP | 1 |
| Magnussen, C | 1 |
| Yousefpour, N | 1 |
| Ribeiro-da-Silva, A | 1 |
| Pertin, M | 1 |
| Allchorne, AJ | 1 |
| Beggah, AT | 1 |
| Woolf, CJ | 1 |
| Decosterd, I | 1 |
| Withrington, RH | 1 |
| Wynn Parry, CB | 1 |
| Tabira, T | 1 |
| Shibasaki, H | 1 |
| Kuroiwa, Y | 1 |
| Hannington-Kiff, JG | 2 |
| Nørregaard, TV | 1 |
| Schurizek, BA | 1 |
| Husegaard, HC | 1 |
| Wahren, LK | 2 |
| Gordh, T | 1 |
| Torebjörk, E | 2 |
| Holland, JT | 1 |
| Nyström, B | 1 |
| Hopkins, CS | 1 |
| Charter, P | 1 |
| McLelland, J | 1 |
| Ellis, SJ | 1 |
| Hodges, DL | 1 |
| McGuire, TJ | 1 |
| Davies, JA | 1 |
| Beswick, T | 1 |
| Dickson, G | 1 |
| Sharpe, E | 1 |
| Milaszkiewicz, R | 1 |
| Carli, F | 1 |
1 trial available for guanethidine and Neuralgia
| Article | Year |
|---|---|
Effects of regional intravenous guanethidine in patients with neuralgia in the hand; a follow-up study over a decade.
Topics: Adult; Aged; Arm; Autonomic Nerve Block; Female; Follow-Up Studies; Guanethidine; Hot Temperature; H | 1995 |
15 other studies available for guanethidine and Neuralgia
| Article | Year |
|---|---|
Sympathetic fibre sprouting in the skin contributes to pain-related behaviour in spared nerve injury and cuff models of neuropathic pain.
Topics: Adrenergic Fibers; Animals; Behavior, Animal; Calcitonin Gene-Related Peptide; Cold Temperature; Der | 2015 |
Delayed sympathetic dependence in the spared nerve injury (SNI) model of neuropathic pain.
Topics: Animals; Animals, Newborn; Disease Models, Animal; Ganglia, Spinal; Guanethidine; Immunohistochemist | 2007 |
The management of painful peripheral nerve disorders.
Topics: Causalgia; Denervation; Electric Stimulation; Guanethidine; Humans; Nerve Block; Neuralgia; Neurons, | 1984 |
Reflex sympathetic dystrophy (causalgia) treatment with guanethidine.
Topics: Aged; Causalgia; Female; Guanethidine; Humans; Male; Middle Aged; Neuralgia; Spinal Diseases | 1983 |
Hyperadrenergic-effected limb causalgia: relief by IV pharmacologic norepinephrine blockade.
Topics: Autonomic Nerve Block; Causalgia; Extremities; Guanethidine; Humans; Neuralgia; Norepinephrine | 1982 |
[Intravenous block with guanethidine in the treatment of of hyperpathic painful conditions of the extremities].
Topics: Adult; Aged; Causalgia; Extremities; Female; Guanethidine; Humans; Injections, Intravenous; Male; Mi | 1982 |
The retracted ephapse.
Topics: Arm; Autonomic Nerve Block; Causalgia; Guanethidine; Humans; Leg; Nerve Fibers; Neuralgia; Neurons, | 1978 |
Relief of causalgia in limbs yb regional intravenous guanethidine.
Topics: Adult; Aged; Anesthesia, Conduction; Anesthesia, Intravenous; Causalgia; Extremities; Guanethidine; | 1979 |
The causalgia syndrome treated with regional intravenous guanethidine.
Topics: Adolescent; Causalgia; Female; Guanethidine; Humans; Injections, Intravenous; Middle Aged; Neuralgia | 1978 |
Quantitative sensory testing before and after regional guanethidine block in patients with neuralgia in the hand.
Topics: Adult; Autonomic Nerve Block; Female; Guanethidine; Hand; Humans; Male; Middle Aged; Neuralgia; Pall | 1991 |
An unusual case of causalgia. Relevance to recent hypothesis on mechanism of causalgia.
Topics: Autonomic Nerve Block; Causalgia; Guanethidine; Humans; Male; Middle Aged; Neuralgia | 1989 |
Causalgia as a complication of meningococcal meningitis.
Topics: Adult; Causalgia; Guanethidine; Humans; Male; Meningitis, Meningococcal; Neuralgia | 1986 |
Burning and pain after injury. Is it causalgia or reflex sympathetic dystrophy?
Topics: Adrenal Cortex Hormones; Autonomic Nerve Block; Causalgia; Diagnosis, Differential; Exercise Therapy | 1988 |
Ketanserin and guanethidine in the treatment of causalgia.
Topics: Administration, Oral; Causalgia; Female; Guanethidine; Humans; Injections, Intravenous; Ketanserin; | 1987 |
A case of prolonged hypotension following intravenous guanethidine block.
Topics: Adult; Anesthesia, Intravenous; Autonomic Nerve Block; Causalgia; Female; Guanethidine; Hand; Humans | 1987 |