Page last updated: 2024-10-28

guanethidine and Leishmaniasis, Visceral

guanethidine has been researched along with Leishmaniasis, Visceral in 1 studies

Guanethidine: An antihypertensive agent that acts by inhibiting selectively transmission in post-ganglionic adrenergic nerves. It is believed to act mainly by preventing the release of norepinephrine at nerve endings and causes depletion of norepinephrine in peripheral sympathetic nerve terminals as well as in tissues.
guanethidine : A member of the class of guanidines in which one of the hydrogens of the amino group has been replaced by a 2-azocan-1-ylethyl group.
guanethidine sulfate : A organic sulfate salt composed of two molecules of guanethidine and one of sulfuric acid.

Leishmaniasis, Visceral: A chronic disease caused by LEISHMANIA DONOVANI and transmitted by the bite of several sandflies of the genera Phlebotomus and Lutzomyia. It is commonly characterized by fever, chills, vomiting, anemia, hepatosplenomegaly, leukopenia, hypergammaglobulinemia, emaciation, and an earth-gray color of the skin. The disease is classified into three main types according to geographic distribution: Indian, Mediterranean (or infantile), and African.

Research Excerpts

ExcerptRelevanceReference
" At the maximum dosage after 24 h of permanent contact with the cells (extreme, non-physiological conditions), cytolysis did not exceed 30%."1.30Action of new organometallic complexes against Leishmania donovani. ( Craciunescu, D; Lazuen, J; Mesa-Valle, CM; Moraleda, V; Osuna, A, 1997)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Mesa-Valle, CM1
Moraleda, V1
Lazuen, J1
Craciunescu, D1
Osuna, A1

Other Studies

1 other study available for guanethidine and Leishmaniasis, Visceral

ArticleYear
Action of new organometallic complexes against Leishmania donovani.
    The Journal of antimicrobial chemotherapy, 1997, Volume: 40, Issue:1

    Topics: Animals; Chromatin; Cricetinae; DNA, Protozoan; Drug Evaluation, Preclinical; Guanethidine; Leishman

1997