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guanethidine and Intraocular Pressure

guanethidine has been researched along with Intraocular Pressure in 81 studies

Guanethidine: An antihypertensive agent that acts by inhibiting selectively transmission in post-ganglionic adrenergic nerves. It is believed to act mainly by preventing the release of norepinephrine at nerve endings and causes depletion of norepinephrine in peripheral sympathetic nerve terminals as well as in tissues.
guanethidine : A member of the class of guanidines in which one of the hydrogens of the amino group has been replaced by a 2-azocan-1-ylethyl group.
guanethidine sulfate : A organic sulfate salt composed of two molecules of guanethidine and one of sulfuric acid.

Intraocular Pressure: The pressure of the fluids in the eye.

Research Excerpts

ExcerptRelevanceReference
"Patients with glaucoma received either 3% guanethidine-0."9.05Timolol v guanethidine-epinephrine formulations in the treatment of glaucoma. An open clinical trial. ( Hoyng, PF; Verbey, NL, 1984)
"Undesirable side effects have limited the use of adrenaline/guanethidine combinations in the usual concentrations in the treatment of chronic simple glaucoma."9.05Treatment of chronic simple glaucoma with an adrenaline/guanethidine combination at three different dosages (comparative double-blind study). ( Aeschlimann, JE; Gloor, BP; Urner-Bloch, U, 1980)
"In a double-blind cross-over study, the intraocular pressure-lowering action and side effects of a 5% guanethidine/1% adrenaline combination were studied and compared with those of two components alone."9.04A double-blind clinical trial of a guanethidine/adrenaline combination, compared with the two separate components, in glaucoma. ( Aeschlimann, J; Eltz, H; Gloor, B, 1978)
" This study showed that an association of adrenaline and guanethidine in drop form, used in cases of open-angle glaucoma, achieved a rapid and lasting stabilisation of intraocular pressure."9.04Therapeutic trial of the combination in an eye lotion of adrenaline (0.5 or 1%) and guanethidine (3 or 5%) in cases of open-angle glaucoma. ( Bardy, M, 1979)
"Thirty patients with ocular hypertension or open-angle glaucoma were tested to see if, and to what extent, guanethidine/dipivefrin and pilocarpine produced a supplementary reduction in intraocular pressure."7.67[Guanethidine/dipivefrin and pilocarpine in the treatment of increased intraocular pressure]. ( Dausch, D; Ober, M; Scharrer, A, 1987)
"Over a period of 4 months, 16 of 24 patients (30 of 46 eyes) with either primary open angle glaucoma (POAG) or suspected glaucoma were treated successfully with a maintenance dose of guanethidine (3%) and adrenaline (0."7.66Maintenance therapy of glaucoma patients with guanethidine (3%) and adrenaline (0.5%) once daily. ( Dake, CL; Hoyng, PF, 1980)
"In the study reported here, the relation between the dilatation of the pupil and the course of intraocular pressure (IOP) is examined in open angle glaucoma patients and in glaucoma suspects after topical administration of the combination of guanethidine 3% and adrenaline 0."7.66Guanethidine - adrenaline eye drops in glaucoma simplex. Pupil behaviour and response of intraocular pressure. ( Dake, CL; Hoyng, PF, 1981)
"Thirty-one patients (58 eyes) with either primary open angle glaucoma (19 patients with 34 eyes) or suspected glaucoma (12 patients with 24 eyes) were treated for a period of 7 months with only guanethidine 1% and epinephrine 0."7.66The combination of guanethidine 1% and epinephrine 0.2% in one eye drop (GA-weak) in the treatment of glaucoma. ( Dake, CL; Hoyng, PF, 1980)
"During a 7-month period 33 patients (20 with primary open-angle glaucoma and 13 with suspected glaucoma) were treated with guanethidine 3% and adrenaline 0."7.66The combination of guanethidine 3% and adrenaline 0.5% in 1 eyedrop (GA) in glaucoma treatment. ( Dake, CL; Hoyng, FJ, 1979)
" Six rabbits were used and the efficiencies of 5 different dosage protocols was estimated both as intensity and duration of activity."5.25Effect of adrenaline and guanethidine in reducing intraocular pressure in rabbits' eyes. ( Davies, DJ; Harvey, J; Jones, DE; Norton, DA, 1975)
"The effect on the intraocular pressure of patients with primary open-angle glaucoma of a combination of timolol 0."5.06[Treatment of glaucoma chronicum simplex with a combination of 0.5 percent timolol with 0.5 percent adrenaline plus 0.3 percent guanethidine]. ( Grehn, F; Pfeiffer, N, 1989)
"5% timolol or saline uniocularly with saline to the other eye, and the intraocular pressure was measured by applanation tonometry at 0, 30, 60, 120, and 240 minutes."5.06Sympathetic influences on the consensual ophthalmotonic reaction. ( Gibbens, MV, 1988)
"Patients with glaucoma received either 3% guanethidine-0."5.05Timolol v guanethidine-epinephrine formulations in the treatment of glaucoma. An open clinical trial. ( Hoyng, PF; Verbey, NL, 1984)
"Undesirable side effects have limited the use of adrenaline/guanethidine combinations in the usual concentrations in the treatment of chronic simple glaucoma."5.05Treatment of chronic simple glaucoma with an adrenaline/guanethidine combination at three different dosages (comparative double-blind study). ( Aeschlimann, JE; Gloor, BP; Urner-Bloch, U, 1980)
"In a double-blind cross-over study, the intraocular pressure-lowering action and side effects of a 5% guanethidine/1% adrenaline combination were studied and compared with those of two components alone."5.04A double-blind clinical trial of a guanethidine/adrenaline combination, compared with the two separate components, in glaucoma. ( Aeschlimann, J; Eltz, H; Gloor, B, 1978)
" This study showed that an association of adrenaline and guanethidine in drop form, used in cases of open-angle glaucoma, achieved a rapid and lasting stabilisation of intraocular pressure."5.04Therapeutic trial of the combination in an eye lotion of adrenaline (0.5 or 1%) and guanethidine (3 or 5%) in cases of open-angle glaucoma. ( Bardy, M, 1979)
"Assessment was made of 5% local guanethidine in treating eye manifestations in euthyroid patients with either treated thyrotoxicosis or ophthalmic Graves's disease."5.03Critical study of 5 per cent guanethidine in ocular manifestations of Graves's disease. ( Anderson, J; Cartlidge, NE; Crombie, AL; Hall, R, 1969)
"Thirty patients with ocular hypertension or open-angle glaucoma were tested to see if, and to what extent, guanethidine/dipivefrin and pilocarpine produced a supplementary reduction in intraocular pressure."3.67[Guanethidine/dipivefrin and pilocarpine in the treatment of increased intraocular pressure]. ( Dausch, D; Ober, M; Scharrer, A, 1987)
"Over a period of 4 months, 16 of 24 patients (30 of 46 eyes) with either primary open angle glaucoma (POAG) or suspected glaucoma were treated successfully with a maintenance dose of guanethidine (3%) and adrenaline (0."3.66Maintenance therapy of glaucoma patients with guanethidine (3%) and adrenaline (0.5%) once daily. ( Dake, CL; Hoyng, PF, 1980)
"Thirty-one patients (58 eyes) with either primary open angle glaucoma (19 patients with 34 eyes) or suspected glaucoma (12 patients with 24 eyes) were treated for a period of 7 months with only guanethidine 1% and epinephrine 0."3.66The combination of guanethidine 1% and epinephrine 0.2% in one eye drop (GA-weak) in the treatment of glaucoma. ( Dake, CL; Hoyng, PF, 1980)
"1% noradrenaline or 10% phenylepherine to either a surgically sympathectomised or a guanethidine treated rabbit eye induced a transient increase in intraocular pressure (IOP), between 90 and 150 min, followed by a fall to hypotensive levels."3.66Prostaglandin mediated inflammatory changes induced by alpha-adrenoceptor stimulation in the sympathectomised rabbit eye. ( Unger, WG, 1979)
"During a 7-month period 33 patients (20 with primary open-angle glaucoma and 13 with suspected glaucoma) were treated with guanethidine 3% and adrenaline 0."3.66The combination of guanethidine 3% and adrenaline 0.5% in 1 eyedrop (GA) in glaucoma treatment. ( Dake, CL; Hoyng, FJ, 1979)

Research

Studies (81)

TimeframeStudies, this research(%)All Research%
pre-199081 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
BONOMI, L6
DI COMITE, P3
STEPANIK, J1
UENO, K1
TUJI, K1
FUKUDA, H1
DIOTALLEVI, M1
TIBERI, GF1
PANNARALE, C1
PRIMROSE, J1
RAGNETTI, E1
OOSTERHUIS, JA1
D'Ermo, F1
DiComite, P1
Crombie, AL3
Lawson, AA1
O'Connor, MA1
Mooney, DJ1
Hoyng, PF7
Verbey, NL1
Heilmann, K1
Mills, KB1
Hercules, B1
English, M1
Urner-Bloch, U1
Aeschlimann, JE1
Gloor, BP1
Dake, CL7
Murray, A1
Glover, D2
Hitchings, R1
Hitchings, RA1
van Husen, H1
Demailly, P2
Duperre, J1
Unger, WG1
Hoyng, FJ2
Greve, EL1
Jones, DE2
Norton, DA2
Davies, DJ2
Romano, J2
Eltz, H1
Aeschlimann, J1
Gloor, B1
Patterson, G1
Bardy, M1
Krieglstein, GK1
Arden, GB1
Jacobson, JJ1
Tieri, O2
Rossini, L1
Merté, HJ3
Tomazzoli, L1
Jaria, D1
Nagasubramanian, S1
Tripathi, RC1
Poinoosawmy, D1
Gloster, J2
Macri, FJ2
Cevario, SJ2
Harvey, J1
Pfeiffer, N2
Grehn, F2
Gibbens, MV1
Smith, RJ1
Ober, M2
Scharrer, A2
Dausch, D1
Holland, MG1
Psilas, K1
Houber, JP1
Paterson, GD1
Paterson, G1
Zetterlund, O1
Lamble, JW1
Kulshrestha, OP1
Sharma, PC1
Kageyama, M1
Endo, Y1
Yamada, E1
Collignon, J1
Prijot, E1
Cartlidge, NE1
Anderson, J1
Hall, R1
Asregadoo, ER1
Hovland, KR1
Galloway, NR1
Birmingham, AT1
Aviner, Z1
Toppel, L1
Filho Carvalho, HP1
Awasthi, P1
Raizada, VN1
Srivastava, MP1
Trzcińska-Dabrowska, Z1
Majewska, K1
Takase, M1
Burberi, P1
Piccinelli, D1
Silvestrini, B1
Gonçalves, JO1
Niemeyer, G1
Csigány, A1
Bron, AJ1
Sousa Ramalho, P1
Reich D'Almeida, F1
Coelho da Fonseca, D1
Hendley, ED1
Eakins, KE1
Iuglio, N1

Reviews

4 reviews available for guanethidine and Intraocular Pressure

ArticleYear
[A review of glaucoma 1974-1975].
    Archives d'ophtalmologie, 1976, Volume: 36, Issue:3

    Topics: Acetazolamide; Chronic Disease; Diagnosis, Differential; Female; Glaucoma; Guanethidine; Humans; Hyd

1976
Autonomic drugs in ophthalmology: Some problems and promises. Section IV: Sympatholytic and sympathetic blocking agents--alpha adrenergic antagonists and beta adrenergic antagonists.
    Annals of ophthalmology, 1974, Volume: 6, Issue:11

    Topics: Adrenergic Agents; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Dibenzocycloheptenes;

1974
[Glaucoma].
    Archives d'ophtalmologie et revue generale d'ophtalmologie, 1968, Volume: 28, Issue:2

    Topics: Acetazolamide; Angiography; Aqueous Humor; Cataract; Cholinesterase Inhibitors; Chronic Disease; Dex

1968
Effects of drugs on aqueous humor dynamics.
    International ophthalmology clinics, 1971, Volume: 11, Issue:2

    Topics: Adrenal Cortex Hormones; Anesthetics; Animals; Carbonic Anhydrase Inhibitors; Cats; Chymotrypsin; Co

1971

Trials

20 trials available for guanethidine and Intraocular Pressure

ArticleYear
The additional pressure-lowering effect in patients with glaucoma of pilocarpine 2 per cent, adrenaline 1 per cent, or guanethidine 3 per cent with adrenaline 0.5 per cent and timolol 0.25 per cent: a double-blind cross-over study.
    Transactions of the ophthalmological societies of the United Kingdom, 1983, Volume: 103 ( Pt 6)

    Topics: Aged; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Epinephrine; Female;

1983
Timolol v guanethidine-epinephrine formulations in the treatment of glaucoma. An open clinical trial.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1984, Volume: 102, Issue:12

    Topics: Adult; Aged; Aqueous Humor; Circadian Rhythm; Clinical Trials as Topic; Drug Combinations; Epinephri

1984
Two blind randomized cross-over trials in the treatment of primary open angle glaucoma.
    Transactions of the ophthalmological societies of the United Kingdom, 1981, Volume: 101 (Pt 4)

    Topics: Aged; Clinical Trials as Topic; Drug Combinations; Drug Therapy, Combination; Epinephrine; Female; G

1981
Treatment of chronic simple glaucoma with an adrenaline/guanethidine combination at three different dosages (comparative double-blind study).
    Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie. Albrecht von Graefe's archive for clinical and experimental ophthalmology, 1980, Volume: 213, Issue:3

    Topics: Double-Blind Method; Drug Therapy, Combination; Epinephrine; Glaucoma; Guanethidine; Humans; Intraoc

1980
Low-dose combined guanethedine 1% and adrenaline 0.5% in the treatment of chronic simple glaucoma: a prospective study.
    The British journal of ophthalmology, 1981, Volume: 65, Issue:8

    Topics: Aged; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Epinephrine; Female;

1981
Adrenaline 1% combined with guanethidine 1% versus adrenaline 1%: a randomised prospective double-blind cross-over study.
    The British journal of ophthalmology, 1982, Volume: 66, Issue:4

    Topics: Clinical Trials as Topic; Double-Blind Method; Drug Combinations; Drug Synergism; Epinephrine; Glauc

1982
A double-blind short-term trial of guanethidine 3% and adrenaline 0.5% combined in one eye drop.
    Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie. Albrecht von Graefe's archive for clinical and experimental ophthalmology, 1977, Jul-08, Volume: 203, Issue:1

    Topics: Clinical Trials as Topic; Drug Combinations; Epinephrine; False Negative Reactions; Glaucoma; Guanet

1977
Low dosage combined adrenaline-guanethidine formulations in the management of chronic simple glaucoma.
    Transactions of the ophthalmological societies of the United Kingdom, 1977, Volume: 97, Issue:1

    Topics: Adult; Aged; Animals; Chronic Disease; Clinical Trials as Topic; Conjunctiva; Drug Therapy, Combinat

1977
Use of guanethidine 5% and adrenaline 1% in the treatment of severe open angle glaucoma.
    Transactions of the ophthalmological societies of the United Kingdom, 1977, Volume: 97, Issue:1

    Topics: Clinical Trials as Topic; Depression, Chemical; Drug Therapy, Combination; Epinephrine; Glaucoma; Gu

1977
A double-blind clinical trial of a guanethidine/adrenaline combination, compared with the two separate components, in glaucoma.
    Acta ophthalmologica, 1978, Volume: 56, Issue:2

    Topics: Clinical Trials as Topic; Conjunctivitis; Double-Blind Method; Drug Combinations; Drug Evaluation; E

1978
Evaluation of a 5% guanethidine and 0.5% adrenaline mixture (Ganda 5.05) and of a 3% guanethidine and 0.5% adrenaline mixture (Ganda 3.05) in the treatment of open-angle glaucoma.
    The British journal of ophthalmology, 1979, Volume: 63, Issue:1

    Topics: Clinical Trials as Topic; Drug Combinations; Drug Evaluation; Epinephrine; Glaucoma; Guanethidine; H

1979
Therapeutic trial of the combination in an eye lotion of adrenaline (0.5 or 1%) and guanethidine (3 or 5%) in cases of open-angle glaucoma.
    Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde, 1979, Volume: 178, Issue:1-2

    Topics: Clinical Trials as Topic; Drug Combinations; Drug Evaluation; Epinephrine; Female; Glaucoma; Guaneth

1979
[Treatment of glaucoma chronicum simplex with a combination of 0.5 percent timolol with 0.5 percent adrenaline plus 0.3 percent guanethidine].
    Klinische Monatsblatter fur Augenheilkunde, 1989, Volume: 194, Issue:3

    Topics: Clinical Trials as Topic; Drug Therapy, Combination; Epinephrine; Glaucoma, Open-Angle; Guanethidine

1989
Sympathetic influences on the consensual ophthalmotonic reaction.
    The British journal of ophthalmology, 1988, Volume: 72, Issue:10

    Topics: Aged; Female; Guanethidine; Horner Syndrome; Humans; Intraocular Pressure; Male; Middle Aged; Neuron

1988
The Lang lecture 1986. The enigma of primary open-angle glaucoma.
    Transactions of the ophthalmological societies of the United Kingdom, 1986, Volume: 105 ( Pt 6)

    Topics: Adult; Aged; Clinical Trials as Topic; Epinephrine; Female; Follow-Up Studies; Glaucoma, Open-Angle;

1986
Drug therapy of glaucoma.
    The British journal of ophthalmology, 1972, Volume: 56, Issue:3

    Topics: Aged; Amino Acids; Bronchodilator Agents; Circadian Rhythm; Clinical Trials as Topic; Epinephrine; F

1972
Critical study of 5 per cent guanethidine in ocular manifestations of Graves's disease.
    British medical journal, 1969, Dec-13, Volume: 4, Issue:5684

    Topics: Clinical Trials as Topic; Eye Manifestations; Eyelid Diseases; Female; Graves Disease; Guanethidine;

1969
Guanethidine ophthalmic solution 5 per cent. Use in the treatment of endocrine exophthalmos.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1970, Volume: 84, Issue:1

    Topics: Adult; Blepharoptosis; Blood Pressure; Clinical Trials as Topic; Conjunctiva; Dilatation; Exophthalm

1970
Guanethidine in chronic simple glaucoma.
    Annals of ophthalmology, 1971, Volume: 3, Issue:8

    Topics: Chronic Disease; Clinical Trials as Topic; Drug Synergism; Drug Therapy, Combination; Glaucoma; Guan

1971
Ismelin 1 percent drops in glaucoma.
    The Indian practitioner, 1965, Volume: 18, Issue:9

    Topics: Clinical Trials as Topic; Glaucoma; Guanethidine; Humans; Intraocular Pressure

1965

Other Studies

57 other studies available for guanethidine and Intraocular Pressure

ArticleYear
[Action of guanethidine on intraocular pressure].
    Annali di ottalmologia e clinica oculistica, 1963, Volume: 89

    Topics: Eye Diseases; Glaucoma; Guanethidine; Intraocular Pressure; Tetrahymenina; Tonometry, Ocular

1963
[The intraocular pressure-decreasing effect of a 10/0 aqueous solution of guanethidine (Ismelin, Ciba) instilled into the conjunctival sac in glaucoma simplex].
    Wiener klinische Wochenschrift, 1963, May-17, Volume: 75

    Topics: Glaucoma; Glaucoma, Open-Angle; Guanethidine; Intraocular Pressure

1963
[Trial use of a drug to reduce intraocular pressure, 10 per cent Ismelin, as eye drops].
    Rinsho ganka. Japanese journal of clinical ophthalmology, 1963, Volume: 17

    Topics: Eye Diseases; Glaucoma; Guanethidine; Humans; Intraocular Pressure; Ophthalmic Solutions; Tetrahymen

1963
[EFFECTS OF GUANETHIDINE ON OCULAR FLUID DYNAMICS].
    Annali di ottalmologia e clinica oculistica, 1963, Volume: 89

    Topics: Eye; Eye Diseases; Glaucoma; Guanethidine; Humans; Hydrodynamics; Intraocular Pressure; Tonometry, O

1963
[ON THE EFFECTS OF THE ASSOCIATION OF PILOCARPINE AND GUANETHIDINE INTRAOCULAR TENSION].
    Bollettino d'oculistica, 1963, Volume: 42

    Topics: Eye Diseases; Glaucoma; Guanethidine; Humans; Hydrophthalmos; Intraocular Pressure; Pharmacology; Pi

1963
MECHANISM OF PRODUCTION OF PAPILLOEDEMA.
    The British journal of ophthalmology, 1964, Volume: 48

    Topics: Astrocytoma; Drug Therapy; Glaucoma; Guanethidine; Humans; Hypertension; Hypertension, Malignant; In

1964
[ON ACTION OF INSTILLATION OF GUANETHIDINE ON EXPERIMENTAL OCULAR HYPERTENSION IN THE RABBIT].
    Bollettino d'oculistica, 1964, Volume: 43

    Topics: Animals; Eye Diseases; Guanethidine; Intraocular Pressure; Lagomorpha; Ocular Hypertension; Pharmaco

1964
Guanethidine (Ismelin) in ophthalmology. I. Observations in rabbits.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1962, Volume: 67

    Topics: Amidines; Animals; Eye Diseases; Guanethidine; Intraocular Pressure; Ophthalmology; Pupil; Rabbits;

1962
The effects of local administration of guanethidine and BW 467 C 60 on the aqueous humour composition in rabbit.
    Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde, 1967, Volume: 153, Issue:5

    Topics: Animals; Antihypertensive Agents; Aqueous Humor; Chlorides; Female; Glucose; Guanethidine; Intraocul

1967
Outflow facility after guanethidine sulfate administration.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1967, Volume: 78, Issue:3

    Topics: Glaucoma; Guanethidine; Humans; Intraocular Pressure

1967
Long-term trial of local guanethidine in treatment of eye signs of thyroid dysfunction and idiopathic lid retraction.
    British medical journal, 1967, Dec-09, Volume: 4, Issue:5579

    Topics: Edema; Exophthalmos; Eye Manifestations; Eyelids; Female; Guanethidine; Humans; Hyperthyroidism; Hyp

1967
[Behavior of intraocular pressure during long-term treatment with a guanethidine-adrenaline combination].
    Klinische Monatsblatter fur Augenheilkunde, 1983, Volume: 183, Issue:1

    Topics: Adult; Aged; Drug Combinations; Epinephrine; Female; Glaucoma, Open-Angle; Guanethidine; Humans; Int

1983
The aqueous humor dynamics and the biphasic response in intraocular pressure induced by guanethidine and adrenaline in the glaucomatous eye.
    Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie. Albrecht von Graefe's archive for clinical and experimental ophthalmology, 1980, Volume: 214, Issue:4

    Topics: Aqueous Humor; Drug Combinations; Epinephrine; Glaucoma; Guanethidine; Humans; Intraocular Pressure

1980
Maintenance therapy of glaucoma patients with guanethidine (3%) and adrenaline (0.5%) once daily.
    Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie. Albrecht von Graefe's archive for clinical and experimental ophthalmology, 1980, Volume: 214, Issue:4

    Topics: Drug Combinations; Epinephrine; Glaucoma; Guanethidine; Humans; Intraocular Pressure

1980
Verification of the biphasic response in intraocular pressure during treatment of glaucoma patients with 3% guanethidine and 0.5% adrenaline.
    Documenta ophthalmologica. Advances in ophthalmology, 1981, Mar-31, Volume: 51, Issue:1-2

    Topics: Drug Combinations; Epinephrine; Glaucoma; Guanethidine; Humans; Intraocular Pressure; Periodicity

1981
Guanethidine - adrenaline eye drops in glaucoma simplex. Pupil behaviour and response of intraocular pressure.
    Documenta ophthalmologica. Advances in ophthalmology, 1981, Mar-31, Volume: 51, Issue:1-2

    Topics: Drug Combinations; Epinephrine; Glaucoma; Guanethidine; Humans; Intraocular Pressure; Mydriatics; Pe

1981
[A combination of 1% guanethidine and 0.2% epinephrine in drop form to lower IOP in open-angle glaucoma (author's transl)].
    Klinische Monatsblatter fur Augenheilkunde, 1980, Volume: 177, Issue:5

    Topics: Aged; Drug Combinations; Epinephrine; Glaucoma; Guanethidine; Humans; Intraocular Pressure; Middle A

1980
The combination of guanethidine 1% and epinephrine 0.2% in one eye drop (GA-weak) in the treatment of glaucoma.
    Documenta ophthalmologica. Advances in ophthalmology, 1980, Oct-15, Volume: 49, Issue:2

    Topics: Adult; Aged; Aqueous Humor; Drug Combinations; Epinephrine; Female; Glaucoma; Guanethidine; Humans;

1980
Guanethidine--adrenaline eye drops in glaucoma simplex production and outflow of the aqueous humour during a long-term treatment.
    Documenta ophthalmologica. Advances in ophthalmology, 1980, Oct-15, Volume: 49, Issue:2

    Topics: Aqueous Humor; Drug Combinations; Epinephrine; Glaucoma; Guanethidine; Humans; Intraocular Pressure

1980
Prostaglandin mediated inflammatory changes induced by alpha-adrenoceptor stimulation in the sympathectomised rabbit eye.
    Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie. Albrecht von Graefe's archive for clinical and experimental ophthalmology, 1979, Volume: 211, Issue:4

    Topics: Animals; Epinephrine; Eye; Eye Diseases; Female; Guanethidine; Indomethacin; Intraocular Pressure; M

1979
Editorial: A sympathetic approach to open-angle glaucoma.
    The British journal of ophthalmology, 1975, Volume: 59, Issue:6

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Epinephrine; Glaucoma; Guanethidine; Huma

1975
The combination of guanethidine 3% and adrenaline 0.5% in 1 eyedrop (GA) in glaucoma treatment.
    The British journal of ophthalmology, 1979, Volume: 63, Issue:1

    Topics: Adult; Aged; Circadian Rhythm; Drug Administration Schedule; Drug Combinations; Drug Evaluation; Epi

1979
[The effect of sympatholytics on the intraocular pressure in the rabbit eye].
    Bericht uber die Zusammenkunft. Deutsche Ophthalmologische Gesellschaft, 1977, Volume: 74

    Topics: Animals; Bethanidine; Bretylium Tosylate; Guanethidine; Intraocular Pressure; Rabbits; Sympatholytic

1977
A simple grating test for contrast sensitivity: preliminary results indicate value in screening for glaucoma.
    Investigative ophthalmology & visual science, 1978, Volume: 17, Issue:1

    Topics: Adolescent; Adult; Aged; Glaucoma; Guanethidine; Humans; Intraocular Pressure; Male; Middle Aged; Pi

1978
[Antiglaucomatous therapy with reduced concentrations (author's transl)].
    Journal francais d'ophtalmologie, 1978, Volume: 1, Issue:3

    Topics: Drug Therapy, Combination; Epinephrine; Glaucoma; Guanethidine; Humans; Intraocular Pressure; Ophtha

1978
[Approaches in medical treatment in glaucoma (author's transl)].
    Klinische Monatsblatter fur Augenheilkunde, 1977, Volume: 170, Issue:2

    Topics: Acetazolamide; Antihypertensive Agents; Clonidine; Delayed-Action Preparations; Glaucoma; Guanethidi

1977
The principles and technique of medicamentous control of glaucoma.
    Annals of ophthalmology, 1977, Volume: 9, Issue:10

    Topics: Drug Administration Schedule; Glaucoma; Guanethidine; Humans; Intraocular Pressure; Parasympathomime

1977
An improved model of experimentally induced ocular hypertension in the rabbit.
    Investigative ophthalmology, 1976, Volume: 15, Issue:9

    Topics: Animals; Dose-Response Relationship, Drug; Female; Glaucoma; Glucose; Glucose Solution, Hypertonic;

1976
Low centration guanethidine and adrenaline therapy of glaucoma. A preliminary report.
    Transactions of the ophthalmological societies of the United Kingdom, 1976, Volume: 96, Issue:1

    Topics: Administration, Topical; Adult; Aged; Drug Combinations; Epinephrine; Female; Follow-Up Studies; Gla

1976
Ciliary ganglion stimulation. II. Neurogenic, intraocular pathway for excitatory effects on aqueous humor production and outflow.
    Investigative ophthalmology, 1975, Volume: 14, Issue:6

    Topics: Acetylcholine; Animals; Aqueous Humor; Atropine; Bretylium Compounds; Cats; Ciliary Body; Electric S

1975
Effect of adrenaline and guanethidine in reducing intraocular pressure in rabbits' eyes.
    The British journal of ophthalmology, 1975, Volume: 59, Issue:6

    Topics: Animals; Drug Combinations; Epinephrine; Guanethidine; Intraocular Pressure; Male; Rabbits; Time Fac

1975
[Lowering the intraocular pressure by a combination of timolol with adrenergic agents].
    Fortschritte der Ophthalmologie : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft, 1988, Volume: 85, Issue:5

    Topics: Drug Therapy, Combination; Epinephrine; Glaucoma, Open-Angle; Guanethidine; Humans; Intraocular Pres

1988
[Guanethidine/dipivefrin and pilocarpine in the treatment of increased intraocular pressure].
    Klinische Monatsblatter fur Augenheilkunde, 1987, Volume: 190, Issue:2

    Topics: Drug Therapy, Combination; Epinephrine; Glaucoma, Open-Angle; Guanethidine; Humans; Intraocular Pres

1987
[Experiences with the effectiveness and tolerance of guanethidine/dipivefrin-AT in the treatment of increased intraocular pressure].
    Klinische Monatsblatter fur Augenheilkunde, 1986, Volume: 188, Issue:1

    Topics: Drug Therapy, Combination; Epinephrine; Glaucoma, Open-Angle; Guanethidine; Humans; Intraocular Pres

1986
[Clinical study of the action of intraocular pressure and aqueous humor flow of a solution of 5-percent ismelin and of 5-percent ismelin with l-percent pilocarpine].
    Archives d'ophtalmologie et revue generale d'ophtalmologie, 1969, Volume: 29, Issue:4

    Topics: Aqueous Humor; Glaucoma; Guanethidine; Humans; Intraocular Pressure; Pilocarpine

1969
Adrenergic supersensitization as a therapeutic tool in glaucoma.
    Transactions of the ophthalmological societies of the United Kingdom, 1974, Volume: 94, Issue:2

    Topics: Drug Combinations; Drug Eruptions; Drug Hypersensitivity; Epinephrine; Female; Glaucoma; Guanethidin

1974
[Adrenergic blockade in endocrine exophthalmus and glaucoma].
    Nordisk medicin, 1971, Apr-01, Volume: 85, Issue:13

    Topics: Adrenergic beta-Antagonists; Exophthalmos; Glaucoma; Guanethidine; Humans; Intraocular Pressure

1971
The effect of topically applied guanethidine sulphate on pupil and tension responses of the rabbit eye to (--)-adrenaline bitartrate.
    Experimental eye research, 1974, Volume: 19, Issue:1

    Topics: Animals; Biometry; Depression, Chemical; Drug Synergism; Epinephrine; Guanethidine; Intraocular Pres

1974
Guanethidine and glaucoma.
    Transactions of the ophthalmological societies of the United Kingdom, 1974, Volume: 94, Issue:2

    Topics: Acetazolamide; Drug Synergism; Epinephrine; Glaucoma; Guanethidine; Humans; Intraocular Pressure; Op

1974
Local guanethidine drops in the treatment of chronic simple glaucoma.
    Indian journal of ophthalmology, 1972, Volume: 20, Issue:3

    Topics: Glaucoma; Guanethidine; Humans; Intraocular Pressure; Ophthalmic Solutions

1972
[Effect of treatment by combination of guanethidine (ismelin) and epinephrine on intraocular pressure].
    Nippon Ganka Gakkai zasshi, 1973, Volume: 77, Issue:7

    Topics: Drug Synergism; Epinephrine; Guanethidine; Humans; Intraocular Pressure

1973
The induction of aqueous humor formation by the use of Ach+eserine.
    Investigative ophthalmology, 1973, Volume: 12, Issue:12

    Topics: Acetylcholine; Animals; Aqueous Humor; Atropine; Cats; Ganglia, Autonomic; Guanethidine; Hexamethoni

1973
[Has guanethidine a place in the treatment of ocular hypertension?].
    Bulletin de la Societe belge d'ophtalmologie, 1973, Nov-25, Volume: 165, Issue:0

    Topics: Depression, Chemical; Glaucoma; Guanethidine; Humans; Intraocular Pressure; Time Factors

1973
Pupil-block. Its mechanism and prevention. II. Dilating the pupil by a mydriaticum-ismelin combination. A procedure with minimal risk.
    Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde, 1971, Volume: 163, Issue:4

    Topics: Dilatation; Eye Diseases; Glaucoma; Guanethidine; Humans; Intraocular Pressure; Mydriatics; Pupil; S

1971
[Guanethidine in the glucoma therapy].
    Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie. Albrecht von Graefe's archive for clinical and experimental ophthalmology, 1968, Volume: 176, Issue:1

    Topics: Depression, Chemical; Glaucoma; Guanethidine; Humans; Intraocular Pressure; Pilocarpine

1968
[Ismelin eye drops in glaucoma patients. Tonometric study].
    Hospital (Rio de Janeiro, Brazil), 1970, Volume: 77, Issue:3

    Topics: Adolescent; Adult; Glaucoma; Guanethidine; Humans; Intraocular Pressure; Tonometry, Ocular

1970
[Influence of a 5 per cent ismelin solution on intraocular tension in glaucoma patients].
    Klinika oczna, 1970, Volume: 40, Issue:3

    Topics: Adult; Aged; Chronic Disease; Female; Glaucoma; Guanethidine; Humans; Intraocular Pressure; Male; Mi

1970
[Supersensitivity of outflow facility of epinephrine in open angle glaucoma treated with guanethidine].
    Nippon Ganka Gakkai zasshi, 1970, Jan-10, Volume: 74, Issue:1

    Topics: Adult; Aged; Aqueous Humor; Epinephrine; Female; Glaucoma; Guanethidine; Humans; Intraocular Pressur

1970
Effects of systemically administered drugs on intraocular pressure in rabbits.
    Arzneimittel-Forschung, 1970, Volume: 20, Issue:8

    Topics: Acetazolamide; Amphetamine; Animals; Anti-Inflammatory Agents; Antihypertensive Agents; Blood Pressu

1970
[Study of the action of Ismelin eye drops in normal and glaucomatous eyes].
    Revista brasileira de oftalmologia, 1971, Volume: 30, Issue:2

    Topics: Adolescent; Adult; Aged; Female; Glaucoma; Guanethidine; Humans; Intraocular Pressure; Male; Middle

1971
[Guanethidine in combination with pilocarpine in glaucoma simplex].
    Klinische Monatsblatter fur Augenheilkunde, 1967, Volume: 150, Issue:6

    Topics: Carbachol; Drug Synergism; Glaucoma; Guanethidine; Humans; Intraocular Pressure; Ophthalmic Solution

1967
[The effects of the Sanotensin eyedrops].
    Orvosi hetilap, 1968, Jul-07, Volume: 109, Issue:27

    Topics: Glaucoma; Guanethidine; Humans; Intraocular Pressure; Ophthalmic Solutions

1968
Sympathetic control of aqueous secretion in man.
    The British journal of ophthalmology, 1969, Volume: 53, Issue:1

    Topics: Adult; Aqueous Humor; Catecholamines; Guanethidine; Horner Syndrome; Humans; Intraocular Pressure; M

1969
[Use of blockers of the sympathetic nerves in opthalmology].
    Revista brasileira de oftalmologia, 1969, Volume: 28, Issue:1

    Topics: Adolescent; Adult; Aged; Guanethidine; Humans; Intraocular Pressure; Methods; Middle Aged; Nervous S

1969
The mechanism of action of guanethidine on aqueous humor dynamics.
    The Journal of pharmacology and experimental therapeutics, 1965, Volume: 150, Issue:3

    Topics: Animals; Aqueous Humor; Blood Pressure; Catecholamines; Ciliary Body; Guanethidine; Heart Rate; In V

1965
[The ocular hypotensive mechanism of action of guanethidine].
    Annali di ottalmologia e clinica oculistica, 1965, Volume: 91, Issue:8

    Topics: Adolescent; Adult; Aged; Female; Guanethidine; Humans; Intraocular Pressure; Middle Aged

1965
[On the effectiveness of prolonged guanethidine therapy on intraocular pressure].
    Bollettino d'oculistica, 1966, Volume: 45, Issue:5

    Topics: Animals; Glaucoma; Guanethidine; Humans; Intraocular Pressure; Rabbits

1966