Page last updated: 2024-10-28

guanethidine and Idiopathic Parkinson Disease

guanethidine has been researched along with Idiopathic Parkinson Disease in 3 studies

Guanethidine: An antihypertensive agent that acts by inhibiting selectively transmission in post-ganglionic adrenergic nerves. It is believed to act mainly by preventing the release of norepinephrine at nerve endings and causes depletion of norepinephrine in peripheral sympathetic nerve terminals as well as in tissues.
guanethidine : A member of the class of guanidines in which one of the hydrogens of the amino group has been replaced by a 2-azocan-1-ylethyl group.
guanethidine sulfate : A organic sulfate salt composed of two molecules of guanethidine and one of sulfuric acid.

Research Excerpts

ExcerptRelevanceReference
"This could be the explantion for the orthostatic hypotension found in patients taking L-dopa for Parkinsonism."2.63Action of dopamine on the human iris. ( Calne, DB; Spiers, AS, 1969)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19903 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hunter, KR1
Stern, GM1
Laurence, DR1
Nelson, SR1
Walaszek, EJ1
Spiers, AS1
Calne, DB1

Reviews

1 review available for guanethidine and Idiopathic Parkinson Disease

ArticleYear
Pharmacology of the central nervous system.
    Progress in neurology and psychiatry, 1968, Volume: 23

    Topics: Abnormalities, Drug-Induced; Acetylcholine; Adrenocorticotropic Hormone; Amphetamine; Anger; Angiote

1968

Trials

1 trial available for guanethidine and Idiopathic Parkinson Disease

ArticleYear
Action of dopamine on the human iris.
    British medical journal, 1969, Nov-08, Volume: 4, Issue:5679

    Topics: Adult; Aged; Dihydroxyphenylalanine; Dilatation; Dopamine; Dopamine Antagonists; Female; Guanethidin

1969

Other Studies

1 other study available for guanethidine and Idiopathic Parkinson Disease

ArticleYear
Use of levodopa with other drugs.
    Lancet (London, England), 1970, Dec-19, Volume: 2, Issue:7686

    Topics: Adult; Aged; Antidepressive Agents; Antiemetics; Digoxin; Dihydroxyphenylalanine; Diuretics; Drug An

1970