guanethidine has been researched along with Hypotension in 49 studies
Guanethidine: An antihypertensive agent that acts by inhibiting selectively transmission in post-ganglionic adrenergic nerves. It is believed to act mainly by preventing the release of norepinephrine at nerve endings and causes depletion of norepinephrine in peripheral sympathetic nerve terminals as well as in tissues.
guanethidine : A member of the class of guanidines in which one of the hydrogens of the amino group has been replaced by a 2-azocan-1-ylethyl group.
guanethidine sulfate : A organic sulfate salt composed of two molecules of guanethidine and one of sulfuric acid.
Hypotension: Abnormally low BLOOD PRESSURE that can result in inadequate blood flow to the brain and other vital organs. Common symptom is DIZZINESS but greater negative impacts on the body occur when there is prolonged depravation of oxygen and nutrients.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Intravenous injection of paeoniflorin, a glycoside purified from the root of Paeonia lactiflora, reversed guanethidine-induced hypotension in Wistar rats." | 7.70 | Paeoniflorin reverses guanethidine-induced hypotension via activation of central adenosine A1 receptors in Wistar rats. ( Cheng, JT; Hsu, FL; Wang, CJ, 1999) |
| "A 25-year-old female developed causalgia following a nerve injury in the left hand, and this was treated successfully with a series of intravenous guanethidine blocks." | 7.67 | A case of prolonged hypotension following intravenous guanethidine block. ( Carli, F; Milaszkiewicz, R; Sharpe, E, 1987) |
| "When used in the treatment of hypertension propranolol is at least of similar potency to bethanidine, guanethidine, and methyldopa." | 7.65 | Treatment of hypertension with propranolol. ( Gillam, PM; Prichard, BN, 1969) |
| " Intravenous injection of paeoniflorin, a glycoside purified from the root of Paeonia lactiflora, reversed guanethidine-induced hypotension in Wistar rats." | 3.70 | Paeoniflorin reverses guanethidine-induced hypotension via activation of central adenosine A1 receptors in Wistar rats. ( Cheng, JT; Hsu, FL; Wang, CJ, 1999) |
| "A 25-year-old female developed causalgia following a nerve injury in the left hand, and this was treated successfully with a series of intravenous guanethidine blocks." | 3.67 | A case of prolonged hypotension following intravenous guanethidine block. ( Carli, F; Milaszkiewicz, R; Sharpe, E, 1987) |
| "Symptoms due to orthostatic and exertional hypotension occurred in 23-4 per cent of 448 hypertensive patients treated with guanethidine, debrisoquine, or bethanidine." | 3.65 | Factors predisposing to postural hypotensive symptoms in the treatment of high blood pressure. ( Smith, AJ; Talbot, S, 1975) |
| "When used in the treatment of hypertension propranolol is at least of similar potency to bethanidine, guanethidine, and methyldopa." | 3.65 | Treatment of hypertension with propranolol. ( Gillam, PM; Prichard, BN, 1969) |
| " Other reported effects are toxic confusional states and psychotic reactions." | 2.36 | Psychiatric side effects of antihypertensive drugs other than reserpine. ( Fleminger, R; Paykel, ES; Watson, JP, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 48 (97.96) | 18.7374 |
| 1990's | 1 (2.04) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Skulnick, HI | 1 |
| Ludens, JH | 1 |
| Wendling, MG | 1 |
| Glenn, EM | 1 |
| Rohloff, NA | 1 |
| Smith, RJ | 1 |
| Wierenga, W | 1 |
| LAURICELLA, E | 1 |
| MAGGIORA-VERGANO, T | 1 |
| LICHTLEN, P | 2 |
| BUEHLMANN, A | 2 |
| SCHAUB, F | 2 |
| VELLES AGUIRRE, LI | 1 |
| BALPARDA, H | 1 |
| AZAR, D | 1 |
| VOZZI, CD | 1 |
| GUTIERREZ MARQUEZ, R | 1 |
| BRICAUD, H | 1 |
| DALLOCCHIO, M | 1 |
| SAUTRON, J | 1 |
| BROUSTET, P | 1 |
| HOLLOWAY, KB | 1 |
| HOLMES, F | 1 |
| HIDER, CF | 1 |
| PERRICONI, H | 1 |
| DEL RIO, CA | 1 |
| MAZZEI, CM | 1 |
| BADOUAL, J | 1 |
| HUEGIN, W | 1 |
| MCGIFF, JC | 1 |
| CHU, CC | 1 |
| WANG, CK | 1 |
| WANG, XL | 1 |
| TING, KS | 1 |
| RIPKA, O | 1 |
| MALIS, F | 1 |
| BOETTIGER, LE | 1 |
| MALMBORG, RO | 1 |
| MICHAELI, EW | 1 |
| HERMANSEN, K | 1 |
| LURIA, MH | 1 |
| MILLER, AJ | 1 |
| KAPLAN, BM | 1 |
| WALDSTEIN, SS | 1 |
| WEST, GH | 1 |
| LEE, WY | 1 |
| BRONSKY, D | 1 |
| SCHULTZ, FB | 1 |
| BEWLEY, TH | 1 |
| DUSTAN, HP | 1 |
| PAGE, IH | 1 |
| KRUSHKOV, I | 1 |
| STUMP, JM | 1 |
| FLEMING, WW | 1 |
| MIELE, E | 2 |
| MARMO, E | 1 |
| PREZIOSI, P | 1 |
| Paykel, ES | 1 |
| Fleminger, R | 1 |
| Watson, JP | 1 |
| Baum, T | 1 |
| Sabin, C | 1 |
| Moran, RM | 1 |
| Cheng, JT | 1 |
| Wang, CJ | 1 |
| Hsu, FL | 1 |
| Talbot, S | 2 |
| Smith, AJ | 1 |
| Shkhvatsabaya, IK | 1 |
| Erina, EV | 1 |
| Al'musaui, AI | 1 |
| Bhargava, KP | 1 |
| Srivastava, VK | 1 |
| Barthwal, JP | 1 |
| Sinha, JN | 1 |
| O'Malley, BC | 1 |
| Bing, RH | 1 |
| Voigts, AL | 1 |
| Mark, AL | 1 |
| Johannsen, J | 1 |
| Schmid, PG | 1 |
| Heistad, DD | 1 |
| Abboud, FM | 1 |
| Terekova, R | 1 |
| Shenderov, SM | 1 |
| Terek, I | 1 |
| Sharpe, E | 1 |
| Milaszkiewicz, R | 1 |
| Carli, F | 1 |
| Hunter, KR | 1 |
| Stern, GM | 1 |
| Laurence, DR | 1 |
| Kobinger, W | 1 |
| Cummings, JR | 1 |
| Welter, AN | 1 |
| Grace, JL | 1 |
| Gray, WD | 1 |
| De Natale, G | 1 |
| Glavas, E | 1 |
| Trajkov, T | 1 |
| Nikodijeviç, B | 1 |
| Dalen, JE | 1 |
| Alpert, JS | 1 |
| Cohn, LH | 1 |
| Black, H | 1 |
| Collins, JJ | 1 |
| Heinrich, F | 1 |
| Carstens, E | 1 |
| Ekbom, KA | 1 |
| MacLennan, WJ | 1 |
| Wenzel, DG | 1 |
| Azmeh, N | 1 |
| Clark, IJ | 1 |
| Subbu, VS | 1 |
| Shaw, J | 1 |
| Hunyor, SN | 1 |
| Korner, PI | 1 |
| Hall, K | 1 |
| Hökfelt, B | 1 |
| Higgins, JT | 1 |
| Prichard, BN | 1 |
| Gillam, PM | 1 |
3 reviews available for guanethidine and Hypotension
| Article | Year |
|---|---|
[PROBLEMS OF ANESTHESIA IN PATIENTS UNDER TREATMENT OF HYPERTENSION].
Topics: Anesthesia; Antihypertensive Agents; Bretylium Compounds; Cardiovascular Diseases; Chlorothiazide; C | 1963 |
[PHARMACOLOGY OF SOME NEW HYPOTENSIVE DRUGS].
Topics: Antihypertensive Agents; Bretylium Compounds; Carboxy-Lyases; Chemistry, Pharmaceutical; Enzyme Inhi | 1964 |
Psychiatric side effects of antihypertensive drugs other than reserpine.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Anxiety; Bethanidine; Clonidine; Debrisoquin; | 1982 |
1 trial available for guanethidine and Hypotension
| Article | Year |
|---|---|
Letter: Debrisoquine, guanethidine, and bethanidine in hypertension.
Topics: Antihypertensive Agents; Bethanidine; Debrisoquin; Diarrhea; Guanethidine; Guanidines; Humans; Hyper | 1975 |
45 other studies available for guanethidine and Hypotension
| Article | Year |
|---|---|
Pyrimidinones. 3. N-substituted 6-phenylpyrimidinones and pyrimidinediones with diuretic/hypotensive and antiinflammatory activity.
Topics: Animals; Anti-Inflammatory Agents; Antiviral Agents; Arthritis; Diuresis; Dose-Response Relationship | 1986 |
[The hypotensive action of a guanethidine derivative in hypertensive gestoses].
Topics: Amidines; Antihypertensive Agents; Female; Guanethidine; Hypertension; Hypotension; Pre-Eclampsia; P | 1960 |
[On the mechanism of the blood pressure lowering action of intravenously administered guanethidine].
Topics: Administration, Intravenous; Amidines; Antihypertensive Agents; Blood Pressure; Guanethidine; Hypote | 1961 |
[Clinical and experimental studies on the hypotensive effect of guanethidine].
Topics: Amidines; Antihypertensive Agents; Guanethidine; Hypotension | 1960 |
[Hypotensive action of guanethidine].
Topics: Amidines; Guanethidine; Hypertension; Hypotension | 1961 |
[A new hypotensive drug: guanethidine. Its association with the hydralazines].
Topics: Amidines; Antihypertensive Agents; Guanethidine; Hydralazine; Hypertension; Hypotension | 1961 |
Guanethidine in hypotensive anaesthesia; clinical study in patients undergoing microsurgery of the middle ear.
Topics: Amidines; Anesthesia; Anesthesiology; Antihypertensive Agents; Ear, Middle; Guanethidine; Hypotensio | 1961 |
[Methyl-dopa and mebutamate. Hypotensive action of guanethidine. Comparative study].
Topics: Anti-Anxiety Agents; Antihypertensive Agents; Carbamates; Dihydroxyphenylalanine; Guanethidine; Hype | 1963 |
[New hypotensive medications: guanethidine, alphamethyldopa, mecamylamine].
Topics: Antihypertensive Agents; Guanethidine; Humans; Hypotension; Mecamylamine; Methyldopa | 1963 |
ALLOCATION OF CARDIAC OUTPUT TO LIMB AND KIDNEY DURING HYPOTENSIVE PROCEDURES.
Topics: Animals; Blood Circulation; Blood Flow Velocity; Cardiac Output; Carotid Sinus; Dogs; Femoral Vein; | 1963 |
[THE THREE PHASES OF BLOOD PRESSURE CHANGES AFTER INTRAVENOUS GUANETHIDINE TO CHLORALOSED CATS].
Topics: Blood Pressure; Cats; Chloralose; Guanethidine; Hypotension; Injections, Intravenous; Norepinephrine | 1963 |
[GUANETHIDINE. A NEW TYPE HYPOTENSIVE DRUG].
Topics: Abdomen; Antihypertensive Agents; Bradycardia; Fundus Oculi; Guanethidine; Humans; Hypertension; Hyp | 1963 |
[SEVERE NEUROLOGICAL SIDE-EFFECTS IN HYPOTENSION THERAPY].
Topics: Amobarbital; Antihypertensive Agents; Arteriosclerosis; Chlorothiazide; Chlorthalidone; Guanethidine | 1964 |
SOME PHARMACOLOGICAL PROPERTIES OF A NEW ADRENERGIC NEURONE-BLOCKING AGENT, N-(BETA-GUANIDINOETHYL)-HEXAHYDROBENZO-(D)-AZOCINE SULPHATE (PH 881-7).
Topics: Adrenergic Agents; Autonomic Nervous System; Azocines; Blood Pressure; Blood Pressure Determination; | 1963 |
SUCCESSFUL THERAPY OF PROLONGED HYPOTENSION WITH AN ADRENERGIC BETA-RECEPTOR BLOCKING AGENT.
Topics: Adrenergic beta-Antagonists; Blood Volume; Gastrointestinal Hemorrhage; Guanethidine; Hemorrhagic Di | 1964 |
GUANETHIDINE IN HYPERTHYROIDISM.
Topics: Catecholamines; Drug Therapy; Guanethidine; Hyperthyroidism; Hypotension; Hypotension, Orthostatic; | 1964 |
A NEW HYPOTENSIVE DRUG COMBINATION (GUANETHIDINE-HYDROCHLOROTHIAZIDE).
Topics: Biomedical Research; Drug Combinations; Drug Therapy; Geriatrics; Guanethidine; Hydrochlorothiazide; | 1964 |
TO-DAY'S DRUGS. BETHANIDINE SULPHATE.
Topics: Antihypertensive Agents; Bethanidine; Bretylium Compounds; Chemistry, Pharmaceutical; Depression; De | 1964 |
SOME FACTORS IN RENAL AND RENOPRIVAL HYPERTENSION.
Topics: Blood; Blood Pressure; Blood Proteins; Blood Volume; Chlorothiazide; Cholesterol; Drug Therapy; Guan | 1964 |
THE EFFECT OF GUANETHIDINE, COCAINE, AND RESERPINE ON THE HYPOTENSIVE ACTION OF THIOPENTAL.
Topics: Blood Pressure; Cocaine; Dogs; Guanethidine; Hypotension; Norepinephrine; Pharmacology; Research; Re | 1965 |
[Diverse effect of hydrochlorothiazide in relation to the hypotensive activity of reserpine, rescinnamine, syrosingopine, 1, 4-dihydrazino-phthlazine (alone or associated with reserpine), hexamethonium and guanethidine].
Topics: Alkaloids; Antihypertensive Agents; Blood Pressure; Blood Pressure Determination; Chlorothiazide; Gu | 1961 |
Comparison of hypotensive, orthostatic and sympathetic inhibitory actions of antihypertensive drugs in rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Clonidine; Diazepam; Guanethidine; Heart Rate; Hyd | 1981 |
Paeoniflorin reverses guanethidine-induced hypotension via activation of central adenosine A1 receptors in Wistar rats.
Topics: Adrenergic Agents; Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzoates; Blood Pressure; Brid | 1999 |
Factors predisposing to postural hypotensive symptoms in the treatment of high blood pressure.
Topics: Bethanidine; Cardiomegaly; Circadian Rhythm; Debrisoquin; Female; Guanethidine; Guanidines; Heart Ra | 1975 |
Changes in venous and arterial tone during treatment with antihypertensive agents.
Topics: Adult; Antihypertensive Agents; Arteries; Blood Pressure; Guanethidine; Hemodynamics; Humans; Hypert | 1977 |
Significance of spinal autonomic loci in post coronary ligation arrhythmia.
Topics: Animals; Arrhythmias, Cardiac; Autonomic Nervous System; Catecholamines; Chloralose; Chlorisondamine | 1976 |
Efferent pathways of the coronary chemoreflex.
Topics: Animals; Atropine; Cardiovascular System; Coronary Vessels; Dogs; Guanethidine; Hindlimb; Hypotensio | 1975 |
[Constrictor reaction to transmural electric stimulation of the isolated femoral artery and its branches in chronic arterial hypotension].
Topics: Animals; Chronic Disease; Electric Stimulation; Femoral Artery; Guanethidine; Hypotension; Norepinep | 1988 |
A case of prolonged hypotension following intravenous guanethidine block.
Topics: Adult; Anesthesia, Intravenous; Autonomic Nerve Block; Causalgia; Female; Guanethidine; Hand; Humans | 1987 |
Use of levodopa with other drugs.
Topics: Adult; Aged; Antidepressive Agents; Antiemetics; Digoxin; Dihydroxyphenylalanine; Diuretics; Drug An | 1970 |
[On the mechanism of action of a new antihypertensive substance with imidazoline structure].
Topics: Animals; Antihypertensive Agents; Bradycardia; Bretylium Compounds; Cats; Depression, Chemical; Elec | 1967 |
Angiotensin blocking actions of guancydine.
Topics: Angiotensin II; Animals; Atropine; Blood Flow Velocity; Blood Pressure; Carotid Arteries; Epinephrin | 1969 |
Modification by guanethidine and nethalide of the pressor effects of bradykinin in the rat.
Topics: Adrenalectomy; Angiotensin II; Animals; Blood Pressure; Bradykinin; Epinephrine; Ethanolamines; Guan | 1966 |
Cardiovascular effects of pyrogallol and 4-tropoloneacetamide.
Topics: Animals; Blood Pressure; Bretylium Compounds; Cycloparaffins; Female; Guanethidine; Hypotension; Ket | 1967 |
Dissection of the thoracic aorta. Medical or surgical therapy?
Topics: Adult; Aged; Aorta, Thoracic; Aortic Aneurysm; Aortic Valve Insufficiency; Autonomic Agents; Blood P | 1974 |
[Problems in the establishment of indications for treatment of aortic (thoracic and abdominal) aneurysms, from a medical viewpoint (author's transl)].
Topics: Aged; Aorta, Abdominal; Aorta, Thoracic; Aortic Aneurysm; Aortic Rupture; Guanethidine; Humans; Hypo | 1974 |
[Antihypertensive agents].
Topics: Acetazolamide; Antihypertensive Agents; Bis-Trimethylammonium Compounds; Bretylium Compounds; Chlori | 1972 |
Scotoma due to arterial hypotension.
Topics: Guanethidine; Humans; Hydrochlorothiazide; Hypertension; Hypotension; Male; Middle Aged; Scotoma; Sy | 1973 |
Drug interactions.
Topics: 1-Propanol; Acute Kidney Injury; Aged; Albumins; Antidepressive Agents; Antihypertensive Agents; Ben | 1974 |
Studies on the acute and chronic depressor actions of nicotine in the rat.
Topics: Animals; Blood Pressure; Carbamates; Female; Ganglionic Stimulants; Guanethidine; Hypertension, Rena | 1971 |
The influence of guanethidine pretreatment upon the haemodynamics of dogs under haemorrhagic hypotension.
Topics: Animals; Dogs; Guanethidine; Hemodynamics; Hemorrhage; Hypotension; Premedication | 1971 |
The peripheral circulatory effects of clonidine and their role in the production of arterial hypotension.
Topics: Adrenalectomy; Aniline Compounds; Animals; Atropine; Autonomic Nerve Block; Blood Pressure; Cardiac | 1971 |
Studies on aldosterone production and sodium metabolism in relation to sympathetic nervous function in man.
Topics: Adult; Aldosterone; Guanethidine; Humans; Hypotension; In Vitro Techniques; Male; Middle Aged; Norep | 1966 |
Escape from sodium-retaining effects of deoxycorticosterone in hypotensive and hypertensive dogs.
Topics: Aminohippuric Acids; Animals; Blood Pressure; Creatinine; Desoxycorticosterone; Dogs; Ephedrine; Fem | 1970 |
Treatment of hypertension with propranolol.
Topics: Blood Pressure; Cardiac Output; Female; Guanethidine; Guanidines; Humans; Hypertension; Hypotension; | 1969 |