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guanethidine and Hypertension, Malignant

guanethidine has been researched along with Hypertension, Malignant in 45 studies

Guanethidine: An antihypertensive agent that acts by inhibiting selectively transmission in post-ganglionic adrenergic nerves. It is believed to act mainly by preventing the release of norepinephrine at nerve endings and causes depletion of norepinephrine in peripheral sympathetic nerve terminals as well as in tissues.
guanethidine : A member of the class of guanidines in which one of the hydrogens of the amino group has been replaced by a 2-azocan-1-ylethyl group.
guanethidine sulfate : A organic sulfate salt composed of two molecules of guanethidine and one of sulfuric acid.

Hypertension, Malignant: A condition of markedly elevated BLOOD PRESSURE with DIASTOLIC PRESSURE usually greater than 120 mm Hg. Malignant hypertension is characterized by widespread vascular damage, PAPILLEDEMA, retinopathy, HYPERTENSIVE ENCEPHALOPATHY, and renal dysfunction.

Research Excerpts

ExcerptRelevanceReference
"Twenty-six patients were selected for treatment with minoxidil on the basis of hypertension which could not be controlled either because of (1) drug failures and/or (2) side effects of drugs."7.65Minoxidil in severe hypertension: value when conventional drugs have failed. ( Dormois, JC; Nies, AS; Young, JL, 1975)
"Twenty-six patients were selected for treatment with minoxidil on the basis of hypertension which could not be controlled either because of (1) drug failures and/or (2) side effects of drugs."3.65Minoxidil in severe hypertension: value when conventional drugs have failed. ( Dormois, JC; Nies, AS; Young, JL, 1975)

Research

Studies (45)

TimeframeStudies, this research(%)All Research%
pre-199045 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
CHOA, GH1
RASSIM, HS1
WONG, WL1
PEDERSEN, J1
LINDENEG, O1
FISCHER, S1
CLAURE, H1
GARCIA, H1
ACCHIARDO, S1
SEBRANJOBRIZ, F1
GILL, JR1
GEORGE, JM1
SOLOMON, A1
BARTTER, FC1
CHIRONE, E1
PRIMROSE, J1
PALMER, KN1
Moyer, JH2
Brown, BT1
Carrion, HM1
Politano, VA1
Haas, Th1
Denkl, P1
Diethelm, AG1
Hartley, MW1
Aldrete, JS1
Sterling, WA1
Morgan, JM1
Dormois, JC1
Young, JL1
Nies, AS1
Curry, CL1
Seedat, YK1
Philipp, T1
Nast, HP1
Hamilton, M2
Harris, PW1
Mühlberg, H1
Mühlberg, G1
Bock, KD2
Mashaly, M1
el-Ebrashy, N1
Higazi, AM1
el-Din Moustafa, S1
Abul-Einen, M1
Zimmerman, SW1
Bergin, JJ1
Moser, M2
Siegler, RL1
Muldowney, FP1
Kim, KE1
Onesti, G1
Swartz, C1
Ahearn, DJ1
Grim, CE1
Woods, JW1
Blythe, WB1
Huffines, WD1
Voudoukis, IJ1
Caldwell, JR1
Froment, R1
Froment, A1
Zech, P1
Tucker, RM1
Hunt, JC1
Cranston, WI2
Vaamonde, CA1
David, NJ1
Palmer, RF1
McAllister, RG1
Van Way, CW1
Dayani, K1
Anderson, WJ1
Temple, E1
Michelakis, AM1
Coppage, WS1
Oates, JA1
Luchetti, L1
Consoli, G1
Marinosci, A1
Juchems, R1
Pomerantz, HZ1
Repetto, S1
Rezzonico, A1
Gervasini, N1
Athanassiadis, D1
Juel-Jensen, BE1
Oliver, DO1

Reviews

6 reviews available for guanethidine and Hypertension, Malignant

ArticleYear
[MALIGNANT HYPERTENSION].
    Il Policlinico. Sezione pratica, 1964, Mar-02, Volume: 71

    Topics: Adrenalectomy; Angiotensins; Bretylium Compounds; Chlorisondamine; Diagnosis; Diet, Sodium-Restricte

1964
Drug systems approach to hypertension.
    Pennsylvania medicine, 1984, Volume: 87, Issue:5

    Topics: Captopril; Clonidine; Drug Combinations; Drug Therapy, Combination; Guanethidine; Humans; Hydralazin

1984
Recent advances in the medical and surgical treatment of hypertension.
    The Medical clinics of North America, 1968, Volume: 52, Issue:5

    Topics: Adrenocortical Hyperfunction; Antihypertensive Agents; Diet, Sodium-Restricted; Diuretics; Ethacryni

1968
Advances in medicine.
    The Practitioner, 1968, Volume: 201, Issue:204

    Topics: Acute Kidney Injury; Asthma; Blindness; Catecholamines; Contraceptives, Oral; Coronary Disease; Guan

1968
Treatment of "hypertensive encephalopathy" (accelerated hypertension). II.
    American heart journal, 1969, Volume: 77, Issue:5

    Topics: Antihypertensive Agents; Diazoxide; Glomerulonephritis; Guanethidine; Humans; Hydralazine; Hypertens

1969
Hypertensive emergencies.
    The Medical clinics of North America, 1971, Volume: 55, Issue:2

    Topics: Brain Diseases; Guanethidine; Hypertension, Malignant; Kidney; Reserpine; Trimethaphan

1971

Trials

2 trials available for guanethidine and Hypertension, Malignant

ArticleYear
[Ambulant long-term treatment of arterial hypertension].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1965, Aug-01, Volume: 20, Issue:15

    Topics: Animals; Antihypertensive Agents; Chlorothiazide; Clinical Trials as Topic; Diuretics; Female; Gangl

1965
Treatment of hypertension--a pragmatic approach.
    Preventive medicine, 1974, Volume: 3, Issue:3

    Topics: Antihypertensive Agents; Cerebrovascular Disorders; Clinical Trials as Topic; Erectile Dysfunction;

1974

Other Studies

37 other studies available for guanethidine and Hypertension, Malignant

ArticleYear
[Case report on the treatment of malignant hypertension].
    Munchener medizinische Wochenschrift (1950), 1962, Nov-30, Volume: 104

    Topics: Chlorthalidone; Guanethidine; Humans; Hypertension, Malignant

1962
THROMBO-OBLITERATIVE VASCULAR DISEASE OF EARLY ONSET AND LONG DURATION.
    British heart journal, 1963, Volume: 25

    Topics: Angiography; Aorta; Aorta, Abdominal; Arteriosclerosis Obliterans; Asian People; Guanethidine; Human

1963
[ACUTE MALIGNANT HYPERTENSION WITH SECONDARY ALDOSTERONISM. A CASE IN A 31-YEAR-OLD MAN WITH CONGENITAL UNILATERAL RENAL HYPOPLASIA].
    Ugeskrift for laeger, 1964, Jan-16, Volume: 126

    Topics: Alkalosis; Antihypertensive Agents; Blood Chemical Analysis; Congenital Abnormalities; Guanethidine;

1964
[EVOLUTION OF CHRONIC NEPHROPATHS WITH SEVERE OR MALIGNANT HYPERTENSION UNDER TREATMENT WITH GUANETHIDINE SULPHATE].
    Revista medica de Chile, 1963, Volume: 91

    Topics: Adolescent; Cerebral Hemorrhage; Guanethidine; Hypertension; Hypertension, Malignant; Hypertension,

1963
[TREATMENT OF HYPERTENSION WITH HYGROTON-RESERPINE].
    Medicina clinica, 1963, Volume: 41

    Topics: Arteriosclerosis; Chlorthalidone; Clinical Laboratory Techniques; Electrocardiography; Guanethidine;

1963
HYPERALDOSTERONISM AND RENAL SODIUM LOSS REVERSED BY DRUG TREATMENT FOR MALIGNANT HYPERTENSION.
    The New England journal of medicine, 1964, May-21, Volume: 270

    Topics: Blood Chemical Analysis; Chlorambucil; Guanethidine; Humans; Hydralazine; Hyperaldosteronism; Hypert

1964
MECHANISM OF PRODUCTION OF PAPILLOEDEMA.
    The British journal of ophthalmology, 1964, Volume: 48

    Topics: Astrocytoma; Drug Therapy; Glaucoma; Guanethidine; Humans; Hypertension; Hypertension, Malignant; In

1964
THE CHOICE OF HYPOTENSIVE AGENTS.
    The Practitioner, 1964, Volume: 193

    Topics: Antihypertensive Agents; Carboxy-Lyases; Chlorothiazide; Drug Therapy; Ganglionic Blockers; Guanethi

1964
Use of sympatholytic and vasodilator drugs.
    Pennsylvania medicine, 1984, Volume: 87, Issue:1

    Topics: Adrenergic beta-Antagonists; Clonidine; Diuretics; Drug Therapy, Combination; Guanethidine; Humans;

1984
Guanethidine sulfate in the prevention of autonomic hyperreflexia.
    The Journal of urology, 1979, Volume: 122, Issue:1

    Topics: Autonomic Nervous System; Blood Pressure; Guanethidine; Humans; Hypertension, Malignant; Nervous Sys

1979
[Therapy of hypertensive crises].
    Fortschritte der Medizin, 1977, Apr-21, Volume: 95, Issue:15

    Topics: Acute Disease; Adrenal Gland Neoplasms; Antihypertensive Agents; Clonidine; Diazoxide; Dihydralazine

1977
Treatment of accelerated hypertension and end stage renal failure by bilateral nephrectomy and renal transplantation.
    Surgery, gynecology & obstetrics, 1975, Volume: 140, Issue:2

    Topics: Acute Kidney Injury; Adult; Biopsy; Blood Pressure; Child; Creatinine; Female; Graft Rejection; Guan

1975
Minoxidil in severe hypertension: value when conventional drugs have failed.
    American heart journal, 1975, Volume: 90, Issue:3

    Topics: Adult; Dose-Response Relationship, Drug; Drug Evaluation; Drug Therapy, Combination; Edema; Female;

1975
Current treatment of malignant hypertension.
    JAMA, 1975, Jun-30, Volume: 232, Issue:13

    Topics: Acute Disease; Administration, Oral; Antihypertensive Agents; Blood Pressure; Diazoxide; Diuretics;

1975
Patient with malignant hypertension alive after 25 years. A case report.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1986, Nov-22, Volume: 70, Issue:11

    Topics: Adult; Chlorothiazide; Drug Therapy, Combination; Follow-Up Studies; Guanethidine; Humans; Hydralazi

1986
[Hypertensive emergencies].
    Der Internist, 1974, Volume: 15, Issue:3

    Topics: Brain Edema; Clonidine; Diazoxide; Digitalis Glycosides; Diuretics; Drug Combinations; Emergencies;

1974
Hypertension.
    The Practitioner, 1974, Volume: 213, Issue:1276 SPEC

    Topics: Adrenergic beta-Antagonists; Aortic Diseases; Benzothiadiazines; Brain Diseases; Cerebrovascular Dis

1974
Management of renal hypertension complicated by renal insufficiency.
    Lancet (London, England), 1967, Oct-07, Volume: 2, Issue:7519

    Topics: Blood Urea Nitrogen; Chlorothiazide; Guanethidine; Humans; Hydralazine; Hypertension, Malignant; Met

1967
Malignant hypertension associated with oral contraceptives.
    Lancet (London, England), 1969, Aug-30, Volume: 2, Issue:7618

    Topics: Adult; Blood Pressure; Contraceptives, Oral; Female; Guanethidine; Guanidines; Humans; Hypertension,

1969
The need for early reduction of blood pressure: illustrated by the long-term results of treatment of hypertension.
    The New Zealand medical journal, 1968, Volume: 67, Issue:429

    Topics: Adolescent; Adult; Aged; Antihypertensive Agents; Benzothiadiazines; Diuretics; Female; Ganglionic B

1968
[Conservative treatment of hypertension].
    Munchener medizinische Wochenschrift (1950), 1970, Nov-20, Volume: 112, Issue:47

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Aniline Compounds; Dihydroxyphenylalanine; Female; Guaneth

1970
Dietary sodium restriction and natriuresis in management of hypertension.
    The Journal of the Egyptian Medical Association, 1974, Volume: 57, Issue:1-2

    Topics: Adult; Aged; Benzothiadiazines; Diet, Sodium-Restricted; Diuretics; Ethacrynic Acid; Female; Furosem

1974
Heparin therapy for the renal disease of malignant hypertension.
    Nephron, 1974, Volume: 12, Issue:3

    Topics: Adult; Anemia, Hemolytic; Creatinine; Dipyridamole; Female; Guanethidine; Hematoma; Heparin; Humans;

1974
Malignant hypertension in children; a patient treated with bilateral nephrectomy.
    American journal of diseases of children (1960), 1974, Volume: 128, Issue:6

    Topics: Blood Pressure; Child; Creatinine; Female; Guanethidine; Humans; Hydralazine; Hydrochlorothiazide; H

1974
Management of severe hypertension.
    Journal of the Irish Medical Association, 1972, Dec-09, Volume: 65, Issue:23

    Topics: Chlorthalidone; Coma; Debrisoquin; Diazoxide; Guanethidine; Humans; Hypertension, Malignant; Methyld

1972
Problems in therapy for the hypertensive patient.
    Geriatrics, 1973, Volume: 28, Issue:3

    Topics: Antihypertensive Agents; Blood Pressure; Carotid Sinus; Diuretics; Electric Stimulation; Ethacrynic

1973
Treatment of malignant hypertension with sodium nitroprusside.
    Archives of internal medicine, 1974, Volume: 133, Issue:2

    Topics: Administration, Oral; Adult; Aged; Blood Pressure; Chemical Phenomena; Chemistry; Diazoxide; Drug Re

1974
Management of malignant hypertension complicated by renal insufficiency. A follow-up study.
    The New England journal of medicine, 1974, Jul-04, Volume: 291, Issue:1

    Topics: Adult; Aged; Arteries; Autopsy; Benzothiadiazines; Diuretics; Drug Therapy, Combination; Female; Fol

1974
Malignant hypertension treated with modern antihypertensive drugs.
    Pennsylvania medicine, 1974, Volume: 77, Issue:7

    Topics: Antihypertensive Agents; Blood Urea Nitrogen; Creatinine; Diuretics; Female; Guanethidine; Humans; H

1974
[Respective roles of hemodynamic or humoral factors and of hypotensive or salidiuretic drugs in the development of essential hypertension].
    Pathologie et biologie, 1965, Volume: 13, Issue:21

    Topics: Adult; Chlorthalidone; Diet, Sodium-Restricted; Electrocardiography; Guanethidine; Humans; Hydrochlo

1965
[What is reliable in the therapy of hypertension?].
    Der Internist, 1970, Volume: 11, Issue:12

    Topics: Arteriosclerosis; Cerebral Hemorrhage; Diet, Reducing; Diet, Sodium-Restricted; Guanethidine; Health

1970
Malignant hypertension: effect of therapy on renin and aldosterone.
    Circulation research, 1971, Volume: 28, Issue:5

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adult; Aldosterone; Antihypertensive Agents; Blood

1971
[Intramuscular guanethidine in the treatment of hypertensive crises and malignant arterial hypertension].
    La Clinica terapeutica, 1967, Dec-15, Volume: 43, Issue:5

    Topics: Adult; Aged; Arteries; Female; Guanethidine; Humans; Hypertension; Hypertension, Malignant; Injectio

1967
[The medicamentous management of acute hypertonic crisis].
    Wiener klinische Wochenschrift, 1968, Feb-16, Volume: 80, Issue:7

    Topics: Acute Disease; Blood Pressure; Cardiac Output; Guanethidine; Humans; Hypertension, Malignant; Inject

1968
Fourteen-year survival in a case of malignant hypertension under hypotensive drug therapy.
    Canadian Medical Association journal, 1968, Nov-30, Volume: 99, Issue:21

    Topics: Adult; Antihypertensive Agents; Chlorothiazide; Guanethidine; Hexamethonium Compounds; Humans; Hydra

1968
[Considerations on ambulatory therapy in a group of hypertensive patients].
    Minerva medica, 1969, Jun-27, Volume: 60, Issue:51

    Topics: Adult; Aged; Ambulatory Care; Carbamates; Female; Guanethidine; Humans; Hydralazine; Hydrochlorothia

1969
Clinical observations on the effects of debrisoquine sulphate in patients with high blood-pressure.
    British medical journal, 1966, Sep-24, Volume: 2, Issue:5516

    Topics: Adolescent; Adult; Aged; Amidines; Antihypertensive Agents; Female; Guanethidine; Humans; Hypertensi

1966