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guanethidine and Hemorrhage

guanethidine has been researched along with Hemorrhage in 13 studies

Guanethidine: An antihypertensive agent that acts by inhibiting selectively transmission in post-ganglionic adrenergic nerves. It is believed to act mainly by preventing the release of norepinephrine at nerve endings and causes depletion of norepinephrine in peripheral sympathetic nerve terminals as well as in tissues.
guanethidine : A member of the class of guanidines in which one of the hydrogens of the amino group has been replaced by a 2-azocan-1-ylethyl group.
guanethidine sulfate : A organic sulfate salt composed of two molecules of guanethidine and one of sulfuric acid.

Hemorrhage: Bleeding or escape of blood from a vessel.

Research Excerpts

ExcerptRelevanceReference
" (i) Sham-operated animals submitted to intravenous administration of [Sar(1),Thr(8)]-angiotensin II (sarthran), an angiotensin II antagonist (750 ng/100 g bw as a bolus plus an infusion of 25 ng/100 g bw/min over 30 min), which did not alter the prolactin secretion in response to hemorrhage."7.71Evidence of angiotensin II involvement in prolactin secretion in response to hemorrhage in adrenodemedullated and guanethidine-treated rats. ( Coimbra, CC; Machado, LJ; Reis, AM, 2002)
"The present experiments were designed to further investigate the action of an angiotensin II antagonist on the hyperglycemic response to hemorrhage (1."7.69Effect of [1-Sar,8-Thr]-angiotensin II on the hyperglycemic response to hemorrhage in adrenodemedullated and guanethidine-treated rats. ( Coimbra, CC; Machado, LJ; Marubayashi, U; Reis, AM, 1995)
"Naloxone (6 mg/kg) was injected intravenously."5.27Sympathoadrenal mechanisms in cardiovascular responses to naloxone after hemorrhage. ( Ludbrook, J; Potocnik, SJ; Rutter, PC, 1987)
" (i) Sham-operated animals submitted to intravenous administration of [Sar(1),Thr(8)]-angiotensin II (sarthran), an angiotensin II antagonist (750 ng/100 g bw as a bolus plus an infusion of 25 ng/100 g bw/min over 30 min), which did not alter the prolactin secretion in response to hemorrhage."3.71Evidence of angiotensin II involvement in prolactin secretion in response to hemorrhage in adrenodemedullated and guanethidine-treated rats. ( Coimbra, CC; Machado, LJ; Reis, AM, 2002)
"The present experiments were designed to further investigate the action of an angiotensin II antagonist on the hyperglycemic response to hemorrhage (1."3.69Effect of [1-Sar,8-Thr]-angiotensin II on the hyperglycemic response to hemorrhage in adrenodemedullated and guanethidine-treated rats. ( Coimbra, CC; Machado, LJ; Marubayashi, U; Reis, AM, 1995)
" Pretreatment with guanethidine did not affect basal output of HCO3- but markedly reduced the bleeding-induced response."3.67Bleeding-induced decrease in duodenal HCO3- secretion in the rat is mediated via alpha 2-adrenoceptors. ( Fändriks, L; Jönson, C, 1987)
"Naloxone (6 mg/kg) was injected intravenously."1.27Sympathoadrenal mechanisms in cardiovascular responses to naloxone after hemorrhage. ( Ludbrook, J; Potocnik, SJ; Rutter, PC, 1987)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-199010 (76.92)18.7374
1990's2 (15.38)18.2507
2000's1 (7.69)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
MCGIFF, JC1
Chalmers, JP1
Korner, PI1
White, SW1
Kinoshita, Y1
Monafo, WW1
Machado, LJ2
Marubayashi, U1
Reis, AM2
Coimbra, CC2
Wijnen, HJ1
De Kloet, ER1
Versteeg, DH1
De Jong, W1
Powers, JC1
Shaftan, GW1
Herbsman, H1
Jönson, C1
Fändriks, L1
Rutter, PC1
Potocnik, SJ1
Ludbrook, J1
Demailly, P1
Story, ME1
Bentley, GA1
Osterholm, JL1
Mathews, GJ1
Irvin, JD1
Calesnick, B1
Subbu, VS1

Reviews

1 review available for guanethidine and Hemorrhage

ArticleYear
[Glaucoma].
    Archives d'ophtalmologie et revue generale d'ophtalmologie, 1968, Volume: 28, Issue:2

    Topics: Acetazolamide; Angiography; Aqueous Humor; Cataract; Cholinesterase Inhibitors; Chronic Disease; Dex

1968

Other Studies

12 other studies available for guanethidine and Hemorrhage

ArticleYear
THE RENAL VASCULAR RESPONSE TO HEMORRHAGE.
    The Journal of pharmacology and experimental therapeutics, 1964, Volume: 145

    Topics: Adrenalectomy; Animals; Autonomic Nervous System; Blood Circulation; Denervation; Dogs; Guanethidine

1964
The effects of haemorrhage in the unanaesthetized rabbit.
    The Journal of physiology, 1967, Volume: 189, Issue:3

    Topics: Adrenal Glands; Adrenal Medulla; Adrenalectomy; Animals; Autonomic Nervous System; Blood Circulation

1967
Guanethidine chemical sympathectomy: spinal cord and sciatic nerve blood flow.
    The American journal of physiology, 1993, Volume: 265, Issue:4 Pt 2

    Topics: Animals; Brachial Plexus; Catecholamines; Guanethidine; Hemodynamics; Hemorrhage; Male; Posture; Rat

1993
Effect of [1-Sar,8-Thr]-angiotensin II on the hyperglycemic response to hemorrhage in adrenodemedullated and guanethidine-treated rats.
    Regulatory peptides, 1995, Dec-07, Volume: 60, Issue:1

    Topics: Adrenal Medulla; Adrenergic Antagonists; Angiotensin II; Animals; Blood Glucose; Guanethidine; Hemor

1995
Evidence of angiotensin II involvement in prolactin secretion in response to hemorrhage in adrenodemedullated and guanethidine-treated rats.
    European journal of endocrinology, 2002, Volume: 146, Issue:3

    Topics: Adrenal Medulla; Adrenalectomy; Angiotensin II; Animals; Guanethidine; Hemorrhage; Male; Prolactin;

2002
Differences in regional brain catecholamine metabolism after a decrease in blood pressure.
    Life sciences, 1978, Dec-25, Volume: 23, Issue:26

    Topics: Animals; Blood Pressure; Brain; Catecholamines; Dopamine; Epinephrine; Guanethidine; Hemorrhage; Mal

1978
Evaluation of various hypotensive agents in the control of experimental hemorrhage.
    The Journal of surgical research, 1975, Volume: 18, Issue:1

    Topics: Animals; Antihypertensive Agents; Blood Pressure; Chlorpromazine; Diazoxide; Dogs; Drug Evaluation,

1975
Bleeding-induced decrease in duodenal HCO3- secretion in the rat is mediated via alpha 2-adrenoceptors.
    Acta physiologica Scandinavica, 1987, Volume: 130, Issue:3

    Topics: Animals; Bicarbonates; Duodenum; Guanethidine; Hemorrhage; Male; Prazosin; Propranolol; Rats; Rats,

1987
Sympathoadrenal mechanisms in cardiovascular responses to naloxone after hemorrhage.
    The American journal of physiology, 1987, Volume: 252, Issue:1 Pt 2

    Topics: Adrenal Medulla; Adrenalectomy; Animals; Blood Pressure; Cardiovascular Physiological Phenomena; Car

1987
The effects of drugs and treatments upon adrenaline re-reversal in the rabbit.
    Archives internationales de pharmacodynamie et de therapie, 1974, Volume: 212, Issue:1

    Topics: Animals; Blood Pressure; Bretylium Compounds; Cocaine; Diphenhydramine; Ear; Epinephrine; Female; Gu

1974
Chapter 29. Anti-norepinephrine therapy against traumatic hemorrhagic necrosis of the spinal cord: preliminary report.
    Clinical neurosurgery, 1973, Volume: 20

    Topics: Animals; Bretylium Compounds; Cats; Dihydroxyphenylalanine; Disease Models, Animal; Disulfiram; Guan

1973
The influence of guanethidine pretreatment upon the haemodynamics of dogs under haemorrhagic hypotension.
    The Indian journal of medical research, 1971, Volume: 59, Issue:7

    Topics: Animals; Dogs; Guanethidine; Hemodynamics; Hemorrhage; Hypotension; Premedication

1971