guanethidine and Flaccid Quadriplegia studies

guanethidine and Flaccid Quadriplegia

Guanethidine: An antihypertensive agent that acts by inhibiting selectively transmission in post-ganglionic adrenergic nerves. It is believed to act mainly by preventing the release of norepinephrine at nerve endings and causes depletion of norepinephrine in peripheral sympathetic nerve terminals as well as in tissues.
guanethidine : A member of the class of guanidines in which one of the hydrogens of the amino group has been replaced by a 2-azocan-1-ylethyl group.
guanethidine sulfate : A organic sulfate salt composed of two molecules of guanethidine and one of sulfuric acid.

Research Excerpts

Excerpt	Relevance	Reference
"During hyperreflexia the pre-ejection period/left ventricular ejection time (PEP/LVET) ratio and the PEP and electromechanical systole (QS2) reduced, suggesting positive inotropic effects."	1.26	Sympathetic hyperreflexia in tetraplegics. The value of systolic time intervals in assessing drug effects. ( Sommers, DK, 1980)

Research

Studies (4)

Timeframe	Studies, this research(%)	All Research%
pre-1990	4 (100.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Timeframe

Studies, this research(%)

All Research%

pre-1990

4 (100.00)

18.7374

1990's

0 (0.00)

18.2507

2000's

0 (0.00)

29.6817

2010's

0 (0.00)

24.3611

2020's

0 (0.00)

2.80

Authors

Authors	Studies
Sommers, DK	2
Unwin, RJ	1
Mathias, CJ	1
Peart, WS	1
Frankel, HL	1
Shea, JD	1
Gioffre, R	1
Carrion, H	1
Small, MP	1

Studies

Sommers, DK

Unwin, RJ

Mathias, CJ

Peart, WS

Frankel, HL

Shea, JD

Gioffre, R

Carrion, H

Small, MP

Other Studies

4 other studies available for guanethidine and Flaccid Quadriplegia

Article	Year
Sympathetic hyperreflexia in tetraplegics. The value of systolic time intervals in assessing drug effects. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1980, Dec-13, Volume: 58, Issue:24 Topics: Adult; Guanethidine; Humans; Hypertension; Labetalol; Male; Middle Aged; Myocardial Contraction; Phe	1980
Reactivity of the cardiovascular system in the tetraplegic patient. Clinical pharmacology and therapeutics, 1979, Volume: 26, Issue:3 Topics: Adrenergic beta-Antagonists; Atropine; Blood Pressure; Electrocardiography; Guanethidine; Heart Rate	1979
Renal vascular responses to saralasin in conscious chemically denervated rabbits and patients with tetraplegia. Clinical and experimental hypertension. Part A, Theory and practice, 1986, Volume: 8, Issue:6 Topics: Adult; Angiotensin II; Animals; Consciousness; Female; Glomerular Filtration Rate; Guanethidine; Hum	1986
Autonomic hyperreflexia in spinal cord injury. Southern medical journal, 1973, Volume: 66, Issue:8 Topics: Adult; Autonomic Nervous System; Blood Pressure; Bradycardia; Cervical Vertebrae; Electroencephalogr	1973

Article

Year

Sympathetic hyperreflexia in tetraplegics. The value of systolic time intervals in assessing drug effects.

South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1980, Dec-13, Volume: 58, Issue:24

Topics: Adult; Guanethidine; Humans; Hypertension; Labetalol; Male; Middle Aged; Myocardial Contraction; Phe

1980

Reactivity of the cardiovascular system in the tetraplegic patient.

Clinical pharmacology and therapeutics, 1979, Volume: 26, Issue:3

Topics: Adrenergic beta-Antagonists; Atropine; Blood Pressure; Electrocardiography; Guanethidine; Heart Rate

1979

Renal vascular responses to saralasin in conscious chemically denervated rabbits and patients with tetraplegia.

Clinical and experimental hypertension. Part A, Theory and practice, 1986, Volume: 8, Issue:6

Topics: Adult; Angiotensin II; Animals; Consciousness; Female; Glomerular Filtration Rate; Guanethidine; Hum

1986

Autonomic hyperreflexia in spinal cord injury.

Southern medical journal, 1973, Volume: 66, Issue:8

Topics: Adult; Autonomic Nervous System; Blood Pressure; Bradycardia; Cervical Vertebrae; Electroencephalogr

1973