Page last updated: 2024-10-28

guanethidine and Eye Diseases

guanethidine has been researched along with Eye Diseases in 16 studies

Guanethidine: An antihypertensive agent that acts by inhibiting selectively transmission in post-ganglionic adrenergic nerves. It is believed to act mainly by preventing the release of norepinephrine at nerve endings and causes depletion of norepinephrine in peripheral sympathetic nerve terminals as well as in tissues.
guanethidine : A member of the class of guanidines in which one of the hydrogens of the amino group has been replaced by a 2-azocan-1-ylethyl group.
guanethidine sulfate : A organic sulfate salt composed of two molecules of guanethidine and one of sulfuric acid.

Eye Diseases: Diseases affecting the eye.

Research Excerpts

ExcerptRelevanceReference
"1% noradrenaline or 10% phenylepherine to either a surgically sympathectomised or a guanethidine treated rabbit eye induced a transient increase in intraocular pressure (IOP), between 90 and 150 min, followed by a fall to hypotensive levels."3.66Prostaglandin mediated inflammatory changes induced by alpha-adrenoceptor stimulation in the sympathectomised rabbit eye. ( Unger, WG, 1979)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-199016 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
BONOMI, L2
DI COMITE, P1
UENO, K1
TUJI, K1
FUKUDA, H1
DIOTALLEVI, M1
TIBERI, GF1
PANNARALE, C1
RAGNETTI, E1
OOSTERHUIS, JA1
Unger, WG1
Pasik, T1
Pasik, P1
Freis, ED1
Crombie, AL1
Lawson, AA1
Aviner, Z1
Bonnet, M1
Lemarchands, H1
Martin, J1
Skinner, SW1
Miller, JE1
Sneddon, JM1
Turner, P1
Gay, AJ1
Wolkstein, MA1

Reviews

1 review available for guanethidine and Eye Diseases

ArticleYear
Effectiveness of drug therapy in hypertension: present status. A review.
    Circulation research, 1971, Volume: 28, Issue:5

    Topics: Antihypertensive Agents; Cerebrovascular Disorders; Coronary Disease; Eye Diseases; Ganglionic Block

1971

Trials

1 trial available for guanethidine and Eye Diseases

ArticleYear
Adrenergic blocking agents. A double-blind trial in the treatment of the eye signs of thyroid disorders.
    The British journal of ophthalmology, 1968, Volume: 52, Issue:8

    Topics: Antihypertensive Agents; Bretylium Compounds; Clinical Trials as Topic; Edema; Exophthalmos; Eye Dis

1968

Other Studies

14 other studies available for guanethidine and Eye Diseases

ArticleYear
[Action of guanethidine on intraocular pressure].
    Annali di ottalmologia e clinica oculistica, 1963, Volume: 89

    Topics: Eye Diseases; Glaucoma; Guanethidine; Intraocular Pressure; Tetrahymenina; Tonometry, Ocular

1963
[Trial use of a drug to reduce intraocular pressure, 10 per cent Ismelin, as eye drops].
    Rinsho ganka. Japanese journal of clinical ophthalmology, 1963, Volume: 17

    Topics: Eye Diseases; Glaucoma; Guanethidine; Humans; Intraocular Pressure; Ophthalmic Solutions; Tetrahymen

1963
[EFFECTS OF GUANETHIDINE ON OCULAR FLUID DYNAMICS].
    Annali di ottalmologia e clinica oculistica, 1963, Volume: 89

    Topics: Eye; Eye Diseases; Glaucoma; Guanethidine; Humans; Hydrodynamics; Intraocular Pressure; Tonometry, O

1963
[ON THE EFFECTS OF THE ASSOCIATION OF PILOCARPINE AND GUANETHIDINE INTRAOCULAR TENSION].
    Bollettino d'oculistica, 1963, Volume: 42

    Topics: Eye Diseases; Glaucoma; Guanethidine; Humans; Hydrophthalmos; Intraocular Pressure; Pharmacology; Pi

1963
[ON ACTION OF INSTILLATION OF GUANETHIDINE ON EXPERIMENTAL OCULAR HYPERTENSION IN THE RABBIT].
    Bollettino d'oculistica, 1964, Volume: 43

    Topics: Animals; Eye Diseases; Guanethidine; Intraocular Pressure; Lagomorpha; Ocular Hypertension; Pharmaco

1964
Guanethidine (Ismelin) in ophthalmology. I. Observations in rabbits.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1962, Volume: 67

    Topics: Amidines; Animals; Eye Diseases; Guanethidine; Intraocular Pressure; Ophthalmology; Pupil; Rabbits;

1962
Prostaglandin mediated inflammatory changes induced by alpha-adrenoceptor stimulation in the sympathectomised rabbit eye.
    Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie. Albrecht von Graefe's archive for clinical and experimental ophthalmology, 1979, Volume: 211, Issue:4

    Topics: Animals; Epinephrine; Eye; Eye Diseases; Female; Guanethidine; Indomethacin; Intraocular Pressure; M

1979
Experimental models of oculomotor dysfunction in the rhesus monkey.
    Advances in neurology, 1975, Volume: 10

    Topics: Adrenergic alpha-Antagonists; Animals; Corpus Callosum; Disease Models, Animal; Eye Diseases; Eye Mo

1975
Pupil-block. Its mechanism and prevention. II. Dilating the pupil by a mydriaticum-ismelin combination. A procedure with minimal risk.
    Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde, 1971, Volume: 163, Issue:4

    Topics: Dilatation; Eye Diseases; Glaucoma; Guanethidine; Humans; Intraocular Pressure; Mydriatics; Pupil; S

1971
Guanethidine eyedrops.
    Drug and therapeutics bulletin, 1969, Oct-10, Volume: 7, Issue:21

    Topics: Eye Diseases; Guanethidine; Humans; Ophthalmic Solutions

1969
[Prevention and treatment of the "irreducible mydriasis--progressive atrophy of the iris" syndrome following perforating keratoplasty for keratoconus].
    Annales d'oculistique, 1969, Volume: 202, Issue:11

    Topics: Acetylcholine; Anesthetics, Local; Atrophy; Atropine; Eye Diseases; Eye Injuries; Guanethidine; Huma

1969
Permanent improvement of thyroid-related upper eyelid retraction from bethanidine.
    American journal of ophthalmology, 1969, Volume: 67, Issue:5

    Topics: Antihypertensive Agents; Cornea; Eye Diseases; Eyelids; Follow-Up Studies; Guanethidine; Guanidines;

1969
The interactions of local guanethidine and sympathomimetic amines in the human eye.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1969, Volume: 81, Issue:5

    Topics: Amphetamine; Drug Synergism; Ephedrine; Epinephrine; Eye Diseases; Eyelids; Guanethidine; Humans; Hy

1969
Topical guanethidine therapy for endocrine lid retraction.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1966, Volume: 76, Issue:3

    Topics: Eye Diseases; Eyelids; Graves Disease; Guanethidine; Humans

1966