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guanethidine and Edema

guanethidine has been researched along with Edema in 28 studies

Guanethidine: An antihypertensive agent that acts by inhibiting selectively transmission in post-ganglionic adrenergic nerves. It is believed to act mainly by preventing the release of norepinephrine at nerve endings and causes depletion of norepinephrine in peripheral sympathetic nerve terminals as well as in tissues.
guanethidine : A member of the class of guanidines in which one of the hydrogens of the amino group has been replaced by a 2-azocan-1-ylethyl group.
guanethidine sulfate : A organic sulfate salt composed of two molecules of guanethidine and one of sulfuric acid.

Edema: Abnormal fluid accumulation in TISSUES or body cavities. Most cases of edema are present under the SKIN in SUBCUTANEOUS TISSUE.

Research Excerpts

ExcerptRelevanceReference
"Twenty-six patients were selected for treatment with minoxidil on the basis of hypertension which could not be controlled either because of (1) drug failures and/or (2) side effects of drugs."7.65Minoxidil in severe hypertension: value when conventional drugs have failed. ( Dormois, JC; Nies, AS; Young, JL, 1975)
" Propranolol and diuretics were given to prevent reflex tachycardia and fluid retention."7.65Severe hypertension. Treatment with minoxidil. ( Dunea, G; Mahurkar, SD; Mamdani, B; Mehta, PK; Shansky, RM, 1975)
"Rats with chemical sympathectomy, induced either at neonatal age (long-term sympathectomy) or in adult animals (short-term sympathectomy) by guanethidine or by 6-hydroxydopamine, were used to determine the contribution of sympathetic noradrenergic fibres to afferent neuron-mediated responses and to non-neurogenic inflammation in the rat."3.68Neurogenic and non-neurogenic inflammation in the rat paw following chemical sympathectomy. ( Amann, R; Donnerer, J; Lembeck, F, 1991)
"Twenty-six patients were selected for treatment with minoxidil on the basis of hypertension which could not be controlled either because of (1) drug failures and/or (2) side effects of drugs."3.65Minoxidil in severe hypertension: value when conventional drugs have failed. ( Dormois, JC; Nies, AS; Young, JL, 1975)
" Propranolol and diuretics were given to prevent reflex tachycardia and fluid retention."3.65Severe hypertension. Treatment with minoxidil. ( Dunea, G; Mahurkar, SD; Mamdani, B; Mehta, PK; Shansky, RM, 1975)
"Loratadine pretreatment, but neither guanethidine nor indomethacin, reduced edema."1.32Nociceptive and edematogenic responses elicited by a crude bristle extract of Lonomia obliqua caterpillars. ( de Castro Bastos, L; GuimarĂ£es, JA; Tonussi, CR; Veiga, AB, 2004)

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-199025 (89.29)18.7374
1990's2 (7.14)18.2507
2000's1 (3.57)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
RONNOV-JESSEN, V1
BARTTER, FC2
URANGAIMAZ, FA1
TONNELIER, E1
KLAUER, D1
CHEKHERDEMIAN, M1
LECOMTE, J1
CESSION-FOSSION, A1
LIBON, JC1
BACQ, ZM1
VASKO, JS1
BROCKMAN, SK1
GILL, JR1
MASON, DT1
SMITH, AJ2
de Castro Bastos, L1
Veiga, AB1
GuimarĂ£es, JA1
Tonussi, CR1
Crombie, AL2
Lawson, AA2
Aarts, HF1
Procacci, P1
Zoppi, M1
Maresca, M1
Dormois, JC1
Young, JL1
Nies, AS1
Mehta, PK1
Mamdani, B1
Shansky, RM1
Mahurkar, SD1
Dunea, G1
Donnerer, J1
Amann, R1
Lembeck, F1
Cunha, FQ1
Lorenzetti, BB1
Poole, S1
Ferreira, SH1
Atkinson, DC1
Hicks, R1
Arntzen, FC1
Briseid, K1
Damas, J1
Lallemand, G1
Barnea, A1
Martin, JD1
Clark, DW1
Goldberg, LI1
Haller, J1
Haddad, HM1
Caprino, L1
Borrelli, F1
Falchetti, R1
Vertes, V1
Cangiano, JL1
Berman, LB1
Gould, A1

Trials

2 trials available for guanethidine and Edema

ArticleYear
Guancydine: a new antihypertensive agent. Use with quinethazone and guanethidine or propranolol.
    Annals of internal medicine, 1972, Volume: 76, Issue:4

    Topics: Antihypertensive Agents; Anxiety; Aspartate Aminotransferases; Blood Pressure; Clinical Trials as To

1972
Adrenergic blocking agents. A double-blind trial in the treatment of the eye signs of thyroid disorders.
    The British journal of ophthalmology, 1968, Volume: 52, Issue:8

    Topics: Antihypertensive Agents; Bretylium Compounds; Clinical Trials as Topic; Edema; Exophthalmos; Eye Dis

1968

Other Studies

26 other studies available for guanethidine and Edema

ArticleYear
BLOOD-VOLUME DURING TREATMENT OF HYPERTENSION WITH GUANETHIDINE.
    Acta medica Scandinavica, 1963, Volume: 174

    Topics: Blood Pressure Determination; Blood Volume; Blood Volume Determination; Edema; Guanethidine; Hyperte

1963
CARDIAC FAILURE AND HORMONAL CONTROL OF FLUID AND ELECTROLYTE BALANCE.
    Surgery, gynecology & obstetrics, 1964, Volume: 118

    Topics: Aldosterone; Angiotensins; Catecholamines; Corticosterone; Cortisone; Edema; Guanethidine; Heart Fai

1964
[DIURETIC DRUGS IN THE EDEMAS OF PREGNANCY].
    Revista de la Asociacion Medica Argentina, 1964, Volume: 78

    Topics: Acetazolamide; Benzothiadiazines; Blood Pressure; Body Weight; Chlorothiazide; Diuretics; Edema; Fem

1964
[ON SOME GENERAL PHARMACODYNAMIC EFFECTS OF CYSTAMINE IN THE RAT].
    Archives internationales de pharmacodynamie et de therapie, 1964, Apr-01, Volume: 148

    Topics: Adrenalectomy; Anti-Allergic Agents; Antihypertensive Agents; Bis-Trimethylammonium Compounds; Blood

1964
MASSIVE VENOUS OCCLUSION OF THE LOWER EXTREMITY.
    Surgical forum, 1964, Volume: 15

    Topics: Animals; Blood Transfusion; Cyanosis; Dogs; Edema; Gangrene; Guanethidine; Iliac Vein; Lower Extremi

1964
"IDIOPATHIC" EDEMA RESULTING FROM OCCULT CARDIOMYOPATHY.
    The American journal of medicine, 1965, Volume: 38

    Topics: Cardiac Catheterization; Cardiomyopathies; Desoxycorticosterone; Diagnosis; Digoxin; Drug Therapy; E

1965
CLINICAL FEATURES OF FLUID RETENTION COMPLICATING TREATMENT WITH GUANETHIDINE.
    Circulation, 1965, Volume: 31

    Topics: Body Weight; Drug Therapy; Edema; Electrocardiography; Female; Geriatrics; Guanethidine; Hypertensio

1965
FLUID RETENTION PRODUCED BY GUANETHIDINE; CHANGES IN BODY EXCHANGEABLE SODIUM, BLOOD VOLUME, AND CREATININE CLEARANCE.
    Circulation, 1965, Volume: 31

    Topics: Blood; Blood Volume; Body Weight; Creatine; Creatinine; Drug Therapy; Edema; Guanethidine; Humans; H

1965
Nociceptive and edematogenic responses elicited by a crude bristle extract of Lonomia obliqua caterpillars.
    Toxicon : official journal of the International Society on Toxinology, 2004, Mar-01, Volume: 43, Issue:3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthropod Venoms; Dose-Response Relationship, Drug

2004
Long-term trial of local guanethidine in treatment of eye signs of thyroid dysfunction and idiopathic lid retraction.
    British medical journal, 1967, Dec-09, Volume: 4, Issue:5579

    Topics: Edema; Exophthalmos; Eye Manifestations; Eyelids; Female; Guanethidine; Humans; Hyperthyroidism; Hyp

1967
Regional intravascular sympathetic blockade for better results in flap surgery: an experimental study of free flaps, island flaps, and pedicle flaps in the rabbit ear.
    Plastic and reconstructive surgery, 1980, Volume: 66, Issue:5

    Topics: Animals; Autonomic Nerve Block; Ear, External; Edema; Female; Follow-Up Studies; Graft Survival; Gua

1980
[Guanethidine therapy of reflex sympathetic syndromes].
    La Clinica terapeutica, 1975, Jun-30, Volume: 73, Issue:6

    Topics: Adult; Aged; Arterial Occlusive Diseases; Causalgia; Drug Evaluation; Edema; Female; Fibromyalgia; G

1975
Minoxidil in severe hypertension: value when conventional drugs have failed.
    American heart journal, 1975, Volume: 90, Issue:3

    Topics: Adult; Dose-Response Relationship, Drug; Drug Evaluation; Drug Therapy, Combination; Edema; Female;

1975
Severe hypertension. Treatment with minoxidil.
    JAMA, 1975, Jul-21, Volume: 233, Issue:3

    Topics: Adult; Black People; Drug Evaluation; Edema; Female; Follow-Up Studies; Guanethidine; Humans; Hypert

1975
Neurogenic and non-neurogenic inflammation in the rat paw following chemical sympathectomy.
    Neuroscience, 1991, Volume: 45, Issue:3

    Topics: Afferent Pathways; Animals; Calcitonin Gene-Related Peptide; Carrageenan; Edema; Foot; Guanethidine;

1991
Interleukin-8 as a mediator of sympathetic pain.
    British journal of pharmacology, 1991, Volume: 104, Issue:3

    Topics: Animals; Atenolol; Benzazepines; Carrageenan; Dinoprostone; Edema; Foot; Guanethidine; Interleukin-1

1991
Editorial: The eye signs of Graves disease.
    Lancet (London, England), 1974, Mar-23, Volume: 1, Issue:7856

    Topics: Edema; Exophthalmos; Eye; Eye Manifestations; Female; Graves Disease; Guanethidine; Humans; Male; Mu

1974
Possible role of adrenergic mechanisms in the systemic anti-inflammatory activity of acetic acid in rats.
    European journal of pharmacology, 1974, Volume: 26, Issue:2

    Topics: Acetates; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Anti-Inflammatory Agen

1974
Inhibition of carrageenin-induced rat paw oedema by catecholamines and amine-depleting drugs.
    Acta pharmacologica et toxicologica, 1973, Volume: 32, Issue:3

    Topics: Animals; Carrageenan; Catecholamines; Edema; Epinephrine; Female; Fibrinolysin; Guanethidine; Iproni

1973
[Pyridinolcarbamate and bradykinin in the rat].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1974, Volume: 168, Issue:2-3

    Topics: Adrenal Glands; Animals; Blood Pressure; Bradykinin; Capillary Permeability; Carbamates; Dextrans; D

1974
Effect of sympathetic blocking agents on the uterine response to estrogen.
    Endocrinology, 1969, Volume: 84, Issue:4

    Topics: Adrenal Medulla; Adrenalectomy; Age Factors; Animals; Carbon Isotopes; Castration; Depression, Chemi

1969
The management of hypertensive disease of pregnancy.
    Drugs, 1974, Volume: 8, Issue:2

    Topics: Blood Pressure; Diazoxide; Eclampsia; Edema; Estrogens; Female; Guanethidine; Humans; Hypertension;

1974
[Therapy of EPH gestosis].
    Deutsche medizinische Wochenschrift (1946), 1973, Jul-06, Volume: 98, Issue:27

    Topics: Chlorthalidone; Diazepam; Diet Therapy; Eclampsia; Edema; Female; Furosemide; Guanethidine; Humans;

1973
Pathogenesis and treatment of endocrine exophthalmos.
    International surgery, 1973, Volume: 58, Issue:7

    Topics: Blepharoptosis; Dexamethasone; Diplopia; Edema; Exophthalmos; Eye Neoplasms; Glaucoma; Graves Diseas

1973
Pharmacological research on 4,5-diphenyl-2-bis(2-hydroxyethyl)-aminoxazol (Ditazol), a new synthetic oxazole derivative as an anti-inflammatory agent.
    Arzneimittel-Forschung, 1973, Volume: 23, Issue:9

    Topics: Administration, Oral; Administration, Topical; Adrenalectomy; Analgesics; Animals; Anti-Inflammatory

1973
Hypertension in end-stage renal disease.
    The New England journal of medicine, 1969, May-01, Volume: 280, Issue:18

    Topics: Adolescent; Adult; Aged; Antihypertensive Agents; Black People; Blood Pressure; Body Weight; Chronic

1969