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guanethidine and Diabetic Neuropathies

guanethidine has been researched along with Diabetic Neuropathies in 2 studies

Guanethidine: An antihypertensive agent that acts by inhibiting selectively transmission in post-ganglionic adrenergic nerves. It is believed to act mainly by preventing the release of norepinephrine at nerve endings and causes depletion of norepinephrine in peripheral sympathetic nerve terminals as well as in tissues.
guanethidine : A member of the class of guanidines in which one of the hydrogens of the amino group has been replaced by a 2-azocan-1-ylethyl group.
guanethidine sulfate : A organic sulfate salt composed of two molecules of guanethidine and one of sulfuric acid.

Diabetic Neuropathies: Peripheral, autonomic, and cranial nerve disorders that are associated with DIABETES MELLITUS. These conditions usually result from diabetic microvascular injury involving small blood vessels that supply nerves (VASA NERVORUM). Relatively common conditions which may be associated with diabetic neuropathy include third nerve palsy (see OCULOMOTOR NERVE DISEASES); MONONEUROPATHY; mononeuropathy multiplex; diabetic amyotrophy; a painful POLYNEUROPATHY; autonomic neuropathy; and thoracoabdominal neuropathy. (From Adams et al., Principles of Neurology, 6th ed, p1325)

Research Excerpts

ExcerptRelevanceReference
"The effect of streptozotocin diabetes of 4-week duration on the adrenergic motor transmission and on the nonadrenergic, noncholinergic, inhibitory transmission in the rat anococcygeus was investigated by recording contractile and relaxant activity of isolated muscle preparations taken from diabetic and age-matched control animals."1.28Effect of streptozotocin diabetes on motor and inhibitory transmission in rat anococcygeus. ( Luheshi, GN; Zar, MA, 1992)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Luheshi, GN1
Zar, MA1
Zochodne, DW1
Ho, LT1

Other Studies

2 other studies available for guanethidine and Diabetic Neuropathies

ArticleYear
Effect of streptozotocin diabetes on motor and inhibitory transmission in rat anococcygeus.
    Canadian journal of physiology and pharmacology, 1992, Volume: 70, Issue:10

    Topics: Aldehyde Reductase; Animals; Autonomic Nervous System Diseases; Diabetes Mellitus, Experimental; Dia

1992
The influence of indomethacin and guanethidine on experimental streptozotocin diabetic neuropathy.
    The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 1992, Volume: 19, Issue:4

    Topics: Animals; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Guanethidine; Indomethacin; Male; N

1992