guanethidine has been researched along with Constipation in 2 studies
Guanethidine: An antihypertensive agent that acts by inhibiting selectively transmission in post-ganglionic adrenergic nerves. It is believed to act mainly by preventing the release of norepinephrine at nerve endings and causes depletion of norepinephrine in peripheral sympathetic nerve terminals as well as in tissues.
guanethidine : A member of the class of guanidines in which one of the hydrogens of the amino group has been replaced by a 2-azocan-1-ylethyl group.
guanethidine sulfate : A organic sulfate salt composed of two molecules of guanethidine and one of sulfuric acid.
Constipation: Infrequent or difficult evacuation of FECES. These symptoms are associated with a variety of causes, including low DIETARY FIBER intake, emotional or nervous disturbances, systemic and structural disorders, drug-induced aggravation, and infections.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Guanethidine at 3 mg/kg iv was able to partially block the effects." | 1.42 | Inhibitory Effects and Sympathetic Mechanisms of Distension in the Distal Organs on Small Bowel Motility and Slow Waves in Canine. ( Chen, JD; Song, J; Yin, J, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Song, J | 1 |
| Yin, J | 1 |
| Chen, JD | 1 |
| Mitolo-Chieppa, D | 1 |
| Mansi, G | 1 |
| Rinaldi, R | 1 |
| Montagnani, M | 1 |
| Potenza, MA | 1 |
| Genualdo, M | 1 |
| Serio, M | 1 |
| Mitolo, CI | 1 |
| Rinaldi, M | 1 |
| Altomare, DF | 1 |
| Memeo, V | 1 |
2 other studies available for guanethidine and Constipation
| Article | Year |
|---|---|
Inhibitory Effects and Sympathetic Mechanisms of Distension in the Distal Organs on Small Bowel Motility and Slow Waves in Canine.
Topics: Adrenergic Agents; Animals; Constipation; Dogs; Female; Gastrointestinal Motility; Guanethidine; Int | 2015 |
Cholinergic stimulation and nonadrenergic, noncholinergic relaxation of human colonic circular muscle in idiopathic chronic constipation.
Topics: Acetylcholine; Adenosine Triphosphate; Adult; Atropine; Cholinergic Fibers; Chronic Disease; Colon; | 1998 |