guanethidine has been researched along with Complex Regional Pain Syndromes in 5 studies
Guanethidine: An antihypertensive agent that acts by inhibiting selectively transmission in post-ganglionic adrenergic nerves. It is believed to act mainly by preventing the release of norepinephrine at nerve endings and causes depletion of norepinephrine in peripheral sympathetic nerve terminals as well as in tissues.
guanethidine : A member of the class of guanidines in which one of the hydrogens of the amino group has been replaced by a 2-azocan-1-ylethyl group.
guanethidine sulfate : A organic sulfate salt composed of two molecules of guanethidine and one of sulfuric acid.
Complex Regional Pain Syndromes: Conditions characterized by pain involving an extremity or other body region, HYPERESTHESIA, and localized autonomic dysfunction following injury to soft tissue or nerve. The pain is usually associated with ERYTHEMA; SKIN TEMPERATURE changes, abnormal sudomotor activity (i.e., changes in sweating due to altered sympathetic innervation) or edema. The degree of pain and other manifestations is out of proportion to that expected from the inciting event. Two subtypes of this condition have been described: type I; (REFLEX SYMPATHETIC DYSTROPHY) and type II; (CAUSALGIA). (From Pain 1995 Oct;63(1):127-33)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aim of this study was to evaluate the efficacy of guanethidine and lidocaine in the treatment of complex regional pain syndrome (CRPS) type I of the hand." | 9.12 | Treatment of complex regional pain syndrome type I of the hand with a series of intravenous regional sympathetic blocks with guanethidine and lidocaine. ( Briana, DD; Michaloglou, AA; Paraskevas, KI; Samara, M, 2006) |
| "The aim of this study was to evaluate the efficacy of guanethidine and lidocaine in the treatment of complex regional pain syndrome (CRPS) type I of the hand." | 5.12 | Treatment of complex regional pain syndrome type I of the hand with a series of intravenous regional sympathetic blocks with guanethidine and lidocaine. ( Briana, DD; Michaloglou, AA; Paraskevas, KI; Samara, M, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (60.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| O'Connell, NE | 1 |
| Wand, BM | 1 |
| McAuley, J | 1 |
| Marston, L | 1 |
| Moseley, GL | 1 |
| Kennedy, R | 1 |
| Hester, J | 1 |
| Simon, DW | 1 |
| Nordmann, GR | 1 |
| Lauder, GR | 1 |
| Grier, DJ | 1 |
| Paraskevas, KI | 2 |
| Michaloglou, AA | 1 |
| Briana, DD | 1 |
| Samara, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Infrared (FLIR) Imaging as a Monitor for Sympathetic Blocks in Complex Regional Pain Syndrome (CRPS)[NCT05693337] | 30 participants (Actual) | Observational | 2023-01-09 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for guanethidine and Complex Regional Pain Syndromes
| Article | Year |
|---|---|
Interventions for treating pain and disability in adults with complex regional pain syndrome.
Topics: Adult; Analgesics; Calcitonin; Complex Regional Pain Syndromes; Diphosphonates; Disabled Persons; Gu | 2013 |
1 trial available for guanethidine and Complex Regional Pain Syndromes
| Article | Year |
|---|---|
Treatment of complex regional pain syndrome type I of the hand with a series of intravenous regional sympathetic blocks with guanethidine and lidocaine.
Topics: Adult; Aged; Anesthetics, Local; Autonomic Nerve Block; Complex Regional Pain Syndromes; Drug Therap | 2006 |
3 other studies available for guanethidine and Complex Regional Pain Syndromes
| Article | Year |
|---|---|
Malignancy as a possible complication of complex regional pain syndrome: a case report.
Topics: Adult; Amputation, Surgical; Arthralgia; Bone Neoplasms; Complex Regional Pain Syndromes; Drug Resis | 2010 |
Computed tomography guided lumbar sympathetic block for complex regional pain syndrome in a child: a case report and review.
Topics: Amines; Amitriptyline; Analgesics; Anesthetics, Local; Antidepressive Agents, Tricyclic; Autonomic N | 2006 |
Complex regional pain syndrome-a multifaceted disorder requiring multidimensional care: case study.
Topics: Analgesics; Anesthetics, Local; Autonomic Nerve Block; Complex Regional Pain Syndromes; Guanethidine | 2008 |