guanethidine has been researched along with Chronic Primary Open Angle Glaucoma in 15 studies
Guanethidine: An antihypertensive agent that acts by inhibiting selectively transmission in post-ganglionic adrenergic nerves. It is believed to act mainly by preventing the release of norepinephrine at nerve endings and causes depletion of norepinephrine in peripheral sympathetic nerve terminals as well as in tissues.
guanethidine : A member of the class of guanidines in which one of the hydrogens of the amino group has been replaced by a 2-azocan-1-ylethyl group.
guanethidine sulfate : A organic sulfate salt composed of two molecules of guanethidine and one of sulfuric acid.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Thirty patients with ocular hypertension or open-angle glaucoma were tested to see if, and to what extent, guanethidine/dipivefrin and pilocarpine produced a supplementary reduction in intraocular pressure." | 7.67 | [Guanethidine/dipivefrin and pilocarpine in the treatment of increased intraocular pressure]. ( Dausch, D; Ober, M; Scharrer, A, 1987) |
| "The effect on the intraocular pressure of patients with primary open-angle glaucoma of a combination of timolol 0." | 5.06 | [Treatment of glaucoma chronicum simplex with a combination of 0.5 percent timolol with 0.5 percent adrenaline plus 0.3 percent guanethidine]. ( Grehn, F; Pfeiffer, N, 1989) |
| "Thirty patients with ocular hypertension or open-angle glaucoma were tested to see if, and to what extent, guanethidine/dipivefrin and pilocarpine produced a supplementary reduction in intraocular pressure." | 3.67 | [Guanethidine/dipivefrin and pilocarpine in the treatment of increased intraocular pressure]. ( Dausch, D; Ober, M; Scharrer, A, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| STEPANIK, J | 4 |
| O'Connor, MA | 1 |
| Mooney, DJ | 1 |
| Heilmann, K | 1 |
| Mills, KB | 2 |
| Hercules, B | 1 |
| English, M | 1 |
| Murray, A | 1 |
| Glover, D | 1 |
| Hitchings, R | 1 |
| Merkle, W | 1 |
| Pfeiffer, N | 2 |
| Grehn, F | 2 |
| Smith, RJ | 1 |
| Ober, M | 2 |
| Scharrer, A | 2 |
| Dausch, D | 1 |
| Vogel, R | 1 |
| Jacobs, N | 1 |
7 trials available for guanethidine and Chronic Primary Open Angle Glaucoma
| Article | Year |
|---|---|
The additional pressure-lowering effect in patients with glaucoma of pilocarpine 2 per cent, adrenaline 1 per cent, or guanethidine 3 per cent with adrenaline 0.5 per cent and timolol 0.25 per cent: a double-blind cross-over study.
Topics: Aged; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Epinephrine; Female; | 1983 |
Two blind randomized cross-over trials in the treatment of primary open angle glaucoma.
Topics: Aged; Clinical Trials as Topic; Drug Combinations; Drug Therapy, Combination; Epinephrine; Female; G | 1981 |
Low-dose combined guanethedine 1% and adrenaline 0.5% in the treatment of chronic simple glaucoma: a prospective study.
Topics: Aged; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Epinephrine; Female; | 1981 |
[Experience with combined therapy in the treatment of glaucoma: guanethidine/epinephrine compared with timolol/epinephrine (author's transl)].
Topics: Double-Blind Method; Drug Therapy, Combination; Epinephrine; Glaucoma, Open-Angle; Guanethidine; Hum | 1981 |
[Treatment of glaucoma chronicum simplex with a combination of 0.5 percent timolol with 0.5 percent adrenaline plus 0.3 percent guanethidine].
Topics: Clinical Trials as Topic; Drug Therapy, Combination; Epinephrine; Glaucoma, Open-Angle; Guanethidine | 1989 |
The Lang lecture 1986. The enigma of primary open-angle glaucoma.
Topics: Adult; Aged; Clinical Trials as Topic; Epinephrine; Female; Follow-Up Studies; Glaucoma, Open-Angle; | 1986 |
Timolol and guanethidine plus adrenaline in combination in the treatment of chronic open angle glaucoma.
Topics: Aged; Drug Therapy, Combination; Epinephrine; Female; Glaucoma, Open-Angle; Guanethidine; Humans; Ma | 1985 |
8 other studies available for guanethidine and Chronic Primary Open Angle Glaucoma
| Article | Year |
|---|---|
[The behavior of ocular pressure in eyes affected with simple glaucoma after the local use of guanethidine (Ismelin, Ciba)].
Topics: Amidines; Antihypertensive Agents; Eye; Glaucoma; Glaucoma, Open-Angle; Guanethidine; Head | 1961 |
[Tonographic and differential tonometric studies on the effect of Ismelin eye drops in glaucoma simplex].
Topics: Amidines; Antihypertensive Agents; Glaucoma; Glaucoma, Open-Angle; Guanethidine; Ophthalmic Solution | 1961 |
[2-octahydro-1'-azocinyl)-ethyl]-guanidine-sulfate (guanethidine) in glaucoma simplex].
Topics: Glaucoma; Glaucoma, Open-Angle; Guanethidine; Guanidine; Sulfates | 1962 |
[The intraocular pressure-decreasing effect of a 10/0 aqueous solution of guanethidine (Ismelin, Ciba) instilled into the conjunctival sac in glaucoma simplex].
Topics: Glaucoma; Glaucoma, Open-Angle; Guanethidine; Intraocular Pressure | 1963 |
[Behavior of intraocular pressure during long-term treatment with a guanethidine-adrenaline combination].
Topics: Adult; Aged; Drug Combinations; Epinephrine; Female; Glaucoma, Open-Angle; Guanethidine; Humans; Int | 1983 |
[Lowering the intraocular pressure by a combination of timolol with adrenergic agents].
Topics: Drug Therapy, Combination; Epinephrine; Glaucoma, Open-Angle; Guanethidine; Humans; Intraocular Pres | 1988 |
[Guanethidine/dipivefrin and pilocarpine in the treatment of increased intraocular pressure].
Topics: Drug Therapy, Combination; Epinephrine; Glaucoma, Open-Angle; Guanethidine; Humans; Intraocular Pres | 1987 |
[Experiences with the effectiveness and tolerance of guanethidine/dipivefrin-AT in the treatment of increased intraocular pressure].
Topics: Drug Therapy, Combination; Epinephrine; Glaucoma, Open-Angle; Guanethidine; Humans; Intraocular Pres | 1986 |