guanethidine has been researched along with Causalgia in 23 studies
Guanethidine: An antihypertensive agent that acts by inhibiting selectively transmission in post-ganglionic adrenergic nerves. It is believed to act mainly by preventing the release of norepinephrine at nerve endings and causes depletion of norepinephrine in peripheral sympathetic nerve terminals as well as in tissues.
guanethidine : A member of the class of guanidines in which one of the hydrogens of the amino group has been replaced by a 2-azocan-1-ylethyl group.
guanethidine sulfate : A organic sulfate salt composed of two molecules of guanethidine and one of sulfuric acid.
Causalgia: A complex regional pain syndrome characterized by burning pain and marked sensitivity to touch (HYPERESTHESIA) in the distribution of an injured peripheral nerve. Autonomic dysfunction in the form of sudomotor (i.e., sympathetic innervation to sweat glands), vasomotor, and trophic skin changes may also occur. (Adams et al., Principles of Neurology, 6th ed, p1359)
| Excerpt | Relevance | Reference |
|---|---|---|
| "This double-blind, randomized, multicenter study was designed to determine the short-term and long-term efficacy of intravenous regional block with guanethidine in patients with reflex sympathetic dystrophy (RSD)/causalgia." | 9.08 | Intravenous regional guanethidine in the treatment of reflex sympathetic dystrophy/causalgia: a randomized, double-blind study. Guanethidine Study Group. ( Hoffman, J; Ramamurthy, S, 1995) |
| "A 25-year-old female developed causalgia following a nerve injury in the left hand, and this was treated successfully with a series of intravenous guanethidine blocks." | 7.67 | A case of prolonged hypotension following intravenous guanethidine block. ( Carli, F; Milaszkiewicz, R; Sharpe, E, 1987) |
| "Two cases of the causalgia syndrome have been presented, one probably related to a mild peripheral neuropathy and the second, more classically, following trauma." | 5.26 | The causalgia syndrome treated with regional intravenous guanethidine. ( Holland, JT, 1978) |
| "This double-blind, randomized, multicenter study was designed to determine the short-term and long-term efficacy of intravenous regional block with guanethidine in patients with reflex sympathetic dystrophy (RSD)/causalgia." | 5.08 | Intravenous regional guanethidine in the treatment of reflex sympathetic dystrophy/causalgia: a randomized, double-blind study. Guanethidine Study Group. ( Hoffman, J; Ramamurthy, S, 1995) |
| "Guanethidine blockade was employed in 22 patients with causalgia, hyperpathia and reflex dystrophy in an upper limb." | 3.68 | [Guanethidine blockade for palliative treatment in reflex dystrophy]. ( Nielsen, FB; Olesen, AS, 1992) |
| "Intravenous regional sympathetic block with guanethidine caused only limited improvement in a patient with longstanding causalgia." | 3.67 | An unusual case of causalgia. Relevance to recent hypothesis on mechanism of causalgia. ( Charter, P; Hopkins, CS, 1989) |
| "A 25-year-old female developed causalgia following a nerve injury in the left hand, and this was treated successfully with a series of intravenous guanethidine blocks." | 3.67 | A case of prolonged hypotension following intravenous guanethidine block. ( Carli, F; Milaszkiewicz, R; Sharpe, E, 1987) |
| "Two cases of the causalgia syndrome have been presented, one probably related to a mild peripheral neuropathy and the second, more classically, following trauma." | 1.26 | The causalgia syndrome treated with regional intravenous guanethidine. ( Holland, JT, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 16 (69.57) | 18.7374 |
| 1990's | 7 (30.43) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hannington-Kiff, JG | 3 |
| Withrington, RH | 1 |
| Wynn Parry, CB | 2 |
| Parry, CB | 1 |
| Tabira, T | 1 |
| Shibasaki, H | 1 |
| Kuroiwa, Y | 1 |
| Nørregaard, TV | 1 |
| Schurizek, BA | 1 |
| Husegaard, HC | 1 |
| Ramamurthy, S | 1 |
| Hoffman, J | 1 |
| Breivik, H | 1 |
| Farcot, JM | 1 |
| Gautherie, M | 1 |
| Foucher, G | 1 |
| Schott, GD | 1 |
| Lamacraft, G | 1 |
| Price, CM | 1 |
| Prosser, AS | 1 |
| Rogers, PD | 1 |
| Pounder, D | 1 |
| Procacci, P | 1 |
| Zoppi, M | 1 |
| Maresca, M | 1 |
| Holland, JT | 1 |
| Onaka, M | 1 |
| Morimoto, M | 1 |
| Morimoto, E | 1 |
| Kurioka, M | 1 |
| Otada, H | 1 |
| Hyodo, M | 1 |
| Nielsen, FB | 1 |
| Olesen, AS | 1 |
| Hopkins, CS | 1 |
| Charter, P | 1 |
| McLelland, J | 1 |
| Ellis, SJ | 1 |
| Hodges, DL | 1 |
| McGuire, TJ | 1 |
| Davies, JA | 1 |
| Beswick, T | 1 |
| Dickson, G | 1 |
| Sharpe, E | 1 |
| Milaszkiewicz, R | 1 |
| Carli, F | 1 |
1 trial available for guanethidine and Causalgia
| Article | Year |
|---|---|
Intravenous regional guanethidine in the treatment of reflex sympathetic dystrophy/causalgia: a randomized, double-blind study. Guanethidine Study Group.
Topics: Adult; Causalgia; Double-Blind Method; Female; Guanethidine; Humans; Injections, Intravenous; Male; | 1995 |
22 other studies available for guanethidine and Causalgia
| Article | Year |
|---|---|
Pharmacological target blocks in hand surgery and rehabilitation.
Topics: Administration, Topical; Adolescent; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adul | 1984 |
The management of painful peripheral nerve disorders.
Topics: Causalgia; Denervation; Electric Stimulation; Guanethidine; Humans; Nerve Block; Neuralgia; Neurons, | 1984 |
The 1981 Philip Nichols Memorial Lecture.
Topics: Back Pain; Brachial Plexus; Causalgia; Electric Stimulation Therapy; Guanethidine; Humans; Nerve Com | 1982 |
Painful conditions of peripheral nerves.
Topics: Autonomic Nerve Block; Causalgia; Electric Stimulation; Female; Guanethidine; Humans; Median Nerve; | 1980 |
Reflex sympathetic dystrophy (causalgia) treatment with guanethidine.
Topics: Aged; Causalgia; Female; Guanethidine; Humans; Male; Middle Aged; Neuralgia; Spinal Diseases | 1983 |
Hyperadrenergic-effected limb causalgia: relief by IV pharmacologic norepinephrine blockade.
Topics: Autonomic Nerve Block; Causalgia; Extremities; Guanethidine; Humans; Neuralgia; Norepinephrine | 1982 |
[Intravenous block with guanethidine in the treatment of of hyperpathic painful conditions of the extremities].
Topics: Adult; Aged; Causalgia; Extremities; Female; Guanethidine; Humans; Injections, Intravenous; Male; Mi | 1982 |
Chronic pain and the sympathetic nervous system.
Topics: Autonomic Nervous System Diseases; Causalgia; Chronic Disease; Clinical Trials as Topic; Double-Blin | 1997 |
Regional intravenous sympathetic nerve blocks.
Topics: Adult; Aged; Anesthetics, Local; Autonomic Nerve Block; Causalgia; Female; Guanethidine; Humans; Mal | 1997 |
Interrupting the sympathetic outflow in causalgia and reflex sympathetic dystrophy.
Topics: Autonomic Nerve Block; Causalgia; Guanethidine; Humans; Meta-Analysis as Topic; Pain; Phentolamine; | 1998 |
Interrupting the sympathetic outflow in causalgia and reflex sympathetic dystrophy. Intravenous regional guanethidine blockage is a safe and effective treatment.
Topics: Autonomic Nerve Block; Causalgia; Guanethidine; Humans; Reflex Sympathetic Dystrophy; Sympatholytics | 1998 |
[Guanethidine therapy of reflex sympathetic syndromes].
Topics: Adult; Aged; Arterial Occlusive Diseases; Causalgia; Drug Evaluation; Edema; Female; Fibromyalgia; G | 1975 |
The retracted ephapse.
Topics: Arm; Autonomic Nerve Block; Causalgia; Guanethidine; Humans; Leg; Nerve Fibers; Neuralgia; Neurons, | 1978 |
Relief of causalgia in limbs yb regional intravenous guanethidine.
Topics: Adult; Aged; Anesthesia, Conduction; Anesthesia, Intravenous; Causalgia; Extremities; Guanethidine; | 1979 |
The causalgia syndrome treated with regional intravenous guanethidine.
Topics: Adolescent; Causalgia; Female; Guanethidine; Humans; Injections, Intravenous; Middle Aged; Neuralgia | 1978 |
[The clinical effect of intravenous regional sympathectomy with guanethidine in the management of sympathetically maintained pain].
Topics: Adult; Aged; Causalgia; Female; Guanethidine; Humans; Injections, Intravenous; Male; Middle Aged; Re | 1992 |
[Guanethidine blockade for palliative treatment in reflex dystrophy].
Topics: Adult; Aged; Arm; Autonomic Nerve Block; Causalgia; Female; Guanethidine; Humans; Infusions, Intrave | 1992 |
An unusual case of causalgia. Relevance to recent hypothesis on mechanism of causalgia.
Topics: Autonomic Nerve Block; Causalgia; Guanethidine; Humans; Male; Middle Aged; Neuralgia | 1989 |
Causalgia as a complication of meningococcal meningitis.
Topics: Adult; Causalgia; Guanethidine; Humans; Male; Meningitis, Meningococcal; Neuralgia | 1986 |
Burning and pain after injury. Is it causalgia or reflex sympathetic dystrophy?
Topics: Adrenal Cortex Hormones; Autonomic Nerve Block; Causalgia; Diagnosis, Differential; Exercise Therapy | 1988 |
Ketanserin and guanethidine in the treatment of causalgia.
Topics: Administration, Oral; Causalgia; Female; Guanethidine; Humans; Injections, Intravenous; Ketanserin; | 1987 |
A case of prolonged hypotension following intravenous guanethidine block.
Topics: Adult; Anesthesia, Intravenous; Autonomic Nerve Block; Causalgia; Female; Guanethidine; Hand; Humans | 1987 |