guanethidine has been researched along with Cardiovascular Stroke in 14 studies
Guanethidine: An antihypertensive agent that acts by inhibiting selectively transmission in post-ganglionic adrenergic nerves. It is believed to act mainly by preventing the release of norepinephrine at nerve endings and causes depletion of norepinephrine in peripheral sympathetic nerve terminals as well as in tissues.
guanethidine : A member of the class of guanidines in which one of the hydrogens of the amino group has been replaced by a 2-azocan-1-ylethyl group.
guanethidine sulfate : A organic sulfate salt composed of two molecules of guanethidine and one of sulfuric acid.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We sought to evaluate the effects of various doses of guanethidine, a sympathoinhibitory drug, on ventricular function and survival in chronic heart failure (CHF) after myocardial infarction (MI) in rats." | 7.72 | Long-term treatment with low-dose, but not high-dose, guanethidine improves ventricular function and survival of rats with heart failure after myocardial infarction. ( Asanoi, H; Fujii, N; Igawa, A; Inoue, H; Kato, B; Nozawa, T, 2003) |
| "We sought to evaluate the effects of various doses of guanethidine, a sympathoinhibitory drug, on ventricular function and survival in chronic heart failure (CHF) after myocardial infarction (MI) in rats." | 3.72 | Long-term treatment with low-dose, but not high-dose, guanethidine improves ventricular function and survival of rats with heart failure after myocardial infarction. ( Asanoi, H; Fujii, N; Igawa, A; Inoue, H; Kato, B; Nozawa, T, 2003) |
| "Guanethidine treatment caused significant reductions in systolic arterial blood pressure and indices of left ventricular contractility and relaxation (p less than 0." | 1.28 | Effect of chemical sympathectomy on cardiac hypertrophy and hemodynamics following myocardial infarction in the rat. ( Fishbein, MC; Rubin, SA, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (85.71) | 18.7374 |
| 1990's | 1 (7.14) | 18.2507 |
| 2000's | 1 (7.14) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Igawa, A | 1 |
| Nozawa, T | 1 |
| Fujii, N | 1 |
| Kato, B | 1 |
| Asanoi, H | 1 |
| Inoue, H | 1 |
| Diethelm, AG | 1 |
| Hartley, MW | 1 |
| Aldrete, JS | 1 |
| Sterling, WA | 1 |
| Morgan, JM | 1 |
| Rubin, SA | 1 |
| Fishbein, MC | 1 |
| Méhes, G | 1 |
| Rajkovits, K | 1 |
| Papp, G | 1 |
| Freis, ED | 1 |
| Cernigliaro, C | 1 |
| Fedele, F | 1 |
| Malaspina, F | 1 |
| Minuco, G | 1 |
| Rossi, P | 1 |
| Peart, WS | 1 |
| Moser, M | 1 |
| Cranston, WI | 1 |
| Staszewska-Barczak, J | 1 |
| Chung, EK | 1 |
| Morgan, EJ | 1 |
| Leon, AS | 1 |
| Abrams, WB | 1 |
| Kiesewetter, E | 1 |
| Ceremuzyński, L | 1 |
2 reviews available for guanethidine and Cardiovascular Stroke
| Article | Year |
|---|---|
Effectiveness of drug therapy in hypertension: present status. A review.
Topics: Antihypertensive Agents; Cerebrovascular Disorders; Coronary Disease; Eye Diseases; Ganglionic Block | 1971 |
Advances in medicine.
Topics: Acute Kidney Injury; Asthma; Blindness; Catecholamines; Contraceptives, Oral; Coronary Disease; Guan | 1968 |
2 trials available for guanethidine and Cardiovascular Stroke
| Article | Year |
|---|---|
The organization of a multi-centre randomized control therapeutic trial for mild to moderate hypertension.
Topics: Adult; Blood Pressure Determination; Clinical Trials as Topic; Female; Guanethidine; Humans; Hyperte | 1973 |
Treatment of hypertension--a pragmatic approach.
Topics: Antihypertensive Agents; Cerebrovascular Disorders; Clinical Trials as Topic; Erectile Dysfunction; | 1974 |
10 other studies available for guanethidine and Cardiovascular Stroke
| Article | Year |
|---|---|
Long-term treatment with low-dose, but not high-dose, guanethidine improves ventricular function and survival of rats with heart failure after myocardial infarction.
Topics: Animals; Catecholamines; Dose-Response Relationship, Drug; Guanethidine; Heart Failure; Male; Myocar | 2003 |
Treatment of accelerated hypertension and end stage renal failure by bilateral nephrectomy and renal transplantation.
Topics: Acute Kidney Injury; Adult; Biopsy; Blood Pressure; Child; Creatinine; Female; Graft Rejection; Guan | 1975 |
Effect of chemical sympathectomy on cardiac hypertrophy and hemodynamics following myocardial infarction in the rat.
Topics: Analysis of Variance; Animals; Blood Pressure; Cardiomegaly; Disease Models, Animal; Female; Guaneth | 1990 |
Effect of various types of sympathicolytics on isoproterenol-induced myocardial lesions.
Topics: Animals; Dibenzylchlorethamine; Ethanolamines; Guanethidine; Heart; Isoproterenol; Myocardial Infarc | 1966 |
[Medical treatment of dissecting acute aortic aneurysm complicated with myocardial infarct].
Topics: Acute Disease; Aged; Aortic Aneurysm; Female; Guanethidine; Humans; Male; Middle Aged; Myocardial In | 1974 |
The reflex stimulation of catecholamine secretion during the acute stage of myocardial infarction in the dog.
Topics: Acetylcholine; Adrenal Medulla; Animals; Bradykinin; Bretylium Compounds; Chlorisondamine; Dogs; Epi | 1971 |
Unusually marked sinus arrhythmia as a complication of acute diaphragmatic myocardial infarction.
Topics: Acute Disease; Arrhythmia, Sinus; Diaphragm; Digitalis Glycosides; Electrocardiography; Guanethidine | 1969 |
The role of catecholamines in producing arrhythmias.
Topics: Anesthetics; Antidepressive Agents; Arrhythmias, Cardiac; Atropine; Catecholamines; Digitalis Glycos | 1971 |
[Physiopathological deliberations on the significance of long-term therapy for hypertension].
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Cerebrovascular Disorders; Chlorothiazide; Fem | 1967 |
[Guanethidine (Ismelin) in bathmotropic disorders of heart rhythm].
Topics: Adult; Aged; Arrhythmias, Cardiac; Female; Guanethidine; Humans; Male; Middle Aged; Myocardial Infar | 1968 |