Page last updated: 2024-10-28

guanethidine and Basedow Disease

guanethidine has been researched along with Basedow Disease in 19 studies

Guanethidine: An antihypertensive agent that acts by inhibiting selectively transmission in post-ganglionic adrenergic nerves. It is believed to act mainly by preventing the release of norepinephrine at nerve endings and causes depletion of norepinephrine in peripheral sympathetic nerve terminals as well as in tissues.
guanethidine : A member of the class of guanidines in which one of the hydrogens of the amino group has been replaced by a 2-azocan-1-ylethyl group.
guanethidine sulfate : A organic sulfate salt composed of two molecules of guanethidine and one of sulfuric acid.

Research Excerpts

ExcerptRelevanceReference
"Assessment was made of 5% local guanethidine in treating eye manifestations in euthyroid patients with either treated thyrotoxicosis or ophthalmic Graves's disease."5.03Critical study of 5 per cent guanethidine in ocular manifestations of Graves's disease. ( Anderson, J; Cartlidge, NE; Crombie, AL; Hall, R, 1969)

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-199018 (94.74)18.7374
1990's0 (0.00)18.2507
2000's1 (5.26)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
LEAK, D1
DEGROOT, LJ1
Neves, LC1
Cruz, AA1
Hodes, BL1
Frazee, L1
Szmyd, S1
Bricaire, H1
Joly, J1
Laroche, C1
Grégoire, J1
Turpin, G1
Warnet, A1
Guerre, J1
Portos, JL1
Christoforov, B1
Péquignot, H1
Ivy, HK1
Haddad, HM1
Bowden, AN1
Rose, FC1
Cartlidge, NE1
Crombie, AL1
Anderson, J1
Hall, R1
Chwirot, R1
Gliński, J1
Berkman, N1
Joseph, E1
Storch, J1
Kjer, P1
Cant, JS2
Lewis, DR2
Harrison, MT1
Gay, AJ1
Wolkstein, MA1

Trials

2 trials available for guanethidine and Basedow Disease

ArticleYear
Dysthyroid eye disease. A trial of guanethidine eye drops.
    The British journal of ophthalmology, 1969, Volume: 53, Issue:4

    Topics: Clinical Trials as Topic; Eye Manifestations; Eyelids; Female; Graves Disease; Guanethidine; Humans;

1969
Critical study of 5 per cent guanethidine in ocular manifestations of Graves's disease.
    British medical journal, 1969, Dec-13, Volume: 4, Issue:5684

    Topics: Clinical Trials as Topic; Eye Manifestations; Eyelid Diseases; Female; Graves Disease; Guanethidine;

1969

Other Studies

17 other studies available for guanethidine and Basedow Disease

ArticleYear
Adrenergic blockade and thyrotoxicosis.
    Acta endocrinologica, 1963, Volume: 43

    Topics: Adrenergic Agents; Exophthalmos; Goiter; Graves Disease; Guanethidine; Humans; Thiouracil; Thyrotoxi

1963
THERAPY OF THYROTOXICOSIS.
    Modern treatment, 1964, Volume: 1

    Topics: Adolescent; Antithyroid Agents; Child; Female; Goiter; Graves Disease; Guanethidine; Heart Diseases;

1964
Effect of darkness on upper eyelid position.
    Ophthalmic plastic and reconstructive surgery, 2005, Volume: 21, Issue:2

    Topics: Adolescent; Adult; Age Distribution; Aged; Child; Child, Preschool; Darkness; Eyelids; Female; Grave

2005
Thyroid orbitopathy: an update.
    Ophthalmic surgery, 1979, Volume: 10, Issue:11

    Topics: Adult; Aged; Diplopia; Eyelids; Female; Graves Disease; Guanethidine; Humans; Oculomotor Muscles; Or

1979
Editorial: The eye signs of Graves disease.
    Lancet (London, England), 1974, Mar-23, Volume: 1, Issue:7856

    Topics: Edema; Exophthalmos; Eye; Eye Manifestations; Female; Graves Disease; Guanethidine; Humans; Male; Mu

1974
[Some recent progress in the medical treatment of hyperthyroidism].
    La Presse medicale, 1967, Jun-17, Volume: 75, Issue:29

    Topics: Adult; Antithyroid Agents; Female; Graves Disease; Guanethidine; Humans; Hydroxypropiophenone; Hyper

1967
[Therapy of acute thyrotoxic attacks].
    La Presse medicale, 1968, Dec-07, Volume: 76, Issue:48

    Topics: Adrenal Glands; Antithyroid Agents; Catecholamines; Cortisone; Drug Synergism; Graves Disease; Guane

1968
[Hyperthyroidism in general medicine].
    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1971, Oct-20, Volume: 47, Issue:40

    Topics: Adult; Aged; Carbimazole; Diarrhea; Electrocardiography; Emaciation; Female; Fever; France; Graves D

1971
Medical approach to ophthalmopathy of Graves' disease.
    Mayo Clinic proceedings, 1972, Volume: 47, Issue:12

    Topics: Adrenal Cortex Hormones; Adrenergic beta-Antagonists; Adrenocorticotropic Hormone; Diagnosis, Differ

1972
Pathogenesis and treatment of endocrine exophthalmos.
    International surgery, 1973, Volume: 58, Issue:7

    Topics: Blepharoptosis; Dexamethasone; Diplopia; Edema; Exophthalmos; Eye Neoplasms; Glaucoma; Graves Diseas

1973
[Effectiveness of guanethidine in preventing the retraction of the upper lid in Graves' disease].
    Klinika oczna, 1972, Volume: 42, Issue:3

    Topics: Adult; Eyelid Diseases; Female; Graves Disease; Guanethidine; Humans

1972
[Ocular manifestations of Basedow's disease and local administration of guanethidine].
    La Presse medicale, 1971, Jan-16, Volume: 79, Issue:3

    Topics: Eye Manifestations; Female; Graves Disease; Guanethidine; Humans; Male; Ophthalmic Solutions

1971
[Action of 5 per cent guanethidine sulfate (ismeline) eye drops on lid retraction during Basedow's disease].
    Annales d'oculistique, 1971, Volume: 204, Issue:6

    Topics: Adult; Eye Manifestations; Eyelid Diseases; Eyelids; Female; Graves Disease; Guanethidine; Humans; M

1971
[Retraction of the eyelids of endocrine origin treated with guanethidine (Ismelin) eyedrops].
    Ugeskrift for laeger, 1968, Jan-04, Volume: 130, Issue:1

    Topics: Adult; Eyelids; Female; Graves Disease; Guanethidine; Humans; Middle Aged; Ophthalmic Solutions

1968
Treatment of dysthyroid ophthalmopathy with local guanethidine.
    The British journal of ophthalmology, 1969, Volume: 53, Issue:4

    Topics: Eye Manifestations; Eyelids; Female; Graves Disease; Guanethidine; Humans; Hyperthyroidism; Male; Mi

1969
Unwanted pharmacological effects of local guanethidine in the treatment of dysthyroid upper lid retraction.
    The British journal of ophthalmology, 1969, Volume: 53, Issue:4

    Topics: Drug Hypersensitivity; Eye Manifestations; Eyelids; Female; Graves Disease; Guanethidine; Humans; Ke

1969
Topical guanethidine therapy for endocrine lid retraction.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1966, Volume: 76, Issue:3

    Topics: Eye Diseases; Eyelids; Graves Disease; Guanethidine; Humans

1966